GABRB3 gene expression increases upon ethanol exposure in human embryonic stem cells

References

• Agashe D, Bolnick DI. Intraspecific genetic variation and competition interact to influence niche expansion. Proc Biol Sci 2010, 277, 2915–2924.
   Google Scholar
• Andäng M, Hjerling-Leffler J, Moliner A, Lundgren TK, Castelo-Branco G, Nanou E, Pozas E, Bryja V, Halliez S, Nishimaru H, Wilbertz J, Arenas E, Koltzenburg M, Charnay P, El Manira A, Ibañez CF, Ernfors P. Histone H2AX-dependent GABA(A) receptor regulation of stem cell proliferation. Nature 2008, 451, 460–464.
   PubMedGoogle Scholar
• Anthony B, Zhou FC, Ogawa T, Goodlett CR, Ruiz J. Alcohol exposure alters cell cycle and apoptotic events during early neurulation. Alcohol Alcohol 2008, 43, 261–273.
   PubMed Web of Science ®Google Scholar
• Chastain G. Alcohol, neurotransmitter systems, and behavior. J Gen Psychol 2006, 133, 329–335.
   PubMed Web of Science ®Google Scholar
• Coles CD, Kable JA, Drews-Botsch C, Falek A. Early identification of risk for effects of prenatal alcohol exposure. J Stud Alcohol 2000, 61, 607–616.
   PubMed Web of Science ®Google Scholar
• Dettmer TS, Barnes A, Iqbal U, Bailey CD, Reynolds JN, Brien JF, Valenzuela CF. Chronic prenatal ethanol exposure alters ionotropic glutamate receptor subunit protein levels in the adult guinea pig cerebral cortex. Alcohol Clin Exp Res 2003, 27, 677–681.
   Google Scholar
• Deutsch S, Lyle R, Dermitzakis ET, Attar H, Subrahmanyan L, Gehrig C, Parand L, Gagnebin M, Rougemont J, Jongeneel CV, Antonarakis SE. Gene expression variation and expression quantitative trait mapping of human chromosome 21 genes. Hum Mol Genet 2005, 14, 3741–3749.
   PubMed Web of Science ®Google Scholar
• Eravci M, Kley S, Pinna G, Prengel H, Brödel O, Hiedra L, Meinhold H, Baumgartner A. Gene expression of glucose transporters and glycolytic enzymes in the CNS of rats behaviorally dependent on ethanol. Brain Res Mol Brain Res 1999, 65, 103–111.
   Google Scholar
• Eravci M, Schulz O, Grospietsch T, Pinna G, Brödel O, Meinhold H, Baumgartner A. Gene expression of receptors and enzymes involved in GABAergic and glutamatergic neurotransmission in the CNS of rats behaviourally dependent on ethanol. Br J Pharmacol 2000, 131, 423–432.
   Google Scholar
• Fielden MR, Zacharewski TR. Challenges and limitations of gene expression profiling in mechanistic and predictive toxicology. Toxicol Sci 2001, 60, 6–10.
   PubMed Web of Science ®Google Scholar
• Gauthier TW, Kable JA, Burwell L, Coles CD, Brown LA. Maternal alcohol use during pregnancy causes systemic oxidation of the glutathione redox system. Alcohol Clin Exp Res 2010, 34, 123–130.
   PubMedGoogle Scholar
• Gouya L, Puy H, Robreau AM, Bourgeois M, Lamoril J, Da Silva V, Grandchamp B, Deybach JC. The penetrance of dominant erythropoietic protoporphyria is modulated by expression of wildtype FECH. Nat Genet 2002, 30, 27–28.
   PubMed Web of Science ®Google Scholar
• Hamadeh HK, Bushel P, Paules R, Afshari CA. Discovery in toxicology: mediation by gene expression array technology. J Biochem Mol Toxicol 2001, 15, 231–242.
   PubMed Web of Science ®Google Scholar
• Schlaepferab IR, Hofta NR, Collinsa AC, Corleya RP, Hewittac JK, Hopferd CJ, Lessema JM, McQueenac MB, Rheeac SH, Ehringerab MA. The CHRNA5/A3/B4 Gene Cluster Variability as an Important Determinant of Early Alcohol and Tobacco Initiation in Young Adults. Biological Psychiatry 2008 63,1039–1046.
