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Research Article

Quantitative Comparison of Bromoacetylated Derivatives of Alprenolol and Pindolol on Beta-Adrenergic Receptor Binding and Mobility in S49 Cells

Pages 385-403 | Published online: 26 Sep 2008

References

  • Atlas D. βAdrenergic receptors. Methods in Enzymology 1977; 46: 591–601
  • Neve K. A., Molinoff P. B. Turnover of β1 ‐ and β2‐adrenergic receptors after down‐regulation or irreversible blockade. Mol. Pharmacol. 1986; 30: 104–111
  • Pitha J., Zjawiony J., Nasrin N., Lefkowitz R. J., Caron M. G. Potent β‐adrenergic antagonist possessing chemically reactive group. Life Sci. 1980; 27: 1791–1798
  • Pitha J., Buchowiecki W., Milecki J., Kusiak J. W. Affinity labels for β‐adrenoceptors: preparation and properties of alkylating β‐blockers derived from indole. J. Med. Chem. 1987; 30: 612–615
  • Homburger V., Gozlan H., Bouhelal R., Lucas M., Bockaert J. lrreversible blockade of β‐adrenergic receptors with a bromoacetyl derivative of pindolol. Naunyn‐Schmiedeberg's Arch. Pharmacol. 1985; 328: 279–287
  • Chorev M., Feigenbaum A., Keenan A., Gilon C., Levitzki A. N‐bromoacetyl‐aminocyanopindolol: a highly potent β‐adrenergic affinity label blocks irreversibly a nonprotein component tightly associated with the receptor. Eur. J. Biochem. 1985; 146: 9–14
  • Box R., Staehelin M. Bromoacetylalprenololmenthane binding to β‐receptors modulates the rate of hormone‐induced internalization but not desensitization in S49 cells. FEBS Lett. 1987; 214: 323–326
  • Mahan L. C., Insel P. A. Expression of β‐adrenergic receptors in synchronous and asynchronous S49 lymphoma cells (I + II). Mol. Pharmacol. 1986; 29: 7–22
  • Jasper R., Motulsky H., Insel P. Characterization of a bromoacetylated derivative of pindolol as a high affinity, irreversible β‐adrenergic antagonist in cultured cells. J. Pharmacol. Exp. Ther. 1988; 244: 820–824
  • Hertel C., Müller P., Portenier M., Staehelin M. Determination of the desensitization of β‐adrenergic receptors by 3H‐CGP‐12177. Biochem. J. 1983; 216: 669–674
  • Staehelin M., Müller P., Portenier M., Harris A. β‐Adrenergic receptors and adenylate cyclase activity in murine lymphoid cell lines. J. Cyclic Nucleotide and Prot. Phosphoryl. Res. 1985; 10: 55–64
  • Havel R. J., Eder H. A., Bragdon J. H. The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. J. Clin. Invest. 1955; 34: 1345–1353
  • Laubscher A., Pletscher A. Shape change and uptake of 5‐hydroxytryptamine in human blood platelets: action of neuropsychotropic drugs. Life Sci. 1979; 24: 1833–1840
  • Bilheimer D., Eisenberg S., Levy R. The metabolism of very low density lipoprotein proteins. BBA 1972; 260: 212–221
  • Mahan L., Motulsky H., Insel P. Do agonists promote rapid internalization of β‐adrenergic receptors?. Proc. Natl. Acad. Sci. USA 1985; 82: 6566–6570
  • Bar‐Sinai A., Aldouby Y., Chorev M., Levitzki A. Association of turkey erythrocyte β‐adrenoceptors with a specific lipid component. EMBO J. 1986; 5: 1175–1180
  • Maturo J., Hollenberg M. Insulin receptor: Interaction with non‐receptor glycoprotein from liver cell membranes. Proc. Natl. Acad. Sci. USA 1978; 75: 3070–3074
  • Schlessinger J., Elson E., Webb W., Yahara I., Rutishauser U., Edelman G. Receptor diffusion on cell surfaces modulated by locally bound concanavalin A. Proc. Natl. Acad. Sci. USA 1977; 74: 1110–1114
  • Muntz K., Calianos T., Buja L., Willerson J., Bernatowicz M., Homcy C., Graham R. Electron microscopic localization of the β‐adrenergic receptor using a ferritin‐alprenolol probe. Mol. Pharmacol. 1988; 34: 444–451

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