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Original Article

Hemoglobin Solution-from Tetramer to Polymer

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Pages 57-69 | Published online: 11 Jul 2009

References

  • Kaplan H P, Robinson F R, Kapanci Y, Weibel ER. Pathogenesis and reversibility of the pulmonary lesions of oxygen in monkeys. Lab Invest 1969; 20: 94–100
  • DeVenuto F, Friedman H, Neville J R, Peck C. Appraisal of hemoglobin solution as a blood substitute. Surg Gynecol Obstet 1979; 149: 417–36
  • Mulder A G, Amberson W R, Steggerda F R, Flexner J. Oxygen consumption with hemoglobin-ringer. J Cell Comp Physiol 1934; 5: 383–97
  • Moss G S, De Woskin R, Rosen A L, Levine H, Palani CK. Transport of oxygen and carbon dioxide by hemoglobin-saline solution in the red cell-free primate. Surg Gynecol Obstet 1976; 142: 357–62
  • Riggs T E, Shafer A W, Guenter CA. Acute changes in oxyhemoglobin affinity. J Clin Invest 1973; 52: 2660
  • Sunder-Plassmann L, Dieterle R, Seifcrt J, Fesch F, McSsmer K. Stroma free haemoglobin solution as a blood replacement fluid: Actual state and problems. Eur J Intensive Care Med 1975; 1: 37–42
  • Benesch R E, Benesch R, Renthal R D, Maeda N. Affinity labeling of the polyphosphate binding site of hemoglobin. Biochemistry 1972; 11: 3576–82
  • Greenberg A G, Hayashi R, Siefert I, Reese H, Peskin GW. Intravascular persistence and oxygen delivery of pyridoxylated stroma-free hemoglobin during gradations of hypotension. Surgery 1979; 86: 13–6
  • Sehgal L R, Rosen A L, Noud G. Large volume preparation of pyridoxylated hemoglobin with high P50. J Surg Res 1981; 30: 14–20
  • Rabiner S F, Friedman LH. The role of intravascular hemolysis and the reticuloendothelial system in the production of a hypercoagulable state. Br J Haematol 1968; 14: 105–18
  • Gould S A, Sehgal L R, Rosen A L, Sehgal H L, Levine H D, Rice C L, Moss GS. Hemoglobin solution: Is a normal [Hb] or P50 more important. J Surg Res 1982; 33: 189–93
  • Sehgal L R, Rosen A L, Gould S A, Sehgal H L, Moss GS. An appraisal of polymerized pyridoxylated hemoglobin as an acellular oxygen carrier. Blood substitutes, Geyer Bolin. Alan R Liss Inc, New York 1983; 19–28
  • Sehgal L R, Rosen A L, Gould S A. Preparation and in vitro characteristics of polymerized pyridoxylated hemoglobin. Transfusion 1983; 23: 148–52
  • Sehgal L R, Rosen A, Gould S. In vitro and in vivo characteristics of polymerized pyridoxylated hemoglobin solution. Fed Proc 1980; 39: 2383
  • Hamilton P B, Hiller A, Van Slyke DD. Renal effects of hemoglobin infusions in dogs in hemorrhagic shock. J Exp Med 1948; 85: 477–87
  • Rabiner S F, Friedman LH. The role of intravascular hemolysis and the reticuloendothelial system in the production of a hypercoagulable state. Br J Haematol 1968; 14: 105–18
  • Rabiner S F, Helbert J R, Lopas H, Friedman LH. Evaluation of a stroma-free hemoglobin solution for use as a plasma expander. J Exp Med 1967; 126: 1127–42
  • Birndorf N I, Lopas H. Effects of red cell stroma-free hemoglobin solution on renal function in monkeys. J Appl Physiol 1970; 29: 573–8
  • Savitsky J P, Doczi J, Black J, Arnold JD. A clinical safety trial of stroma-free hemoglobin. Clin Pharmacol Ther 1978; 23: 73–80
  • Hau T, Simmons RL. Mechanisms of the adjuvant effect of hemoglobin in experimental peritonitis. III. The influence of hemoglobin on phagocytosis and intracellular killing by human granulocytes. Surgery 1980; 87: 588–92
  • Hoyt D B, Greenberg A G, Peskin G W, Forbes S, Reese H. Resuscitation with pyridoxylated stroma free hemoglobin: Tolerance to sepsis. J Trauma 1981; 21: 938–42
  • Litwin M D, Walter C W, Ejarque P, Reynolds ES. Synergistic toxicity of gram-negative bacteria and free colloidal hemoglobin. Ann Surg 1963; 157: 485–93
  • Stein P M, Saba TM. Cardiovascular response to hemorrhage in the dog as modified by colloid induced opsonic deficiency and reticuloendothelial blockade. Fed Proc 1979; 38: 1115

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