   Google Scholar
• Hossain SJ, Aoshima H, Koda H, Kiso Y. Potentiation of the ionotropic GABA receptor response by whiskey fragrance. J Agric Food Chem 2002, 50, 6828–6834.
   PubMedGoogle Scholar
• Joshi I. Ionotropic glutamate receptor expression during embryonic stem cell differentiation. Dissertation submitted to the International Graduate School of Neuroscience (IGSN), Ruhr University Bochum, 2007.
   Google Scholar
• Koda H, Hossain SJ, Kiso Y, Aoshima H. Aging of whiskey increases the potentiation of GABA(A) receptor response. J Agric Food Chem 2003, 51, 5238–5244.
   PubMedGoogle Scholar
• Krishnamoorthy M, Gerwe BA, Scharer CD, Heimburg-Molinaro J, Gregory F, Nash RJ, Arumugham J, Stewart B, Stice SL, Nash RJ. Low ethanol concentration alters CHRNA5 RNA levels during early human development. Reprod Toxicol 2010, 30, 489–492.
   PubMedGoogle Scholar
• Krishnamoorthy M, Gerwe BA, Heimburg-Molinaro J, Nash RJ, Arumugham J, Eilertson CD, Stice SL, Nash RJ. Ethanol alters cell cycle gene expression in human embryonic stem cells. Journal of Pediatric Biochemistry 2010, 1, 201–208.
   Google Scholar
• Lyle R, Gehrig C, Neergaard-Henrichsen C, Deutsch S, Antonarakis SE. Gene expression from the aneuploid chromosome in a trisomy mouse model of down syndrome. Genome Res 2004, 14, 1268–1274.
   PubMed Web of Science ®Google Scholar
• Martin D, Savage DD, Swartzwelder HS. Effects of prenatal ethanol exposure on hippocampal ionotropic-quisqualate and kainate receptors. Alcohol Clin Exp Res 1992, 16, 816–821.
   Google Scholar
• McBride WJ, Kerns RT, Rodd ZA, Strother WN, Edenberg HJ, Hashimoto JG, Wiren KM, Miles MF. Alcohol effects on central nervous system gene expression in genetic animal models. Alcohol Clin Exp Res 2005, 29, 167–175.
   Google Scholar
• Mitsuyama H, Little KY, Sieghart W, Devaud LL, Morrow AL. GABA(A) receptor alpha1, alpha4, and beta3 subunit mRNA and protein expression in the frontal cortex of human alcoholics. Alcohol Clin Exp Res 1998, 22, 815–822.
   Google Scholar
• Mootha VK, Lindgren CM, Eriksson KF, Subramanian A, Sihag S, Lehar J, Puigserver P, Carlsson E, Ridderstråle M, Laurila E, Houstis N, Daly MJ, Patterson N, Mesirov JP, Golub TR, Tamayo P, Spiegelman B, Lander ES, Hirschhorn JN, Altshuler D, Groop LC. PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet 2003, 34, 267–273.
   PubMed Web of Science ®Google Scholar
• Nash RJ, Heimburg-Molinaro J, Nash RJ. Heparin binding epidermal growth factor-like growth factor reduces ethanol-induced apoptosis and differentiation in human embryonic stem cells. Growth Factors 2009, 27, 362–369.
   PubMed Web of Science ®Google Scholar
• Netzeband JG, Trotter C, Caguioa JN, Gruol DL. Chronic ethanol exposure enhances AMPA-elicited Ca2+ signals in the somatic and dendritic regions of cerebellar Purkinje neurons. Neurochem Int 1999, 35, 163–174.
   Google Scholar
• Netzeband JG, Trotter C, Parsons KL, Gruol DL. Chronic ethanol treatment alters AMPA-induced calcium signals in developing Purkinje neurons. Brain Res 1999, 826, 270–280.
   Google Scholar
• Reich M, Liefeld T, Gould J, Lerner J, Tamayo P, Mesirov JP. GenePattern 2.0. Nat Genet 2006, 38, 500–501.
