6
Views
14
CrossRef citations to date
0
Altmetric
Research Article

Characterization of Muscarinic Receptor Subtypes in Canine Left Ventricular Membranes

, , , &
Pages 427-449 | Published online: 26 Sep 2008

References

  • Ashkenazi A., Winslow J. W., Peralta E. G., Peterson G. L., Schimerlik M. I., Capon D. J., Ramachandran J. An M2 muscarinic receptor subtype coupled to both adenylyl cyclase and phosphoinositide turnover. Science 1987; 238: 672–675
  • Barlow R. B., Shepherd M. K. A further search for selective antagonists at M2-muscarinic receptors. Br. J. Pharmacol. 1986; 89: 837–843
  • Bonner T. I. The molecular basis of muscarinic receptor diversity. Trends Neurosci. 1989; 12: 148–151
  • Bradford M. M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976; 72: 248–254
  • Brown J. H., Goldstein D. Analysis of cardiac muscarinic receptors recognized selectively by nonquaternary but not by quternary ligands. J. Pharmacol. Exp. Ther. 1986; 238: 580–586
  • Buckley N. J., Bonner T. I., Buckley C. M., Brann M. R. Antagonist binding properties of five cloned muscarinic receptors expressed in CHO K1 cells. Mol. Pharmacol. 1989; 35: 469–476
  • Candell L. M., Yun S. H., Ly Ly Tran P., Ehlert F. J. Differential coupling of subtypes of the muscarinic receptor to adenylate cyclase and phosphoinositide hydrolysis in the longitudinal muscle of the rat ileum. Mol. Pharmacol. 1990; 38: 689–697
  • Cheng Y.-C., Prusoff W. H. Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (IC50) of an enzymatic reaction. Biochem. Pharmacol. 1973; 22: 3099–3108
  • Clague R. V., Eglen R. M., Strachan A. C., Whiting R. L. Action of agonists and antagonists at muscarinic receptors present on ileum and atria in vitro. Br.J. Pharmacol. 1985; 86: 163–170
  • Doods H. N., Mathy M. J., Davidesko D., Van Charldorp K. J., de Jonge A., van Zwieten P. A. Selectivey of muscarinic antagonists in radioligand and in vivo experiments for the putative M1 M2 and M3 receptors. J. Pharmacol. Exp. Ther. 1987; 242: 257–262
  • Galper J. B., Dziekan L. C., O'Hara D. S., Smith T. W. The biphasic response of muscarinic cholinergic receptors an cultured heart cells to agonists. J. Biol. Chem. 1982; 257: 10344–10356
  • Giachetti A., Micheletti R., Montagna E. Cardioselective profile of AF-DX 116, a muscarinic M2 receptor antagonist. Life Sci. 1986; 38: 1663–1672
  • Giraldo E., Micheletti R., Montagna E., Giachetti A., Vigano M. A., Ladinsky H., Melchiorre C. Binding and functional characterization of the cardioselective muscarinic antagonist methoctramine. J. Pharmacol. Exp. Ther. 1988; 244: 1016–1020
  • Hammer R., Berrie C. P., Birdsall N. J. M., Burgen A. S. V., Hulme E. C. Pirenzepine distinguishs between different subclasses of muscarinic receptors. Nature 1980; 283: 90–92
  • Hammer R., Giachetti A. Muscarinic receptor subtypes: M1 and M2 biochemical and functional characterization. Life Sci. 1982; 31: 2991–2998
  • Huber F., Vulliemoz Y., Sun L. S., Robinson R. B., Bilezikian J. P. Characterization of the muscarinic receptor coupled to inositol phosphate formation in cultured myocytes from newborn rat hearts. FASEB J. 1991; 5: 2826a
  • Hulme E. C., Birdsall N. J. M., Buckley N. J. Muscarinic receptor subtypes. Annu. Rev. Pharmacol. Toxicol. 1990; 30: 633–673
  • Kubo T., Haga M. K., Ichiyama A., Kangawa K., Kojima M., Matsuo H., Hirese T., Numa S. Cloning, sequencing and expression of complementary DNA encoding the muscarinic acetylcholine receptors. Nature (Lond) 1986; 323: 411–416
  • Ladinsky H., Giraldo E., Monferini E., Schiavi G. B., Vigano M. A., de Conti L., Micheletti R., Hammer R. Muscarinic receptor heterogeneity in smooth muscle: binding and functional studies with AF-DX 116. Trends Pharmacol. Sci. 1988; 44–48, Suppl
  • Lee N. H., Ramkumar V., El-Fakahany E. E. Charge but not chemical class explains the selective binding of [3H]N-methylscopolamine to a subpopulation of [3H]quinuclidinyl benzilate binding sites in rat cerebral cortex homogenates. Eur. J. Pharmacol. 1986; 130: 153–155
