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Research Article

Experimental Artifacts and the Analysis of Ligand Binding Data: Results of a Computer Simulation

Pages 249-259 | Published online: 26 Sep 2008

References

  • Munson P. J., Rodbard D. LIGAND: A Versatile Computerized Approach for Characterizartion of Ligand-Binding Systems. Anal. Biochem. 1980; 107: 220–239
  • Munson P. J., Rodbard D. Computer Modeling of Several Ligands to Multiple Receptors. Endocrinology 1979; 105: 1377–1381
  • A listing of the computer program used to simulate these artifacts is available from the author upon request. It is written in BASIC for the DEC System-10 computer
  • Boeynaems J. M., Dumont J. E. Quantitative Analysis of the Binding of Ligands to their Receptors. J. Cycl. Neucleotide Research 1975; 1: 123–132
  • Boeynaems J. M., Dumont J. E. Outlines of Receptor Theory Elsevier North-Holland. Amsterdam 1980
  • Reimann E. M., Soloff M. S. The Effect of Radioactive Contaminants on the Estimation of Binding Parameters by Scatchard Analysis. Biochem. Biophys. Acta. 1978; 533: 130–139
  • Feldman H. A. ldquo;Mathematical Theory of Complex Ligand-binding Systems at Equilibrium.”. Anal. Biochem. 1972; 48: 317–338

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