Optimization and anticancer activity in vitro and in vivo of baohuoside I incorporated into mixed micelles based on lecithin and Solutol HS 15

References

• Abidin L, Mujeeb M, Imam SS, et al. (2015). Enhanced transdermal delivery of luteolin via non-ionic surfactant-based vesicle: quality evaluation and anti-arthritic assessment. Drug Deliv. [Epub ahead of print]. DOI: 10.3109/10717544.2014.945130
   PubMed Web of Science ®Google Scholar
• Ballinger AB1, Forget D, Le Brun A, et al. (1996). An evaluation of the safety of mixed micelles in healthy subjects. J Parenter Enteral Nutr 20:110–2
   PubMed Web of Science ®Google Scholar
• Buckingham LE, Balasubramanian M, Emanuele RM, et al. (1995). Comparison of solutol HS 15, cremophor EL and novel ethoxylated fatty acid surfactants as multidrug resistance modification agents. Int J Cancer 62:436–42
   PubMed Web of Science ®Google Scholar
• Buckingham LE, Balasubramanian M, Safa AR, et al. (1996). Reversal of multi-drug resistance in vitro by fatty acid PEG fatty acid diesters. Int J Cancer 65:74–9
   PubMed Web of Science ®Google Scholar
• Chen LC, Sha X, Jiang X, et al. (2013). Pluronic P105/F127 mixed micelles for the delivery of docetaxel against Taxol-resistant non-small cell lung cancer: optimization and in vitro, in vivo evaluation. Int J Nanomed 8:73–84
   PubMed Web of Science ®Google Scholar
• Chen Y, Jia X, Tan X, et al. (2009). Absorption and metabolism of flavonoids in Herba epimedii via rat intestinal perfusion model. Zhongguo Zhong Yao Za Zhi 34:2928–31
   PubMedGoogle Scholar
• Chen Y, Zhao YH, Jia XB, et al. (2008). Intestinal absorption mechanisms of prenylated flavonoids present in the heat-processed Epimedium koreanum Nakai (Yin Yanghuo). Pharm Res 25:2190–9
   PubMed Web of Science ®Google Scholar
• Cheng CY, Oh H, Wang TY, et al. (2014). Mixtures of lecithin and bile salt can form highly viscous wormlike micellar solutions in water. Langmuir 30:10221–30
   PubMed Web of Science ®Google Scholar
• Choi HJ, Eun JS, Kim DK, et al. (2008). Icariside II from Epimedium koreanum inhibits hypoxia-inducible factor-1alpha in human osteosarcoma cells. Eur J Pharmacol 579:58–65
   PubMed Web of Science ®Google Scholar
• Coon JS, Knudson W, Clodfelter K, et al. (1991). Solutol HS 15, nontoxic polyoxyethylene esters of 12-hydro-xystearic acid, reverses multidrug resistance. Cancer Res 51:897–902
   PubMed Web of Science ®Google Scholar
• Duan Y, Wang J, Yang X, et al. (2015). Curcumin-loaded mixed micelles: preparation, optimization, physicochemical properties and cytotoxicity in vitro. Drug Deliv 22:50–7
   PubMed Web of Science ®Google Scholar
• Fang J, Nakamura H, Maeda H. (2011). The EPR effect: unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect. Adv Drug Deliv Rev 63:136–51
   PubMed Web of Science ®Google Scholar
• Hu KL, Li JW, Shen YH, et al. (2009). Lactoferrin-conjugated PEG-PLA nanoparticles with improved brain delivery: in vitro and in vivo evaluations. J Control Release 134:55–61
   PubMed Web of Science ®Google Scholar
• Jeong EJ, Liu X, Jia X, et al. (2005). Coupling of conjugating enzymes and efflux transporters: impact on bioavailability and drug interactions. Curr Drug Metab 6:455–68
   PubMed Web of Science ®Google Scholar
• Ji X, Gao Y, Chen L, et al. (2012). Nanohybrid systems of non-ionic surfactant inserting liposomes loading paclitaxel for reversal of multidrug resistance. Int J Pharm 422:390–7
   PubMed Web of Science ®Google Scholar
• Jin X, Zhang ZH, Sun E, et al. (2012a). Preparation of a nanoscale baohuoside I-phospholipid complex and determination of its absorption: in vivo and in vitro evaluations. Int J Nanomed 7:4907–16
   PubMed Web of Science ®Google Scholar
• Jin X, Zhang ZH, Sun E, et al. (2012b). A novel drug–phospholipid complex loaded micelle for baohuoside I enhanced oral absorption: in vivo and in vitro evaluations. Drug Dev Ind Pharm 39:1421–30
   PubMed Web of Science ®Google Scholar
• Kim BS, Won M, Lee KM, et al. (2008). In vitro permeation studies of nanoemulsions containing ketoprofen as a model drug. Drug Deliv 15:465–9
   PubMed Web of Science ®Google Scholar
• Kim SH, Ahn KS, Jeong SJ, et al. (2011). Janus activated kinase 2/signal transducer and activator of transcription 3 pathway mediates icariside II-induced apoptosis in U266 multiple myeloma cells. Eur J Pharmacol 1:10–16
   Web of Science ®Google Scholar
• Kumar BS, Saraswathi R, Kumar KV, et al. (2014). Development and characterization of lecithin stabilized glibenclamide nanocrystals for enhanced solubility and drug delivery. Drug Deliv 21:173–84