  • Melchiorre C., Angeli P., Lambrecht G., Mutschler E., Picchio M. T., Wess J. Antimuscarinic actions of methoctramine, a new cardioselective M2 muscarinic receptor antagonist, alone and in combination with atropine and gallamine. Eur. J. Pharmacol. 1987; 144: 117–124
  • Micheletti R., Montagna E., Giachetti A. AF-DX 116, a cardioselective muscarinic antagonist. J. Pharmacol. Exp. Ther. 1987; 142: 628–634
  • Mutschler E., Lambrecht G. Selective muscarinic agonists and antagonists in functional tests. Trends Pharmacol. Sci. 1984; 5(Suppl I)39–44
  • Nathanson N. M. Binding of agonists and antagonists to muscarinic receptors on intact cultured heart cells. J. Neurochem. 1983; 41: 1545–1549
  • Peralta E. G., Winslow J. W., Peterson J. L., Smith D. H., Ashkennnazi A., Ramachandran J., Schimerlik M. I., Capon D. J. Primary structure and biochemical properties of an M2 receptor. Science (Wash. DC) 1987; 236: 600–605
  • Peralta E. G., Ashkenazi A., Winslow J. W., Ramachandran J., Capon D. J. Differential regulation of PI hydrolysis and adenylyl cyclase by muscarinic receptor subtypes. Nature 1988; 334: 434–437
  • Shapiro R. A., Scherer N. M., Habecker B. A., Subers E. M., Nathanson N. M. Isolation, sequence and functional expression of the mouse M1 muscarinic acetylcholine receptor gene. J. Biol. Chem. 1988; 263: 18397–18403
  • Siegel R. E., Fischbach G. D. Muscarinic receptors and responses in intact embryonic chick atrial and ventricular heart cells. Dev. Biol. 1984; 101: 346–356
  • Subers E. M., Nathanson N. M. Muscarinic acetylcholine receptor function in chick heart cells cultured in serum-free medium. J. Mol. Cell Cardiol. 1988; 20: 131–140
  • Watanabe A. M. Cardiac Therapy, M. R. Rosen, B. F. Hoffman. The Hague, Martinnus Nijhoff 1983; 95–144
  • Watanabe A. M. Cellular mechanisms of muscarinic regulation of cardiac function. Nervous Control of Cardiac Function, W. Randall. Oxford University Press, New York 1984; 130–164
  • Yang C. M., Farley J. M., Dwyer T. M. Biochemical characteristics of muscarinic cholinoreceptors in swine tracheal smooth muscle. J. Auton. Pharmacol. 1986; 6: 15–24
  • Yang C. M. Characterization of muscarinic receptors in dog tracheal smooth muscle cells. J. Autonom. Pharmacol. 1991; 11: 51–61
  • Zar J. H. Biostatistical analysis:Multiple regression and correlation. Prentice-Hall Inc., Englewood Cliffs, N. J. 1974; 252–280
  • Maeda A., Kubo T., Mishina M., Numa S. Tissue distribution of mRNAs encoding muscarinic acetylcholine receptor subtypes. FEES Lett. 1988; 239: 339–342
  • Mizushima A., Uchida S., Zhou X.-M., Kagiya T., Yoshida H. Cardiac M2 receptors consist of two different types, both regulated by GTP. Eur. J. Pharmacol. 1987; 135: 403–409
  • Lambrecht G., Feifel R., Forth B., Strohmann C., Tacke R., Mutschler E. p-Fluoro-hexahydro-sila-difenidol: the first M2b selective muscarinic antagonist. Eur. J. Pharmacol. 1988; 152: 193–194
  • Zhou X.-M., Mizushima A., Uchida S., Watanabe Y., Yoshida H. The SH-H subgroup of cardiac M2 receptor (M2a) inhibits adenylate cyclase. Eur. J. Pharmacol. 1988; 154: 229–236
  • Mizushima A., Uchida S., Zhou X.-M., Osugi T., Imaizumi T., Misaki N., Tatebayashi Y., Yoshida H. The H-L subgroup of guinea pig cardiac M2 receptors (M2B) regulates inositol phosphate formation. Eur. J. Pharmacol. 1989; 168: 375–380
  • Ford A. P. D. W., Eglen R. M., Whiting R. L. Analysis of muscarinic cholinoceptors mediating phosphoinositide hydrolysis in guinea pig cardiac muscle. Eur. J. Pharmacol. Mol. Pharmacol. Sect. 1992; 225: 105–112
  • Yang C. M., Chou S.-P., Sung T.-C. Muscarinic receptor subtypes coupled to generation of different second messengers in isolated tracheal smooth muscle cells. Br. J. Pharmacol. 1991; 104: 613–618

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.