Down-regulation of TGF-b1, TGF-b receptor 2, and TGF-b-associated microRNAs, miR-20a and miR-21, in skin lesions of sulfur mustard-exposed Iranian war veterans

References

• Kehe K, Szinicz L. Medical aspects of sulphur mustard poisoning. Toxicology 2005;214:198–209
   PubMed Web of Science ®Google Scholar
• Somani SM. Chemical warfare agents. 1st ed. Academic Press; San Diego, 1992. 443 p. (20 May 1992)
   Google Scholar
• Skoet R, Zachariae R, Agner T. Contact dermatitis and quality of life: a structured review of the literature. Br J Dermatol 2003;149:452–6
   PubMed Web of Science ®Google Scholar
• Wattana M, Bey T. Mustard gas or sulfur mustard: an old chemical agent as a new terrorist threat. Prehosp Disaster Med 2009;24:19–29; discussion 30–1
   PubMedGoogle Scholar
• Wu MY, Hill CS. Tgf-beta superfamily signaling in embryonic development and homeostasis. Dev Cell 2009;16:329–43
   PubMed Web of Science ®Google Scholar
• Shi Y, Massague J. Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 2003;113:685–700
   PubMed Web of Science ®Google Scholar
• Wrighton KH, Lin X, Feng XH. Phospho-control of TGF-beta superfamily signaling. Cell Res 2009;19:8–20
   PubMed Web of Science ®Google Scholar
• Massague J, Chen YG. Controlling TGF-beta signaling. Genes Dev 2000;14:627–44
   PubMed Web of Science ®Google Scholar
• Derynck R, Zhang Y, Feng XH. Smads: transcriptional activators of TGF-beta responses. Cell 1998;95:737–40
   PubMed Web of Science ®Google Scholar
• Eder IE, Stenzl A, Hobisch A, et al. Expression of transforming growth factors beta-1, beta 2 and beta 3 in human bladder carcinomas. Br J Cancer 1997;75:1753–60
   PubMed Web of Science ®Google Scholar
• He L, Hannon GJ. MicroRNAs: small RNAs with a big role in gene regulation. Nat Rev Genet 2004;5:522–31
   PubMed Web of Science ®Google Scholar
• Allegra A, Alonci A, Campo S, et al. Circulating microRNAs: new biomarkers in diagnosis, prognosis and treatment of cancer (review). Int J Oncol 2012;41:1897–912
   PubMed Web of Science ®Google Scholar
• Si ML, Zhu S, Wu H, et al. miR-21-mediated tumor growth. Oncogene 2007;26:2799–803
   PubMed Web of Science ®Google Scholar
• Schmierer B, Hill CS. TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility. Nat Rev Mol Cell Biol 2007;8:970–82
   PubMed Web of Science ®Google Scholar
• Davis BN, Hilyard AC, Lagna G, et al. SMAD proteins control DROSHA-mediated microRNA maturation. Nature 2008;454:56–61
   PubMed Web of Science ®Google Scholar
• Mendell JT. miRiad roles for the miR-17-92 cluster in development and disease. Cell 2008;133:217–22
   PubMed Web of Science ®Google Scholar
• Schultz N, Marenstein DR, De Angelis DA, et al. Off-target effects dominate a large-scale RNAi screen for modulators of the TGF-beta pathway and reveal microRNA regulation of TGFBR2. Silence 2011;2:3
   PubMedGoogle Scholar
• Balali-Mood M, Hefazi M, Mahmoudi M, et al. Long-term complications of sulphur mustard poisoning in severely intoxicated Iranian veterans. Fundam Clin Pharmacol 2005;19:713–21
   PubMed Web of Science ®Google Scholar
• Mirzamani MS, Nourani MR, Imani Fooladi AA, et al. Increased expression of transforming growth factor-beta and receptors in primary human airway fibroblasts from chemical inhalation patients. Iran J Allergy Asthma Immunol 2013;12:144–52
