α-α Diaspirin Crosslinked Hemoglobin, Nitric Oxide, and Cerebral Ischemic Injury in Rats

References

• Harrison M JG. Influence of haematocrit in the cerebral circulation. Cerebrovas Brain Metab Rev 1989; 1: 55–67
   PubMedGoogle Scholar
• Cole D J, Schell R M, Pryzbelski R J, Drummond J C, Bradley K. Focal cerebral ischemia in rats: effect of hemodilution with α-α cross-linked hemoglobin on CBF. J Cereb Blood Flow Metab 1992; 12: 971–976
   PubMedGoogle Scholar
• Cole D J, Drummond J C, Patel P M, Marcantonio S. Effects of viscosity and oxygen content on cerebral blood flow in ischemic and normal rat brain. J Neurol Sci 1994; 124: 15–20
   PubMed Web of Science ®Google Scholar
• Muizelaar J P, Bouma G J, Levasseur J E, Kontos HA. Effect of hematocrit variations on cerebral blood flow and basilar artery diameter in vivo. Am J Physiol 1992; 262: H949–H954
   PubMedGoogle Scholar
• Lee S H, Heros R C, Mullan J C, Korosue K. Optimum degree of hemodilution for brain protection in a canine model of focal cerebral ischemia. J Neurosurg 1994; 80: 469–475
   PubMedGoogle Scholar
• Cole D C, Schell R M, Drummond J C, Reynolds L. Focal cerebral ischemia in rats: effect of hypervolemic hemodilution with diaspirin cross-linked hemoglobin versus albumin on brain injury and edema. Anesthesiology 1993; 78: 335–342
   PubMed Web of Science ®Google Scholar
• Alayash A I, Fratantoni J C, Bonaventura C, Bonaventura J, Cashon RE. Nitric oxide binding to human ferrihemoglobins cross-linked between either α or β subunits. Arch Biochem Biophys 1993; 303: 332–338
   PubMed Web of Science ®Google Scholar
• Martin W, Villani G M, Jothianandan D, Furchgott RF. Selective blockade of endothelium-dependent and glyceryl trinitrate-induced relaxation by hemoglobin and by methylene blue in rabbit aorta. J Pharmacol Exp Ther 1985; 232: 708–716
   PubMed Web of Science ®Google Scholar
• Beckman J. The double-edged role of nitric oxide in brain function and superoxide-mediated injury. J Dev Physiol 1991; 15: 53–59
   PubMedGoogle Scholar
• Dalkara T, Moskowitz MA. The complex role of nitric oxide in the pathogenesis of focal cerebral ischemia. Brain Pathol 1994; 4: 49–57
   PubMed Web of Science ®Google Scholar
• Dawson DA. Nitric oxide and focal cerebral ischemia: multiplicity of actions and diverse outcome. Cerebrovasc Brain Metab Rev 1994; 6: 299–324
   PubMedGoogle Scholar
• Ashwal S, Cole D J, Osborne T N, Pearce WJ. Dual effects of L-NAME during transient focal cerebral ischemia in the spontaneously hypertensive rat. Am J Physiol 1994; 267: H276–H284
   PubMedGoogle Scholar
• Ashwal S, Cole D J, Osborne T N, Pearce WJ. Low dose L-NAME reduces infarct volume in the rat MCAO/REPERFUSION model. J Neurosurg Anesthesiol 1993; 5: 241249
   Google Scholar
• Buisson A, Plotkine M, Boulu RG. The neuroprotective effect of a nitric oxide inhibitor in a rat model of focal cerebral ischaemia. Br J Pharmacol 1992; 106: 766–767
   PubMed Web of Science ®Google Scholar
• Nowicki J P, Duval D, Poignet H, Scatton B. Nitric oxide mediates neuronal death after focal cerebral ischemia in the mouse. Eur J Pharmacol 1991; 204: 339–340
   PubMed Web of Science ®Google Scholar
• Yamamoto S, Golanov E V, Berger S C, Reis DJ. Inhibition of nitric oxide synthesis increases focal ischemic infarction in rat. J Cereb Blood Flow Metab 1992; 12: 717–726
   PubMedGoogle Scholar
• Zhang F, Iadecola C. Nitroprusside improves blood flow and reduces brain damage after focal ischemia. Neuro Report 1993; 4: 559–562
