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Biomaterials, Artificial Cells and Artificial Organs Volume 18, 1990 - Issue 5
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Original Article

A Screening Test for Modified Hemoglobin Blood Substitutes Before Clinical Use: Based on C3a Complement Activation in Human Plasma

T. M. S. Chang Artificial Cells and Organs Research Centre Faculty of Medicine, McGill University, 3655 Drummond St., Montreal, PQ, Canada, H3G 1Y6
&
C. Lister Artificial Cells and Organs Research Centre Faculty of Medicine, McGill University, 3655 Drummond St., Montreal, PQ, Canada, H3G 1Y6
Pages 693-701 | Published online: 11 Jul 2009

References

  • Blood Substitutes, T. M.S. Chang, R. Geyer. Marcel Dekker Publisher, New York 1989; 716
  • Chang T. M.S., Geyer R. Special Issue “III International Symposium on Blood substitutes”. J. Biomaterials Artificial Cells & Artificial Organs. 1988; 16: 1–703
  • Winslow R. M., Chang T. M.S. Special Issue on “Red Blood Cell substitutes”. J. Biomaterials Artificial Cells & Artificial Organs. 1990; 18: 133–365
  • Ning J., Chang T. M.S. Effects of stroma-free hemoglobin and polyhemoglobin on blood cells, complement activation and coagulation factors in rats(abs). J. Biomaterials Artificial Cells & Artificial Organs 1987; 15: 380
  • Ning J., Chang T. M.S. Effects of stroma-free hemoglobin and polyhemoglobin on blood cells, complement activation and coagulation factors in rats. J. Biomaterials Artificial Cells & Artificial Organs 1988; 16: 651–652
  • Ning J., Chang T. M.S. Whole Complement hemolytic activity (CH50) following infusion of stroma-free and polyhemoglobin solutions in rats. J. Biomaterials Artificial Cells & Artificial Organs 1990a; 18: 203–218
  • Ning J., Chang T. M.S. Effects of homologous and heterologous stroma-free hemoglobin and polyhemoglobin on complement activation, leucocytes and platelets. J. Biomaterials Artificial Cells & Artificial Organs. 1990b; 18: 219–232
  • Chang T. M.S. Editorial: modified hemoglobin: endotoxin and safety studies. J. Biomaterials Artificial Cells & Artificial Organs. 1990; 18: vii–viii, 1990
  • Feola M., Simoni J., Tran R., Canizaro P. C. Mechanisms of toxicity of hemoglobin solutions. J. Biomaterials Artificial Cells & Artificial Organs. 1988a; 18: 217–226
  • Feola M., Simoni J., Canizaro P. C. Complement activation and the toxicity of stroma-free hemoglobin solution in primates. Cir Shock. 1988b; 25: 275–290
  • Hammerschmidt D. E., Vercellotti G. M. Limitation of complement activation by perfluorocarbon emulsions superiority of lecithin-emulsified preparations. J. Biomaterial, Artificial Cells & Artificial Organs 1988; 18: 431–438
  • Malgras J., Hauptmann G., Zorn J. J., Waitz R. Mesure de l'activite anti-complementaire des preparations de gamma-galobulines injectables par voie intra-veineuse. Revue Francaise de Transfusion. 1970; 13: 173–180

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