   PubMed Web of Science ®Google Scholar
• Liu YQ, Yang QX, Cheng MC, et al. (2014). Synergistic inhibitory effect of Icariside II with Icaritin from Herba epimedii on pre-osteoclastic RAW264.7 cell growth. Phytomedicine 21:1633–7
   PubMed Web of Science ®Google Scholar
• Magee GA, French J, Gibbon B. (2003). Bile salt/lecithin mixed micelles optimized for the solubilization of a poorly soluble steroid molecule using statistical experimental design. Drug Dev Ind Pharm 29:441–50
   PubMed Web of Science ®Google Scholar
• Makhlof A, Tozuka Y, Takeuchi H. (2009). PH-sensitive nanospheres for colon-specific drug delivery in experimentally induced colitis rat model. Eur J Pharm Biopharm 72:1–8
   PubMed Web of Science ®Google Scholar
• Martinez-Perez C, Ward C, Cook G, et al. (2014). Novel flavonoids as anti-cancer agents: mechanisms of action and promise for their potential application in breast cancer. Biochem Soc Trans 42:1017–23
   PubMed Web of Science ®Google Scholar
• Mouri A, Diat O, Lerner DA, et al. (2014). Water solubilization capacity of pharmaceutical microemulsions based on Peceol®, lecithin and ethanol. Int J Pharm 475:324–34
   PubMed Web of Science ®Google Scholar
• Orlikova B, Menezes JC, Ji S, et al. (2014). Methylenedioxy flavonoids: assessment of cytotoxic and anti-cancer potential in human leukemia cells. Eur J Med Chem 84:173–80
   PubMed Web of Science ®Google Scholar
• Özcan I, Azizoğlu E, Senyiğit T, et al. (2013). Comparison of PLGA and lecithin/chitosan nanoparticles for dermal targeting of betamethasone valerate. J Drug Target 21:542–50
   PubMed Web of Science ®Google Scholar
• Panyama J, Sahoo SK, Prabha S, et al. (2003). Fluorescence and electron microscopy probes for cellular and tissue uptake of poly(d,l-lactide-co-glycolide) nanoparticles. Int J Pharm 262:1–11
   PubMed Web of Science ®Google Scholar
• Potluri P, Betageri GV. (2006). Mixed-micellar proliposomal systems for enhanced oral delivery of progesterone. Drug Deliv 13:227–32
   PubMed Web of Science ®Google Scholar
• Qian Q, Li SL, Sun E, et al. (2012). Metabolite profiles of icariin in rat plasma by ultra-fast liquid chromatography coupled to triple-quadrupole/time-of-flight mass spectrometry. J Pharm Biomed Anal 66:392–8
   PubMed Web of Science ®Google Scholar
• Rajebahadur M, Zia H, Nues A, et al. (2006). Mechanistic study of solubility enhancement of nifedipine using vitamin E TPGS or solutol HS-15. Drug Deliv 13:201–6
   PubMed Web of Science ®Google Scholar
• Ravishankar D, Rajora AK, Greco F, et al. (2013). Flavonoids as prospective compounds for anti-cancer therapy. Int J Biochem Cell Biol 45:2821–31
   PubMed Web of Science ®Google Scholar
• Singh MS, Lamprecht A. (2015). P-glycoprotein inhibition of drug resistant cell lines by nanoparticles. Drug Dev Ind Pharm. [Epub ahead of print]. DOI: 10.3109/03639045.2015.1054396
   Web of Science ®Google Scholar
• Song J, Shu L, Zhang Z, et al. (2012). Reactive oxygen species-mediated mitochondrial pathway is involved in Baohuoside I-induced apoptosis in human non-small cell lung cancer. Chem Biol Interact 199:9–17
   PubMed Web of Science ®Google Scholar
• Tong SW, Xiang B, Dong DW, et al. (2012). Enhanced antitumor efficacy and decreased toxicity by self-associated docetaxel in phospholipid-based micelles. Int J Pharm 434:413–9
   PubMed Web of Science ®Google Scholar
• Wachter C, Vierl U, Cevc G. (2008). Adaptability and elasticity of the mixed lipid bilayer vesicles containing non-ionic surfactant designed for targeted drug delivery across the skin. J Drug Target 16:611–25
   PubMed Web of Science ®Google Scholar
• Wen Z, Yan Z, He R, et al. (2011). Brain targeting and toxicity study of odorranalectin-conjugated nanoparticles following intranasal administration. Drug Deliv 18:555–61
   PubMed Web of Science ®Google Scholar
• Xiao HH, Fung CY, Mok SK, et al. (2014). Flavonoids from Herba epimedii selectively activate estrogen receptor alpha (ERα) and stimulate ER-dependent osteoblastic functions in UMR-106 cells. J Steroid Biochem Mol Biol 143:141–51
   PubMed Web of Science ®Google Scholar
• Yu X, Tong Y, Han XQ, et al. (2013). Anti-angiogenic activity of Herba epimedii on zebrafish embryos in vivo and HUVECs in vitro. Phytother Res 27:1368–75
   PubMed Web of Science ®Google Scholar
• Zhai YK, Guo X, Pan YL, et al. (2013). A systematic review of the efficacy and pharmacological profile of Herba epimedii in osteoporosis therapy. Pharmazie 68:713–22
   PubMed Web of Science ®Google Scholar