   PubMed Web of Science ®Google Scholar
• Chatterjee R, Welty E V, Walder R Y, Pruitt S L, Rogers P H, Arnone A, Walder JA. Isolation and characterization of a new hemoglobin derivative cross-linked between α chains (lysine 99α 99α2). J Biol Chem 1986; 261: 9929–9937
   PubMed Web of Science ®Google Scholar
• Hess J R, Fadare S O, Tolentino L SL, Bangal NR. The intravascular persistence of DBBF-hemoglobin. Progress in Clinical and Biological Research (Red Cell: 7^th Ann Arbor Conference), B Brewer. Alan R. Liss, New York 1989; 351–360
   Google Scholar
• Estep T N, Bechtel M K, Miller T J, Bagdasarian A. Virus inactivation in hemoglobin solutions by heat. Blood Substitutes, TMS Chang, RP Geyer. Marcel Dekker, New York 1989; 129–134
   Google Scholar
• Estep T N, Bechtel M K, Bush S L, Miller T J, Szeto S, Webb LE. The purification of hemoglobin solutions by heating. Prog Clin Biol Res 1989; 319: 325–336
   PubMedGoogle Scholar
• Vandergriff K D, Medina F, Marini M A, Winslow RM. Equilibrium oxygen binding to αα-cross-linked human hemoglobin. J Biol Chem 1988; 17824–17833
   Google Scholar
• DeVenuto F, Busse K R, Zegna AI. Viscosity of human blood hemodiluted with crystalline hemoglobin solution. Transfusion 1981; 21: 752–756
   PubMedGoogle Scholar
• Ashwal S, Cole D J, Osborne S, Osborne T N, Pearce WJ. L-NAME reduces infarct volume in a filament model of transient middle cerebral artery occlusion in the rat pup. Pediatr Res 1995; 38: 652–656
   PubMed Web of Science ®Google Scholar
• Katsuyama S S, Cole D J, Drummond J C, Bradley K. Nitric oxide mediates the hypertensive response to a modified hemoglobin solution (DCLHbTM) in rats. Art Cells, Blood Subs, and Immob Biotech 1994; 22: 1–7
   PubMed Web of Science ®Google Scholar
• Park C, Mendelow A, Graham D, McCulloch J, Teasdale G. Correlation of triphenyltetrazolium chloride perfusion staining with conventional neurohistology in the detection of early brain ischaemia. Neuropathol Appl Neurobiol 1988; 14: 289–298
   PubMed Web of Science ®Google Scholar
• Wilkinson L. Multivariate General Linear Hypothesis. SYSTAT: The System for Statistics. SYSTAT, Inc., Evanston, IL 1987; 22–30
   Google Scholar
• Korosue K, Heros RC. Mechanism of cerebral blood flow augmentation by hemodilution in rabbits. Stroke 1992; 23: 1497–1493
   Google Scholar
• Watkins LD. Nitric oxide and cerebral blood flow: an update. Cerebrovasc Brain Metab Rev 1995; 7: 324–337
   PubMedGoogle Scholar
• Malinski T, Bailey F, Zhang Z G, Chopp M. Nitric oxide measured by a porphyrinic microsensor in rat brain after transient middle cerebral artery occlusion. J Cereb Blood Flow Metab 1993; 13: 355–358
   PubMed Web of Science ®Google Scholar
• Tominaga T, Sato S, Ohnishi T, Ohnishi ST. Electron paramagnetic resonance (EPR) detection of nitric oxide produced during forebrain ischemia of the rat. J Cereb Blood Flow Metab 1994; 14: 715–722
   PubMed Web of Science ®Google Scholar
• Uemura Y, Kowall N W, Beal MF. Selective sparing of NADPH-diaphorase-somatostatic-neuropeptide Y neurons in ischemic gerbil striatum. Ann Neurol 1990; 27: 620–625
   PubMedGoogle Scholar
• Choi DW. Nitric oxide: foe or friend to the injured brain. Proc Natl Acad Sci USA 1993; 90: 9741–9743
   PubMed Web of Science ®Google Scholar
• Beckman J S, Beckman T W, Chen J, Marshall P A, Freeman BA. Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc Natl Acad Sci USA 1990; 87: 1620–1624
