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Research Article

Functional Testing of Human Dopamine D1 And D5 Receptors Expressed in Stable camp-Responsive Luciferase Reporter Cell Lines

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Pages 79-94 | Published online: 26 Sep 2008

References

  • Birnbaumer L., Abramowitz J., Brown A. M. Receptor-effector coupling by G proteins. Biochim. Biophys. Acta 1990; 1031: 163–224
  • Probst W. C., Snyder L., Schuster D. I., Brosius J., Sealfon S. C. Sequence alignment of the G-protein coupled receptor superfamily. DNA Cell Biol. 1992; 11: 1–20
  • Gilman A. G. G proteins: Transducers of receptor-generated signals. Annu. Rev. Biochem. 1987; 56: 615–649
  • Allen L. F., Lefkowitz R. J., Caron M. G., Cotecchia S. G-protein-coupled receptor genes as protooncogenes: Constitutively activating mutation of the α1B-adrenergic receptor enhances mitogenesis and tumorigenicity. Proc. Natl. Acad. Sci. USA 1991; 88: 11354–11358
  • Urlaub G., Chasin L. A. Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity. Proc. Natl. Acad. Sci. USA 1980; 77: 4216–4220
  • De Wet J. R., Wood K. V., DeLuca M., Helinski D. R., Subramani S. Firefly luciferase gene: structure and expression in mammalian cells. Mol. Cell. Biol. 1987; 7: 725–737
  • Montminy M. R., Gonzalez G. A., Yamamoto K. K. Regulation of cAMP-inducible genes by CREB. Trends Neurosci. 1990; 13: 184–188
  • Berkowitz L. A., Gilman M. Z. Two distinct forms of active transcription factor CREB (cAMP response element binding protein). Proc. Natl. Acad. Sci. USA 1990; 87: 5258–5262
  • Meinkoth J. L., Montminy M. R., Fink J. S., Feramisco J. R. Induction of a cyclic AMP-responsive gene in living cells requires the nuclear factor CREB. Mol. Cell. Biol. 1991; 11: 1759–1764
  • Sibley D. R., Monsma F. J. Molecular biology of dopamine receptors. Trends Pharmacol. Sci. 1992; 13: 61–69
  • Van Tol H. H. M., Bunzow J. R., Guan H. C., Sunahara R. K., Seeman P., Niznik H. B., Civelli O. Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine. Nature 1991; 350: 610–614
  • Dal Toso R., Sommer B., Ewert M., Herb A., Pritchett D. B., Bach A., Shivers B. D., Seeburg P. H. The dopamine D2 receptor: two molecular forms generated by alternative splicing. EMBO J. 1989; 8: 4025–4034
  • Sokoloff P., Giros B., Martres M. P., Bouthenet M. L., Schwartz J. C. Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics. Nature 1990; 347: 146–151
  • Giros B., Martres M. P., Pilon C., Sokoloff P., Schwartz J. C. Shorter variants of the D3 dopamine receptor produced through various patterns of alternative splicing. Biochem. Biophys. Res. Commun. 1991; 176: 1584–1592
  • Dearry A., Gingrich J. A., Falardeau P., Fremeau R. T., Bates M. D., Caron M. G. Molecular cloning and expression of the gene for a human D1 dopamine receptor. Nature 1990; 347: 72–76
  • Zhou Q. Y., Grandy D. K., Thambi L., Kushner J. A., Van Tol H. H. M., Cone R., Pribnow D., Salon J., Bunzow J. R., Civelli O. Cloning and expression of human and rat D1 dopamine receptors. Nature 1990; 347: 76–80
  • Sunahara R. K., Niznik H. B., Weiner D. M., Stormann T. M., Brann M. R., Kennedy J. L., Gelernter J. E., Rozmahel R., Yang Y., Israel Y., Seeman P., O'Dowd B. F. Human dopamine D1 receptor encoded by an intronless gene on chromosome 5. Nature 1990; 347: 80–83
  • Sunahara R. K., Guan H. C., O'Dowd B. F., Seeman P., Laurier L. G., Ng G., George S. R., Torchia J., Van Tol H. H. M., Niznik H. B. Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1. Nature 1991; 350: 614–619
  • Grandy D. K., Zhang Y., Bouvier C., Zhou Q. Y., Johnson R. A., Allen L., Buck K., Bunzow J. R., Salon J., Civelli O. Multiple human D5 dopamine receptor genes: A functional receptor and two pseudogenes. Proc. Natl. Acad. Sci. USA 1991; 88: 9175–9179
  • Weinshank R. L., Adham N., Macchi M., Olsen M. A., Branchek T. A., Hartig P. R. Molecular cloning and characterization of a high affinity dopamine receptor (D1β) and its pseudogene. J. Biol. Chem. 1991; 266: 22427–22435
  • Short J. M., Fernandez J. M., Sorge J. A., Huse W. D. Lambda ZAP: a bacteriophage lambda expression vector with in vivo excision properties. Nucleic Acids Res. 1988; 16: 7583–7600
  • Saiki R. K., Gelfand D. H., Stoffel S., Scharf S. J., Higuchi R., Horn G. T., Mullis K. B., Ehrlich H. A. Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science 1988; 239: 487–491
  • Voraberger G., Schäfer R., Stratowa C. Cloning of the human gene for intercellular adhesion molecule 1 and analysis of its 5′-regulatory region: Induction by cytokines and phorbol ester. J. Immunol. 1991; 147: 2777–2786
  • Schatt M. D., Rusconi S., Schaffner W. A single DNA-binding transcription factor is sufficient for activation from a distant enhancer and/or from a promoter position. EMBO J. 1990; 9: 481–487
  • McKnight S. L. The nucleotide sequence and transcript map of the herpes simplex virus thymidine kinase gene. Nucleic Acids Res. 1980; 8: 5949–5964
  • Himmler A., Maurer-Fogy I., Krönke M., Scheurich P., Pfizenmaier K., Lantz M., Olsson I., Hauptmann R., Stratowa C., Adolf G. R. Molecular cloning and expression of human and rat tumor necrosis factor receptor chain (p60) and its soluble derivative, tumor necrosis factor-binding protein. DNA Cell Biol. 1990; 9: 705–715
  • Brasier A. R., Tate J. E., Habener J. F. Optimized use of the firefly luciferase assay as a reporter gene in mammalian cell lines. BioTechniques 1989; 7: 1116–1121
  • Montmayeur J. P., Borrelli E. Transcription mediated by a cAMP-responsive promoter element is reduced upon activation of dopamine D2 receptors. Proc. Natl. Acad. Sci. USA 1991; 88: 3135–3139

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