6
Views
16
CrossRef citations to date
0
Altmetric
Research Article

Identification of the Multidrug Resistance-Related Membrane Glycoprotein as an Acceptor for Cyclosporine

, , &
Pages 675-686 | Published online: 26 Sep 2008

References

  • Pastan I., Gottesman M. Multiple-drug resistance in human cancer. N. Engl. J. Med. 1987; 316: 1388–1392
  • Bradley G., Juranka P., Ling V. Mechanism of multidrug resistance. Biochem. Biophys. Acta 1988; 948: 87–128
  • Chan H. S. L., Bradley G., Thorner P., Haddad G., Gallie B. L., Ling V. A sensitive method for immunocytochemical detection of P-glycoprotein in multidrug-resistant human ovarian carcinoma cell lines. Lab. Invest 1988; 59: 870–875
  • Ling V. Does P-glycoprotein predict response to chemotherapy?. J. Natl. Cancer Inst. 1989; 81: 84–85
  • Ling V., Thompson L. H. Reduced permeability in CHO cells as a mechanism of resistance to colchicine. J. Cell. Physiol. 1973; 83: 103–116
  • Kartner N., Riordan J., Ling V. Cell surface P-glycoprotein associated with multidrug resistance in mammalian cell lines. Science (Wash. D.C.) 1983; 221: 1285–1287
  • Gottesman M., Pastan I. The multidrug transporter, a double-edged sword. J. Biol. Chem. 1988; 263: 12163–12166
  • Gottesman M., Pastan I. Resistance to multiple chemotherapeutic agents in human cancer cells. Trends Pharmacol. Sci. 1988; 9: 54–58
  • Gros P., Croop J., Housman D. Mammalian multidrug resistance gene: complete cDNA sequence indicates strong homology to bacterial transport proteins. Cell 1986; 47: 371–380
  • Ueda K., Cardarelli C., Gottesman M., Pastan I. Expression of a full-length cDNA for the human MDR1 gene confers resistance to colchicine, doxorubicin, and vinblastine. Proc. Natl. Acad. Sci. USA 1987; 84: 3004–3008
  • Choi K., Chen C. J., Kriegler M., Ronnison I. An altered pattern of cross-resistance in multidrug-resistant human cells results from spontaneous mutations in the mdr1 (P-glycoprotein) gene. Cell 1988; 53: 519–529
  • Endicott J., Ling V. The biochemistry of P-glycoprotein-mediated multidrug resistance. Annu. Rev. Biochem. 1989; 58: 137–171
  • Twentyman P., Fox N., White D. Cyclosporin A and its analogues as modifiers of adriamycin and vincristine resistance in a multi-drug resistant human lung cancer cell line. Br. J. Cancer 1987; 56: 55–57
  • Goldberg H., Ling V., Wong P., Skorecki K. Reduced cyclosporin accumulation in multi-drug resistant cells. Biochem. Biophys. Res. Commun. 1988; 152: 552–558
  • Kartner N., Evernden-Porelle D., Bradley G., Ling V. Detection of P-glycoprotein in multidrug-resistant cell lines by monoclonal antibodies. Nature (Lond.) 1985; 316: 820–823
  • Handschumacher R., Harding M., Rice J., Drugge R. Cyclophilin: a specific cytosolic binding protein for cyclosporin A. Science (Wash. D.C.) 1984; 226: 544–547
  • Quesniaux V. F. J., Schreier M. H., Wenger R. M., Hiestand P. C., Harding M. W., Van Regenmortel M. H.V. Molecular characteristics of cyclophilin-cyclosporine interaction. Transplantation 1988; 46: 23S–27S
  • Cornwell M., Safa A., Felsted R., Pastan I. Membrane vesicles from multidrug-resistant human cancer cells contain a specific 150- to 170-kDa protein detected by photoaffinity labeling. Proc. Natl. Acad. Sci. USA 1986; 83: 3847–3850
  • Cornwell M. M., Pastan I., Gottesman M. M. Certain calcium channel blockers bind specifically to multidrug-resistant human KB carcinoma vesicles and inhibit drug binding to P-glycoprotein. J. Biol. Chem. 1987; 262: 2166–2170
  • Safa A. R., Glover C. J., Sewell J. L., Biedler M. B., Felsted R. L. Identification of the multidrug resistance-related membrane glycoprotein as an acceptor for calcium channel blockers. J. Biol. Chem. 1987; 262: 7884–7888
  • Cornwell M., Tsudo T., Gottesman M., Pastan I. ATP binding properties of P-glycoprotein from multidrug-resistant KB cells. FASEB J. 1987; 1: 51–54
  • Twentyman P. R. A possible role for cyclosporins in cancer chemotherapy. Anticancer Res. 1988; 8: 985–993
  • Slater L., Sweet P., Stupecky M., Gupta S. Cyclosporin A reverses vincristine and daunorubicin resistance in acute lymphatic leukemia in vitro. J. Clin. Invest 1986; 77: 1405–1408
  • Slater L., Sweet P., Stupecky M., Wetzel M., Gupta S. Cyclosporin A corrects daunorubicin resistance in Ehrlich ascites carcinoma. Br. J. Cancer 1986; 54: 235–238
  • Mizushima Y., Kosaka H., Sakuma S., Kanda K., Itoh K., Osugi T., Mizushima A., Hamaoka T., Yoshida H., Sobue K., Fujiwara H. Cyclosporin A inhibits late steps of lymphocyte activation after transmembrane signaling. J. Biochem. 1987; 102: 1193–1201
  • Mihatsch M. J., Thiel G., Ryffel B. Morphology of cyclosporine nephropathy. Prog. Allergy 1986; 38: 447–465
  • Foxwell B. M. J., Mackie A., Ling V., Ryffel B. Identification of the multidrug resistance-related P-glycoprotein as a cyclosporine binding protein. Mol. Pharmacol. 1989; 36: 543–546

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.