6
Views
3
CrossRef citations to date
0
Altmetric
Research Article

Guanylpirenzepine Distinguishes Between Neuronal m1 and m4 Muscarinic Receptor Subtypes

, , , &
Pages 81-96 | Published online: 26 Sep 2008

References

  • Hammer R., Giachetti A. Muscarinic receptors subtypes M1 and M2: biochemical and functional characterization. Life Sci. 1982; 31: 2991–2998
  • Hammer R., Giraldo E., Schiavi G. B., Monferini E., Ladinsky H. Binding profile of a novel cardioselective muscarine receptor antagonist, AF-DX 116, to membranes of peripheral tissues and brain in the rat. Life Sci. 1986; 38: 1653–1662
  • Giraldo E., Martos F., Gomez A., Garcia A., Viganò M. A., Ladinsky H., Sanchez de La Cuesta F. Characterization of muscarinic receptor subtypes in human tissues. Life Sci. 1988; 43: 1507–1515
  • Monferini E., Giraldo E., Ladinsky H. Characterization of the muscarinic receptor subtypes in the rat urinary bladder. Eur. J. Pharmacol. 1988; 147: 453–458
  • Giraldo E., Hammer R., Ladinsky H. Distribution of muscarinic receptor subtypes in rat brain as determined in binding studies with AF-DX 116 and pirenzepine. Life Sci. 1987; 40: 833–840
  • Giachetti A., Micheletti R., Montagna E. Cardioselective profile of AF-DX 116, a muscarinic M2 receptor antagonist. Life Sci. 1986; 38: 1663–1672
  • Doods H. N., Mathy M. J., Davidesko D., van Charldorp K. J., de Jonge A., van Zwieten P. A. Selectivity of muscarinic antagonists in radioligand and in vivo experiments for the putative M1, M2 and M3 receptors. J. Pharmacol. Exp. Ther. 1987; 242: 257–262
  • Kubo T., Fukuda K., Mikami A., Maeda A., Takahashi H., Mishina M., Haga T., Haga K., Ichiyama A., Kangawa K., Kojima M., Matsuo H., Hirose T., Numa S. Cloning, sequencing and expression of complementary DNA encoding the muscarinic acetylcholine receptor. Nature 1986; 323: 411–416
  • Kubo T., Maeda A., Sugimoto K., Akiba I., Mikami A., Takahashi H., Haga T., Haga K., Ichiyama A., Kangawa K., Matsuo H., Hirose T., Numa S. Primary structure of porcine cardiac muscarinic acetylcholine receptor deduced from DNA sequence. FEES Lett. 1986; 209: 367–372
  • Buckley N., Bonner T. I., Brann M. Localization of a family of muscarinic receptor mRNAs in rat brain. J. Neurosci. 1988; 8: 4646–4652
  • Bonner T. I., Buckley N. J., Young A. C., Brann M. R. Identification of a family of muscarinic acetylcholine receptor genes. Science 1987; 237: 527–532
  • Buckley N. J., Bonner T. I., Buckley C. M., Brann M. R. Antagonist binding properties of five cloned muscarinic receptors expressed in CHO-K1 cells. Mol. Pharmacol. 1989; 35: 469–476
  • Bonner T. I., Young A. C., Brann M. R., Buckley N. J. Cloning and expression of the human and rat m5 muscarinic receptor genes. Neuron 1988; 1: 403–410
  • The current classification for muscarinic receptor subtypes has been recently reviewed and the recommended nomenclature is reported. Trends Pharmacol Sci. 1989; 10, (Suppl. Subtypes Muscarinic Receptors IV)
  • European Patent Application. 309422, 1989, to Istituto De Angeli
  • Giraldo E., Micheletti R., Montagna E., Giachetti A., Viganò M. A., Ladinsky H., Melchiorre C. Binding and functional characterization of the cardioselective muscarinic antagonist methoctramine. J.Pharmacol. Exp. Ther. 1987; 244: 1016–1020
  • Munson P. J., Rodbard D. LIGAND: a versatile computerized approach for characterization of ligand-binding system. Anal. Biochem. 1980; 107: 220–239
  • Munson P. J., Rodbard D. Computerized analysis of ligand binding data: basic principles and recent developments. Computers and Endocrinology, D. Rodbard, G. Forte. Raven Press, NY 1984; 117–145
  • Wamsley J. K., Gehlert D. R., Roeske W. R., Yamamura H. I. Muscarinic antagonist binding site heterogeneity as evidenced by autoradiography after directly labeling with 3H-QNB and 3H-Pirenzepine. Life Sci. 1984; 34: 1395–1402
  • Cortes R., Palacios J. M. Muscarinic cholinergic receptor subtypes in the rat brain. 1.Quantitative autoradiographic studies. Brain Res. 1986; 362: 227–238
  • Cortes R., Probst A., Tobler H. J., Palacios J. M. Muscarinic cholinergic receptor subtypes in the human brain. 2. Quantitative autoradiographic studies. Brain Res. 1986; 362: 239–253
  • Mash D. C., Potter L. T. Autoradiographic localization of M1 and M2 muscarine receptors in the rat brain. Neurosci. 1986; 19: 551–564
  • Spencer D. G., Horvath E., Traber J. Direct autoradiographic determination of M1 and M2 muscarinic acetylcholine receptor distribution in rat brain: relation to cholinergic nuclei and projections. Brain Res. 1986; 380: 59–68

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.