   PubMed Web of Science ®Google Scholar
• Aghanouri R, Ghanei M, Aslani J, et al. Fibrogenic cytokine levels in bronchoalveolar lavage aspirates 15 years after exposure to sulfur mustard. Am J Physiol Lung Cell Mol Physiol 2004;287:L1160–4
   PubMed Web of Science ®Google Scholar
• Khaheshi I, Keshavarz S, Imani Fooladi AA, et al. Loss of expression of TGF-betas and their receptors in chronic skin lesions induced by sulfur mustard as compared with chronic contact dermatitis patients. BMC Dermatol 2011;11:2
   PubMedGoogle Scholar
• Panahi Y, Davoudi SM, Beiraghdar F, et al. Relationship between levels of IFNgamma, TNFalpha, and TGFbeta and pruritus in sulfur mustard-exposed veterans. J Immunotoxicol 2013;10:173–7
   PubMed Web of Science ®Google Scholar
• Zarin AA, Behmanesh M, Tavallaei M, et al. Overexpression of transforming growth factor (TGF)-beta1 and TGF-beta3 genes in lung of toxic-inhaled patients. Exp Lung Res 2010;36:284–91
   PubMed Web of Science ®Google Scholar
• Miyazono K, ten Dijke P, Heldin CH. TGF-beta signaling by Smad proteins. Adv Immunol 2000;75:115–57
   PubMed Web of Science ®Google Scholar
• Sabourin CL, Petrali JP, Casillas RP. Alterations in inflammatory cytokine gene expression in sulfur mustard-exposed mouse skin. J Biochem Mol Toxicol 2000;14:291–302
   PubMed Web of Science ®Google Scholar
• Ricketts KM, Santai CT, France JA, et al. Inflammatory cytokine response in sulfur mustard-exposed mouse skin. J Appl Toxicol 2000;20:S73–6
   PubMed Web of Science ®Google Scholar
• Monfared H, Ziaee SA, Hashemitabar M, et al. Co-regulated expression of TGF-beta Variants and miR-21 in bladder cancer. Urol J 2013;10:981–7
   PubMed Web of Science ®Google Scholar
• Ma X, Becker Buscaglia LE, Barker JR, et al. MicroRNAs in NF-kappaB signaling. J Mol Cell Biol 2011;3:159–66
   PubMed Web of Science ®Google Scholar
• Li L, Shi JY, Zhu GQ, et al. MiR-17-92 cluster regulates cell proliferation and collagen synthesis by targeting TGFB pathway in mouse palatal mesenchymal cells. J Cell Biochem 2012;113:1235–44
   PubMed Web of Science ®Google Scholar
• Dews M, Fox JL, Hultine S. The myc-miR-17–92 axis blunts TGF{beta} signaling and production of multiple TGF{beta}-dependent antiangiogenic factors. Cancer Res 2010;70:8233–46
   PubMed Web of Science ®Google Scholar
• Philippe L, Alsaleh G, Pichot A, et al. MiR-20a regulates ASK1 expression and TLR4-dependent cytokine release in rheumatoid fibroblast-like synoviocytes. Ann Rheum Dis 2013;72:1071–9
   PubMed Web of Science ®Google Scholar
• Philippe L, Alsaleh G, Bahram S, et al. The miR-17 ∼ 92 cluster: a key player in the control of inflammation during rheumatoid arthritis. Front Immunol 2013;4:70
   Google Scholar
• Reinhard J. A neuronal receptor for botulinum toxin. Science 2006;312:540–1
   PubMed Web of Science ®Google Scholar
• Dong M, Yeh F, Tepp WH, et al. SV2 is the protein receptor for botulinum neurotoxin A. Science 2006;312:592–6
   PubMed Web of Science ®Google Scholar
• Cohen JE, Lee PR, Chen S, et al. MicroRNA regulation of homeostatic synaptic plasticity. Proc Natl Acad Sci USA 2011;108:11650–5
   PubMed Web of Science ®Google Scholar