   PubMed Web of Science ®Google Scholar
• Boje K M, Arora PK. Microglial-produced nitric oxide and reactive nitrogen oxides mediate neuronal cell death. Brain Res 1992; 587: 250–256
   PubMed Web of Science ®Google Scholar
• Zhang F, Xu S, Iadecola C. Time dependence of effect of nitric oxide synthase inhibition on cerebral ischemic damage. J Cereb Blood Flow Metab 1995; 15: 595–601
   PubMed Web of Science ®Google Scholar
• Huang Z, Huang P L, Panahian N, Dalkara T, Fishman M C, Moskowitz MA. Effects of cerebral ischemia in mice deficient in neuronal nitric oxide synthase. Science 1994; 265: 1883–1885
   PubMed Web of Science ®Google Scholar
• Rees D D, Palmer R MJ, Schulz R, Hodson H F, Moncada S. Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo. Br J Pharmacol 1990; 101: 746–752
   PubMed Web of Science ®Google Scholar
• Van Gelderen E M, Heiligers J PC, Saxena PR. Haemodynamic changes and acetylcholine-induced hypotensive responses after NG-nitro-L-arginine methyl ester in rats and cats. Br J Pharmacol 1991; 103: 1899–1904
   PubMedGoogle Scholar
• Gardiner S M, Compton A M, Kemp P A, Bennett T. Regional and cardiac haemodynamic effects of NG-nitro-L-arginine methyl ester in conscious Long Evans rats. Br J Pharmacol 1990; 101: 625–631
   PubMed Web of Science ®Google Scholar
• Lahera V, Salom M G, Miranda-Guardiola M, Moncada S, Romero JC. Effects of NG-nitro-L-arginine methyl ester on renal function and blood pressure. Am J Physiol 1991; 261: F1033–F1037
   PubMed Web of Science ®Google Scholar
• Cole D J, Drummond J C, Osborne T N, Matsurnura J. Hypertension and hemodilution during cerebral ischemia reduce brain injury and edema. Am J Physiol 1990; 259: H211–H217
   PubMedGoogle Scholar
• Buisson A, Margaill I, Callebert J, Plotkine M, Boulu RG. Mechanisms involved in the neuroprotective activity of a nitric oxide synthase inhibitor during focal cerebral ischemia. J Neurochem 1993; 61: 690–696
   PubMed Web of Science ®Google Scholar
• Carreau A, Duval D, Poignet H, Scatton B, Vigé X, Nowicki J-P. Neuroprotective efficacy of N-nitro-L-arginine after focal cerebral ischemia in the mouse and inhibition of cortical nitric oxide synthase. Eur J Pharmacol 1994; 256: 241–249
   PubMed Web of Science ®Google Scholar
• Hasegawa T, Takagi S, Nishimaki K, Morita K, Nakajima S. Impairmanet of L-arginine metabolism in spontaneously hypertensive rats. Biochem Int 1992; 26: 653–658
   PubMedGoogle Scholar
• Duverger D, MacKenzie ET. The quantification of cerebral infarction following focal ischemia in the rat: influence of strain, arterial pressure, blood glucose concentration, and age. J Cereb Blood Flow Metab 1988; 8: 449–461
   PubMed Web of Science ®Google Scholar
• Panza J A, Casino P R, Kilcoyne C M, Quyyumi AA. Role of endothelium-derived nitric oxide in the abnormal endothelium-dependent vascular relaxation of patients with essential hypertension. Circulation 1993; 87: 1468–1474
   PubMed Web of Science ®Google Scholar
• Panza J A, Casino P R, Badar D M, Quyyumi AA. Effect of increased availability of endothelium-derived nitric oxide precursor on endothelium-dependent vascular relaxation in normal subjects and in patients with essential hypertension. Circulation 1993; 87: 1475–1481
   PubMed Web of Science ®Google Scholar
• Archer S. Measurement of nitric oxide in biological models. FASEB 1993; J 7: 349–360
   PubMedGoogle Scholar