A novel configuration of bioartificial liver support system based on circulating microcarrier culture

References

• Rozga J, Demetrious A A. Artificial liver: Evolution and future perspective. ASAIO Journal 1995; 41: 831–7
   PubMedGoogle Scholar
• Dixit V. Development of a bioartificial liver using isolated hepatocytes. Artif Organs 1994; 18: 371–84
   PubMed Web of Science ®Google Scholar
• Kasai S, Sawa M, Mito M. Is he biological artificial liver clinically applicable? A historic review of biological artificial liver support system. Artif Organs 1994; 18: 348–54
   PubMed Web of Science ®Google Scholar
• Galletti D M. Bioartificial organs. Artif Organs 1992; 55–60
   PubMedGoogle Scholar
• Nyberg S L, Peshwa M V, Payne W D, Hu W S, Cerra F B. Evolution of the bioartificial liver: The need for radomized clinical trials. The American Journal of Surgery 1993; 16: 512–21
   Google Scholar
• Denizli A, Piskin E, Dixit V, Arthus M, Gitnick G. Collagen and fibronectin immobilization on PHEMA microcarriers for hepatocyte attachment. Int J Artif Organs 1995; 18: 90–5
   PubMed Web of Science ®Google Scholar
• Koebe H G, Wick M, Cramer U, Lange V, Schildberg F W. Collagen gel immobilization provides a suitable cell matrix for long term human cultures in hybrid reactors. Int J Artif Organs 1994; 17: 95–106
   PubMed Web of Science ®Google Scholar
• Koike M, Matsushita M, Taguchi K, Uchino J. Function of culturing monolayer hepatocytes by collagen gel coating and coculture with nonparenchymal cells. Artif Organs 1996; 20: 186–92
   PubMedGoogle Scholar
• Gerlach J C, Encke J, Hole O, Muller C, Ryan C J, Neuhaus P. Bioreactor for a larger sacle hepatocyte in vitro perfusion. Transplantation 1994; 58: 1–7
   PubMedGoogle Scholar
• Wick M, Koebe H G, Schildberg. Extracorporeal artificial liver: the influence of a second cell layer on the morphology and function of immobilized human hepatocytes. Int J Artif Organs 1996; 19: 415–21
   PubMedGoogle Scholar
• Wu F J, Peshwa M V, Cerra F B, Hu W S. Entrapment of hepatocyte spheroids in a hollow fiber bioreactor as a potential bioartificial liver. Tissue Engineering 1995; 1: 29–39
   PubMedGoogle Scholar
• Gerlach J, Encke J, Hole O, Muller C, Courtney J M, Neuhaus P. Hepatocyte culture between three dimensionally arranged biomatrix-coated independent artificial capillary system and sinosoidal endothelial cell co-culture compartments. Int J Artif Organs 1994; 17: 191–6
   PubMedGoogle Scholar
• Gerlach J, Schnoy N, Smith M D, Neuhaus P. Hepatocyte culture between woven capillary networks: a microscopic study. Artif Organs 1994; 18: 226–30
   PubMedGoogle Scholar
• Vittinghus E. Preanalytical handling of stored urine samples, and measurement of (β2-microglobulin, orosomucoid, albumin, transferrin and immunoglobulin G in urine by enzyme-linked immunosorbent assay (ELISA). Scad J Clin Lab Invest 1990; 50: 843–9
   PubMed Web of Science ®Google Scholar
• Nyberg S L, Remmel R P, Mann H J, Peshwa M V, Hu W S, Cerra F B. Primary hepatocytes outperform Hep G2 cells as the source of biotransformation functions in a bioartificial liver. Annals of Surgery 1994; 220: 59–67
   PubMed Web of Science ®Google Scholar
• Sussman N L, Chong M G, Koussayer T, He D E, Shang T A, Whisennand H H, Kelly J H. Reversal of fulminant hepatic failure using an extracorporeal liver assist device. Hepatology 1992; 16: 60–5
   PubMed Web of Science ®Google Scholar
• Gislason G T, Lobdell D D, Kelly J H, Sussmann N L. A treatment system for implementing an extracorporeal liver assist device. Artif Organs 1994; 18: 385–9
   PubMed Web of Science ®Google Scholar
• Galletti P M, Jauregui H O. Liver support system. The Biomedical Engineering Handbok, J D Bronzino. CRC Press. 1952; 66
   Google Scholar
• Kasai S, Mito M. Cooperative works between medicine and engineering. Problems experienced in the national project for a new type of hybrid artificial liver support system and suggestions for the future. Jpn J Artif Organs 1992; 21: 16–9
   Google Scholar
• Rozga J, Williams F, Ro M S, Neuzil D F, Diorgio T D, Backfish G, Moscioni A D, Hakim R, Demetrious A A. Development of a bioartificial liver: Properties and functions of a hollow-fiber module inoculated with liver cells. Hepatology 1993; 17: 258–65
   PubMed Web of Science ®Google Scholar
• Nyberg S L, Shatford R A, Peshwa M V, White J G, Cerra F B, Hu W S. Evaluation of a hepatocyte-entrapment hollow fiber bioreactor: A potential bioartificial liver. Biotechnology and Bioengineering 1993; 4: 194–203
   Google Scholar
• Uchino J, Tsuburaya T, Kumagai F, et al. A hybrid bioartificial liver composed of multiplated hepatocyte monolsyers. ASAIO Transactions 1988; 34: 972–7
   PubMedGoogle Scholar
• Stang J, Mitzer S, Strau M, Fisher U, Lindemann S, Peters E, Holtz M, Drewelow B, Schmidt R. Primary or established liver cells for a hybrid liver? Comparison of metabolic features. ASAIO Journal 1995; 41: M310–5
   Google Scholar
• Shnyra A, Bocharov A, Bochkova N, Spirov V. Bioartificial liver using hepatocytes on Biosilon microcarriers: Treatment of chemically induced acute hepatic failure in rats. Artif Organs 1991; 15: 187–97
   Google Scholar
• Cunningham J M, Hodgson H JF. Microcarrier culture of hepatocytes in whole plasma for use in liver support bioreactors. Int J Artif Organs 1992; 15: 162–7
   PubMedGoogle Scholar
• Olumide F, Eliashiv A, Kralios N, Norton L, Eiseman B. Hepatic support with hepatocyte suspension in a permeable membrane dialyzer. Surgery 1977; 82: 599–606
   PubMedGoogle Scholar
• Bader A, Knop E, Fruhanf N, Crome O, Boker K, Christians U, Oldhafer K, Ringe B. Reconstruction of liver tissue in vitro. Geometry of characteristic flat bed, hollow fiber and spouted bed bioreactors with reference to the in vivo liver 1995; 19: 941–50
   Google Scholar
• Weber C, Rajnich C, Loth F, Schima H, Falkenhagen D. The microspheres based detoxification system (MDS): A new extracorporeal blood purification technology based recirculated microspherical adsorbent particles. Int J Artif Organs 1994; 17: 595–602
   PubMedGoogle Scholar
• Appen K, Weber C, Losert U, Schima H, Gurland H J, Falkenhagen D. Microspheres based detoxification system: A new method in convective blood purification. Artif Organs 1996; 20: 420–5
   PubMedGoogle Scholar
• Matsumura K N, Guevara G R, Huston H, et al. Hybrid bioartificial liver in hepatic failure: preliminary clinical report. Surgery 1987; 101: 99–103
   PubMed Web of Science ®Google Scholar
• Falkenhagen D. Patent: Arrangement for removing substances from liquids, in particular blood (International Patent Publications No. WO 95/04559). International Patent Classification. A61M 1/34, 1994
   Google Scholar