8
Views
8
CrossRef citations to date
0
Altmetric
Research Article

Biochemical Characterization and Solubilization of Human NK2 Receptor Expressed in Chinese Hamster Ovary Cells

, &
Pages 639-652 | Published online: 26 Sep 2008

References

  • Maggio J. E. Tachykinins. Ann. Rev. Neurosci. 1988; 11: 13–28
  • Nakanishi S. Mammalian tachykinin receptors. Ann. Rev. Neurosci. 1991; 14: 123–136
  • McElroy B. A., Clegg S. P., Deal M. J., Ewan G. B., Hagan R. M., Lreland S. J., Jordan C. C., Porter B., Ross B. C., Ward P., Whittington A. R. Highly potent and selective heptapeptide antagonists of the neurokinin NK2 receptor. J. Med. Chem.
  • Maggi C. A., Patacchini R., Giuliani S., Rovero P., Dion S., Regoli D., Giachetti A., Meli A. Competitive antagonists discriminate between NK2 tachykinin receptor subtypes. Br. J. Pharmacol. 1990; 100: 588–592
  • Arkinstall S., Chollet A. I., Ceszkowski K., Losberger C., Gillieron C., Chollet A., Kawashima E. Biochemical characterization of a functional human NK2 receptor; evidence for multiple signal trans-duction pathways regulated by PKC, In preparation
  • Ceszkowski K., Chollet A. Synthesis of fluoresceinyl neurokinin-A, a biologically active probe for NK2 receptors. BioMed. Chem. Lett. 1992, in press
  • Laemmli U. K. Cleavage of structural proteins during the assembly of the head bacteriophage T4. Nature 1970; 227: 680–685
  • Lowry O. H., Rosebrough N. J., Farr A. L., Randall R. J. Protein measurements with the Folin phenol reagent. J. Biol. Chem. 1951; 193: 265–275
  • Bruns R. F., Lawson-Wendling K., Pugsley T. A. A rapid filtration assay for soluble receptors using polyethylenimine-treated filters. Anal. Biochem. 1983; 132: 74–81
  • Munson P. J., Roadbard D. LIGAND: a versatile computerisedapproach for the characterisation of ligand binding studies. Anal. Biochem. 1980; 107: 229–239
  • McPherson G. A. Analysis of radioligand experiments: A collection of computer programs for the IBM PC. J. Pharmacol. Methods 1985; 14: 213–228
  • Wurm F. M. Integration, amplification and stability of plasmid sequences in CHO cell cultures. Biologicals 1990; 18: 159–164
  • Hagan R. M., Ireland S. J., Jordan C. C., Beresford I. J. M., Deal M. J., Ward P. Receptor-selective, peptidase-resistant agonists at neurokinin NK-1 and NK-2 receptors: new tools for investigating neurokinin function. Neuropeptides 1991; 19: 127–135
  • Savarese T. M., Fraser C. M. In vitro mutagenesis and the search for structure-function relationships among G protein-coupled receptors. Biochem. J. 1992; 283: 1–19
  • Grandordy B. M., Frossard N., Rhoden K. J., Barnes P. J. Tachykinin-induced phosphoinositide breakdown in airway smooth muscle and epithelium: relationship to contraction. Molec. Pharmacol. 1988; 33: 515–519
  • Chen Y., Couvineau A., Laburthe M., Amiranoff B. Solubilization and molecular characterization of active galanin receptors from rat brain. Biochemistry 1992; 31: 2415–2422
  • Nakata Y., Tanaka H., Morishima Y., Segawa T. Solubilization and characterization of substance P binding protein from bovine brainstem. J. Neurochem. 1988; 50: 522–527
  • Murata M., Eto Y., Shibai H. Large-scale production of erythroid differentiation factor by gene engineered CHO cells in suspension culture. J. Ferment. Technol. 1988; 66: 501–507
  • Kurtenbach E., Curtis C. A. M., Pedder E. K., Aitken A., Harris A. C. M., Hulme E. C. Muscarinic acetylcholine receptors: peptide sequencing identifies residues involved in antagonist binding and disulfide bond formation. J. Biol. Chem. 1990; 265: 13702–13708

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.