Structure and Location of a Gabaa Receptor Complex in the Central Nervous System

References

• MÖHler H., Okada T. Demonstration of benzodiazepine, receptors in the central nervous system. Science 1977; 198: 849–851
   PubMed Web of Science ®Google Scholar
• Squires R. F., Braestrup C. Benzodiazepine receptors in rat brain. Nature 1977; 266: 732–734
   PubMed Web of Science ®Google Scholar
• Haefely W., Polc P. Electrophysiological studies on the interactions of anxiolytic drugs with GABAergic mechanisms. Benzodiazepine/GABA Receptors and Chloride Channels: Structural and Functional Properties, R. W. 01Sen, J. C. Venter. Alan R. Liss, New York, in press
   Google Scholar
• Haefely W. Actions and interactions of benzodiazepine agonists and antagonists at GABAergic synapses. Actions and Inter-actions of GABA and Benzodiazepines, N. G. Bowery. Raven Press, New York 1984; 263–285
   Google Scholar
• Braestrup C., Schmiechen R., Nielsen M., Petersen E. N. Interaction of convulsive ligands with benzodiazepine receptors. Science 1982; 216: 1241–1243
   PubMed Web of Science ®Google Scholar
• HÄRing P., StÄHli C., Schoch P., Takacs B., Staehelin T., MÖHler H. Monoclonal antibodies reveal structural homogeneity of γ-aminobutyric acid/benzodiazepine receptors in different brain areas. Proc.Natl.Acad.Sci.USA 1985; 82: 4837–4841
   PubMedGoogle Scholar
• MÖHler H., Schoch P., Richards J. G., HÄRing P., Takacs B., StÄHli C. Monoclonal antibodies as probes for studying the structure and location of the GABA receptor/benzodiazepine receptor/chloride channel complex. Benzodiaezepine/GABA Receptors and Chloride Channels: Structural and Functional Properties, R. W. Olsen, J. C. Venter. Alan R. Liss, New York 1986; 285–297
   Google Scholar
• MÖHler H., Battersby M. K., Richards J. G. Benzodiazepine receptor protein identified and visualized in brain tissue by a photoaffinity label. Proc.Natl.Acad.Sci.USA 1980; 77: 1666–1670
   PubMed Web of Science ®Google Scholar
• Sigel E., Barnard E. A. A γ-aminobutyric acid/benzodiazepine receptor complex of bovine cerebral cortex: purification and partial characterization. J.Biol.Chem. 1983; 258: 6965–6971
   PubMed Web of Science ®Google Scholar
• Schoch P., HÄRing P., Takacs B., StÄHli C., MÖHler H. A GABA/benzodiazepine receptor from bovine brain: purification, reconstitution and immunological characterization. J.Recept.Res. 1984; 4: 189–200
   PubMed Web of Science ®Google Scholar
• Schoch P., Richards J. G., HÄRing P., Takacs B., StÄHli C., Staehelin T., Haefely W., MÖHler H. Co-localization of GABA receptors and benzodiazepine receptors in the brain shown by monoclonal antibodies. Nature 1985; 314: 168–171
   PubMed Web of Science ®Google Scholar
• Chang L.-R., Barnard E. A. The benzodiazepine GABA receptor complex: molecular size in brain synaptic membranes and in solution, J. Neurochem. 1982; 39: 1507–1518
   PubMedGoogle Scholar
• Sieghart W., Karobath M. Molecular heterogeneity of benzodiazepine receptors. Nature 1980; 286: 285–287
   PubMed Web of Science ®Google Scholar
• Casalotti S. O., Stephenson F. A., Barnard E. A. Separate subunits for agonist and benzodiazepine binding in the γ-amino-butyric acida receptor oligomer, J. Biol. Chem. 1986; 261: 15013–15016
   Google Scholar
• Sigel E., Mamalaki C., Barnard E. A. Reconstitution of the purified γ-aminobutyric acid-benzodiazepine receptor complex from bovine cerebral cortex into phospholipid vesicles. Neurosci. Lett. 1985; 61: 165–170
   PubMedGoogle Scholar
• Sweetman P. M., Tallman J. F. Regional difference in brain benzodiazepine receptor carbohydrates, J. Pharm. Exp. Ther. 1986; 29: 299–306
   Google Scholar
• Richards J. G., MÖHler H., Haefely W. Mapping benzodiazepine receptors in the CNS by radiohistochemistry and immuno-histochemistry. Neurology and Neurobiology Vol. 16, Neuro-histochemistry, Modern Methods and Applications, P. Panula, H. PÄIvÄRinta, S. Soinita. Alan R. Liss, New York 1986; 629–677
   Google Scholar
• Richards J. G., Schoch P., HÄRing P., Takacs B., MÖHler H. Resilving GABAA/benzodiazepine receptors: cellular and subcellular localization in the CNS with monoclonal antibodies. J. Neurosci.
   Google Scholar
• Richards J. G., MÖHler H. Benzodiazepine receptors. Neuropharmacology 1984; 23: 233–242
   PubMed Web of Science ®Google Scholar
• Haefely W., Polc P. Electrophysiological studies on the interaction of anxiolytic drugs with GABAergic mechanisms. Anxiolytics: Neurochemical, Behavioural and Clinical Perspective, J. B. Malick, S. J. Enna, H. I. Yamamura. Raven Press, New York 1983; 113–146
   Google Scholar
• Haefely W., Kyburz E., Gerecke M., MÖHler H. Recent advances in the molecular pharmacology of benzodiazepine receptors and in the structure activity relationships of their agonists and antagonists. Advances in Drug Research 1985; 14: 165–322
   Google Scholar
• Nghiem H. O., Cartand J., Dubrenil C., Kordeli C., Buttin C., Changeux J.-P. Production and characterization of a monoclonal antibody directed against the 43, 000- dalton v1 polypeptide from Torpedo marmorata electric organ, Proc. Natl. Acad. Sci. USA 1983; 80: 6403–6407
   PubMed Web of Science ®Google Scholar
• Sealock R., Wray B. E., Froehner S. C. Ultrastructural localization of the Mr 43, 000 protein and the acetylcholine receptor in Torpedo postsynaptic membranes using monoclonal antibodies, J. Cell Biol. 1984; 98: 2239–2244
   PubMed Web of Science ®Google Scholar
• Alho H., Costa E., Ferrero P., Fujimoto M., Cosenza-Murphy D., Guidotti A. Diazepam binding inhibitor (DBI): a neuropeptide located in selected neuronal populations of rat brain. Science 1985; 229: 179–182
   PubMedGoogle Scholar
• Schoch P., Richards J. G., HÄRing P., Takacs B., MÖHler H. Structural analysis and localization of GABA/benzo-diazepine/TBPS-receptor complex using monoclonal antibodies. Advances in Biochemical Psychophamacology Vol. 41, G. Biggio, E. Costa. Raven Press, New York 1986; 11–20
   Google Scholar