References
- Duvernay MT, Filipeanu CM, Wu G. The regulatory mechanisms of export trafficking of G protein-coupled receptors. Cell Signal 2005;17:1457–65
- Conn PM, Ulloa-Aguirre A, Ito J, Janovick JA. G protein-coupled receptor trafficking in health and disease: lessons learned to prepare for therapeutic mutant rescue in vivo. Pharmacol Rev 2007;59:225–50
- Milligan G. G protein-coupled receptor dimerization: function and ligand pharmacology. Mol Pharmacol 2004;66:1–7
- Morello JP, Petäjä-Repo UE, Bichet DG, Bouvier M. Pharmacological chaperones: a new twist on receptor folding. Trends Pharmacol Sci 2000;21:466–9
- Dong C, Filipeanu CM, Duvernay MT, Wu G. Regulation of G protein-coupled receptor export trafficking. Biochim Biophys Acta 2007;1768:853–70
- Drake MT, Shenoy SK, Lefkowitz RJ. Trafficking of G protein-coupled receptors. Circ Res 2006;99:570–82
- Wolfe BL, Trejo J. Clathrin-dependent mechanisms of G protein-coupled receptor endocytosis. Traffic 2007;8:462–70
- Hanyaloglu AC, von Zastrow M. Regulation of GPCRs by endocytic membrane trafficking and its potential implications. Annu Rev Pharmacol Toxicol 2008;48:537–68
- Kenakin T. Functional selectivity and biased receptor signaling. J Pharmacol Exp Ther 2011;336:296–302
- Raote I, Bhattacharyya S, Panicker MM. Functional selectivity in serotonin receptor 2A (5-HT2A) endocytosis, recycling, and phosphorylation. Mol Pharmacol 2013;83:42–50
- Arttamangkul S, Quillinan N, Low MJ, et al. Differential activation and trafficking of micro-opioid receptors in brain slices. Mol Pharmacol 2008;74:972–9
- Koch T, Höllt V. Role of receptor internalization in opioid tolerance and dependence. Pharmacol Ther 2008;117:199–206
- Lohse MJ, Benovic JL, Caron MG, Lefkowitz RJ. Multiple pathways of rapid beta 2-adrenergic receptor desensitization. Delineation with specific inhibitors. J Biol Chem 1990;265:3202–11
- Green SA, Liggett SB. A proline-rich region of the third intracellular loop imparts phenotypic beta 1-versus beta 2-adrenergic receptor coupling and sequestration. J Biol Chem 1994;269:26215–19
- Giepmans BN, Adams SR, Ellisman MH, Tsien RY. The fluorescent toolbox for assessing protein location and function. Science 2006;312:217–24
- Salahpour A, Angers S, Mercier JF, et al. Homodimerization of the beta2-adrenergic receptor as a prerequisite for cell surface targeting. J Biol Chem 2004;279:33390–7
- Fichter KM, Flajolet M, Greengard P, Vu TQ. Kinetics of G-protein-coupled receptor endosomal trafficking pathways revealed by single quantum dots. Proc Natl Acad Sci U S A 2010;107:18658–63
- Michel MC, Wieland T, Tsujimoto G. How reliable are G-protein-coupled receptor antibodies? Naunyn-Schmiedeberg's Arch Pharmacol 2009;379:385–8
- Hurley WL, Finkelstein E, Holst BD. Identification of surface proteins on bovine leukocytes by a biotin-avidin protein blotting technique. J Immunol Methods 1985;85:195–202
- Elia G. Cell surface protein biotinylation for SDS-PAGE analysis. Methods Mol Biol 2012;869:361–72
- Brizzard B. Epitope tagging. Biotechniques 2008;44:693–5
- Shimomura O. Structure of the chromophore of aequorea green fluorescent protein. FEBS Lett 1979;104:220–2
- Fisher GW, Adler SA, Fuhrman MH, et al. Detection and quantification of beta2AR internalization in living cells using FAP-based biosensor technology. J Biomol Screen 2010;15:703–9
- Salahpour A, Barak LS. Visualizing receptor endocytosis and trafficking. Methods Mol Biol 2011;756:311–23
- Black CB, Duensing TD, Trinkle LS, Dunlay RT. Cell-based screening using high-throughput flow cytometry. Assay Drug Dev Technol 2011;9:13–20
- Takeda Y, Yano Y, Matsuzaki K. High-throughput analysis of ligand-induced internalization of β2-adrenoceptors using the coiled-coil tag-probe method. Anal Chem 2012;84:1754–9
- Wu Y, Tapia PH, Fisher GW, et al. Discovery of regulators of receptor internalization with high-throughput flow cytometry. Mol Pharmacol 2012;82:645–57
- Keppler A, Pick H, Arrivoli C, et al. Labeling of fusion proteins with synthetic fluorophores in live cells. Proc Natl Acad Sci U S A 2004;101:9955–9
- Gautier A, Juillerat A, Heinis C, et al. An engineered protein tag for multiprotein labeling in living cells. Chem Biol 2008;15:128–36
- Zwier JM, Roux T, Cottet M, et al. A fluorescent ligand-binding alternative using Tag-lite® technology. J Biomol Screen 2010;15:1248–59
- Maurel D, Comps-Agrar L, Brock C, et al. Cell-surface protein-protein interaction analysis with time-resolved FRET and snap-tag technologies: application to GPCR oligomerization. Nat Methods 2008;5:561–7
- Hammer MM, Wehrman TS, Blau HM. A novel enzyme complementation-based assay for monitoring g-protein-coupled receptor internalization. FASEB J 2007;21:3827–34
- Ashby MC, Ibaraki K, Henley JM. It's green outside: tracking cell surface proteins with pH-sensitive GFP. Trends Neurosci 2004;27:257–61
- Yudowski GA, von Zastrow M. Investigating G protein-coupled receptor endocytosis and trafficking by TIR-FM. Methods Mol Biol 2011;756:325–32
- Conway R. Quantification of G-protein coupled receptor internalization using G-protein coupled receptor-green fluorescent protein conjugates with the ArrayscanTM high-content screening system. J Biomol Screen 1999;4:75–86
- Rausch O. High content cellular screening. Curr Opin Chem Biol 2006;10:316–20