   PubMed Web of Science ®Google Scholar
• Roberto M, Madamba SG, Moore SD, Tallent MK, Siggins GR. Ethanol increases GABAergic transmission at both pre- and postsynaptic sites in rat central amygdala neurons. Proc Natl Acad Sci USA 2003, 100, 2053–2058.
   PubMed Web of Science ®Google Scholar
• Saccone NL, Wang JC, Breslau N, Johnson EO, Hatsukami D, Saccone SF, Grucza RA, Sun L, Duan W, Budde J, Culverhouse RC, Fox L, Hinrichs AL, Steinbach JH, Wu M, Rice JP, Goate AM, Bierut LJ. The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans. Cancer Res 2009, 69, 6848–6856.
   PubMed Web of Science ®Google Scholar
• Sanger DJ. Ionotropic receptors and stimulus effects of drugs: whisky and water or vodka on the rocks? Commentary on Grant, “Emerging neurochemical in the action of ethanol at ligand-gated ion channels”. Behav Pharmacol 1994, 5, 405–406.
   Google Scholar
• Schlaepfer IR, Hoft NR, Collins AC, Corley RP, Hewitt JK, Hopfer CJ, Lessem JM, McQueen MB, Rhee SH, Ehringer MA. The CHRNA5/A3/B4 gene cluster variability as an important determinant of early alcohol and tobacco initiation in young adults. Biol Psychiatry 2008, 63, 1039–1046.
   PubMed Web of Science ®Google Scholar
• Shimron-Abarbanell D, Erdmann J, Vogt IR, Bryant SP, Spurr NK, Knapp M, Propping P, Nöthen MM. Human 5-HT5A receptor gene: systematic screening for DNA sequence variation and linkage mapping on chromosome 7q34-q36 using a polymorphism in the 5′ untranslated region. Biochem Biophys Res Commun 1997, 233, 6–9.
   PubMedGoogle Scholar
• Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA, Paulovich A, Pomeroy SL, Golub TR, Lander ES, Mesirov JP. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA 2005, 102, 15545–15550.
   PubMed Web of Science ®Google Scholar
• Tabakoff B, Saba L, Printz M, Flodman P, Hodgkinson C, Goldman D, Koob G, Richardson HN, Kechris K, Bell RL, Hübner N, Heinig M, Pravenec M, Mangion J, Legault L, Dongier M, Conigrave KM, Whitfield JB, Saunders J, Grant B, Hoffman PL. Genetical genomic determinants of alcohol consumption in rats and humans. BMC Biol 2009, 7, 70.
   PubMed Web of Science ®Google Scholar
• Townsend JP, Cavalieri D, Hartl DL. Population genetic variation in genome-wide gene expression. Mol Biol Evol 2003, 20, 955–963.
   Google Scholar
• Tusher VG, Tibshirani R, Chu G. Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci USA 2001, 98, 5116–5121.
   PubMed Web of Science ®Google Scholar
• Wang JC, Grucza R, Cruchaga C, Hinrichs AL, Bertelsen S, Budde JP, Fox L, Goldstein E, Reyes O, Saccone N, Saccone S, Xuei X, Bucholz K, Kuperman S, Nurnberger J Jr, Rice JP, Schuckit M, Tischfield J, Hesselbrock V, Porjesz B, Edenberg HJ, Bierut LJ, Goate AM. Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence. Mol Psychiatry 2009, 14, 501–510.
   PubMed Web of Science ®Google Scholar
• Woodward JJ. Ionotropic glutamate receptors as sites of action for ethanol in the brain. Neurochem Int 1999, 35, 107–113.
   Google Scholar
• Worst TJ, Vrana KE. Alcohol and gene expression in the central nervous system. Alcohol Alcohol 2005, 40, 63–75.
   Google Scholar
• Yan H, Dobbie Z, Gruber SB, Markowitz S, Romans K, Giardiello FM, Kinzler KW, Vogelstein B. Small changes in expression affect predisposition to tumorigenesis. Nat Genet 2002, 30, 25–26.
   Google Scholar
• Young SZ, Bordey A. GABA’s control of stem and cancer cell proliferation in adult neural and peripheral niches. Physiology (Bethesda) 2009, 24, 171–185.
   PubMed Web of Science ®Google Scholar