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Research Article

Sustained tissue drug concentrations following inhalation of liposome-encapsulated fentanyl in rabbits

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Pages 251-254 | Received 20 Sep 1995, Accepted 10 Dec 1995, Published online: 27 Sep 2008

References

  • Bakker-Woudenberg I. A., Lokerse A. F., Ten-Kate M. T., Melissen P. M., van Vianen W., Van Etten E. W. Liposomes as carriers of antimicrobial agents or immunomodulatory agents in the treatment of infections. Eur. J. Clin. Microbiol. Infect. Dis. 1993; 12: S61–S67
  • Bangham A. D., Standish M. M., Watkins J. C. Diffusion of univalent ions across the lamellae of swollen phospholipids. J. Mol. Biol. 1965; 13: 238–252
  • Bernards C. M., Luger T. J., Malmberg A. B., Hill H. F., Yaksh A. L. Liposome encapsulation prolongs alfentan spinal analgesia and alters systemic redistribution in the rat. Anesthesiology 1992; 77: 529–535
  • Fielding R. M. The use of inhaled liposome formulations for drug delivery to the lungs and systemic circulation. Proc. West. Pharmacol. Soc. 1989; 32: 103–106
  • Foong W. C., Harsanyi B. B., Mezei M. Effect of liposomes on hamster mucosa. J. Biomed. Mater. Res. 1989; 23: 1213–1229
  • Hung O. R., Whynot S. C., Varvel J. R., Shafer S. C., Mezei M. Pharmacokinetics of inhaled liposome-encapsulated fentanyl. Anesthesiology 1995; 83: 277–284
  • Kulkarni S. B., Betageri G. V., Singh M. Factors affecting microencapsulation of drugs in liposomes. J. Microencapsul. 1995; 12: 229–246
  • Meisner D., Pringle J., Mezei M. Liposomal pulmonary drug delivery. I: In vivo disposition of atropine base in solution and liposomal form following endotracheal instillation to the rabbit lung. J. Microencapsul. 1989; 6: 379–387
  • Meyer J., Whitcomb L., Collins D. Efficient encapsulation of proteins within liposomes for slow release in vivo. Biochem. Biophys. Res. Commun. 1994; 199: 433–438
  • Mezei M. Controlled release drug formulation through use of liposomes. Controlled Release Dosage Forms, H. P. Tipnis. Bombay College of Pharmacy, Bombay 1988; 37–46
  • Mezei M., Nugent J. F. Method of encapsulating biologically active materials in multilamellar lipid vesicles (MLV). U.S. Patent 1984; 4: 485, 054
  • Ostro M. J., Cullis P. R. Use of liposomes as injectable-drug delivery systems. Am. J. Hosp. Pharm. 1989; 46: 1576–1586
  • Oyarzun M. J., Clements J. A., Bavitussio A. Ventilation enhances pulmonary alveolar clearance of radioactive dipalmitoylphosphatidylcholine in liposomes. Am. Rev. Respir. Dis. 1980; 121: 709–720
  • Parnham M. J., Wetzig H. Toxicity screening of liposomes. Chem. Phys. Lipids 1993; 64: 263–274
  • Puglisi G., Fresta M., La Rosa C., Ventura C. A., Panico A. M., Mazzone G. Liposomes as a potential drug carrier for citicoline (CDP-choline) and the effect of formulation conditions on encapsulation efficiency. Pharmazie 1992; 47: 211–215
  • Ranade V. V. Drug delivery systems. 1. Site-specific drug delivery using liposomes as carriers. J. Clin. Pharmacol. 1989; 29: 685–694
  • Senior J. H. Liposomes in vivo: Prospects for liposome-based pharmaceuticals in the 1990s. Biotechnol. Genet. Eng. Rev. 1990; 8: 279–317
  • Tanaguchi K., Yamamato Y., Itakura K., Miichi H., Hayashi S. ssessment of ocular irritability of liposome preparations. J. Pharmacobiodyn. 1988a; 11: 607–611

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