13
Views
1
CrossRef citations to date
0
Altmetric
Research Article

Solubilisation of A Novel Anticonvulsant Binding Site From Pig Cortical Membranes

, , &
Pages 167-186 | Published online: 26 Sep 2008

References

  • Upton N., Blackburn T. P., Cooper D., Herdon H. J., Stean T. O., Evans M. L., Ray A. M., Chan W. N., Evans J. M., Thompson M., Campbell C. A., King P. D. Profile of SB-204269, a mechanistically novel anticonvulsant drug, in rat models of focal and generalised epileptic seizures. Br. J. Pharmacol. 1997; 121: 1679–1686
  • Herdon H. J., Jerman J. C., Stean T. O., Middlemiss D. N., Chan W. N., Vong A. K., Evans J. M., Thompson M., Upton N. Characterisation of the binding of [3H]-SB-204269, a radiolabeled form of the new anticonvulsant SB-204269, to a novel binding site in rat brain membranes. Br. J. Pharmacol. 1997; 121: 1687–1691
  • Herdon H. J., Jerman J. C., Stean T. O., Chan W. N., Middlemiss D. N., Upton N. Identification of a stereoselective CNS binding site for the novel anticonvulsant SB-204269. Eur. J. Pharmacol. 1996; 314: R7–R8
  • Herdon H. J., Chan W. N., Upton N. Use of the new radioligand [125I]-SB-217644 for characterisation of the novel anticonvulsant SB-204269 binding site in brain tissue and cell lines. Eur. J. Neurosci. 1998; 10(suppl 10)20–52
  • De Beer J. O., Vandenbroucke C. V., Massart D. L., De Spiegeleer B. M. Half-fraction and full factorial designs versus central composite design for retention modelling in reversed-phase ion-pair liquid chromatography. J. Pharmac. Biomed. Anal. 1996; 14(5)525–541
  • Haaland P. D. Experimental Design in Biotechnology. Marcel Dekker, Inc., New York, N.Y. 1989
  • Hunter W. G., Hunter J. S. Statistics for Experimenters. John Wiley & Sons. 1978
  • Reiken S. R., Van Wie B. J., Sutisana H., Kurdikar D. L., Davis W. C. Efficient optimisation of ELISAs. J. Immunol. Methods 1994; 177: 199–206
  • Bradford M. M. A. rapid and sensitive method for the quantification of microgram quantities of protein utilising the principle of protein-dye binding. Anal. Biochem. 1976; 72: 248–254
  • Bowen W. P., Jerman J. Nonlinear regression using spreadsheets. Trends Pharmacol. Sci. 1995; 16: 413–417
  • Cheng Y. C., Prusoff W. H. Relationship between the inhibition constant (Ki) and the concentration of inhibitor which causes 50 percent inhibition (I50) of an enzymatic reaction. Biochem. Pharmacol. 1973; 22: 3099–3108
  • Fletche S., Barnes N. M. Purification of 5-HT3 receptors from porcine brain. Br. J. Pharmacol. 1997; 122: 655–662
  • McKeman R. M., Quirk K., Jackson R. G., Ragan C. I. Solubihsation of the 5-HT3 receptor from pooled rat cortical and hippocampal membranes. J. Neurochem. 1990; 54: 924–930
  • McKeman R. M., Castro S., Poat J. A., Wong E. H.F. Solubihsation of the N-methyl-D-aspartate receptor channel complex from rat and porcine brain. J. Neurochem. 1989; 52: 777–785
  • Goldberg M. E., Expertbezancon N., Vuillard L., Rabilloud T. Non-detergent sulphobetaines-a new class of molecules that facilitate in vitro protein renaturation. Folding & Design 1996; 1: 21–27
  • Vuillard L., Braunbreton C., Rabilloud T. Non-detergent sulphobetaines-a new class of mild solubilisation agents for protein purification. Biochem. J. 1995a; 305: 337–343
  • Vuillard L., Madern D., Franzetti B., Rabilloud T. Halophilic protein stabilisation by the mild solubilising agents nondetergent sulfobetaines. Anal. Biochem. 1995b; 230: 290–294
  • Chazot P. L., Stephenson F. A. Biochemical evidence for the existence of a pool of unassembled C2 exon-containing NR1 subunits of the mammalian forebrain NMDA receptor. J. Neurochem. 1997; 68: 507–516
  • Cornell J. A. Experiments with Mixtures. John Wiley & Sons. 1990
  • Myers R. H., Montgomery C. Response Surface Methodology. John Wiley & Sons. 1995
  • Bristow D. R., Martin I. L. Solubilisation of the benzodiazepine receptor from the rat cerebellum by the detergent n-octylpentaoxyethylene. J. Neurochem. 1987; 48: 1537–1540

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.