23
Views
1
CrossRef citations to date
0
Altmetric
Original Article

Minireview: Genetic Manipulations of Cholinergic Communication Reveal Trans-Acting Control Mechanisms Over Acetylcholine Receptors

, , , &
Pages 279-291 | Published online: 26 Jun 2009

References

  • Gadbut A. P., Galper J. B. A novel M3 muscarinic acetylcholine receptor is expressed in chick atrium and ventricle. J. Biol. Chem. 1994; 269: 25823–25829
  • Elgoyhen A. B., Johnson D. S., Boulter J., Vetter D. E., Heinemann S. α9: an acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells. Cell 1994; 79: 705–715
  • Durr I., Numberger M., Berberich C., Witzemann V. Characterization of the functional role of E-box elemements for the transcriptional activity of rat acetylcholine receptor E-subunit and δ-subunit gene promoters in primary muscle cell cultures. Eur. J. Biochem. 1994; 224: 353–364
  • Yang X., McDonough J., Fyodorov D., Morris M., Wang F., Deneris E. S. Characterization of an acetylcholine receptor α 3 gene promoter and its activation by the POU domain factor SCIP/Tst-1. J. Biol. Chem. 1994; 269: 10252–10264
  • Yu X. M., Hall Z. W. A sequence in the main cytoplasmic loop of the α subunit is required for assembly of mouse muscle nicotinic acetylcholine receptor. Neuron 1994; 13: 247–255
  • Van-Koppen C. J., Sell A., Lenz W., Jakobs K. H. Deletion analysis of the m4 muscarinic acetylcholine receptor. Molecular determinants for activation of but not coupling to the Gi guanine-nucleotide-binding regulatory protein regulate receptor internalization. Eur. J. Biochem. 1994; 222: 525–531
  • Sepish D. S., Ho R. K., Westerfield M. Autonomous expression of the nicl acetylcholine receptor mutation in zebrafish muscle cells. Dev. Biol. 1994; 161: 84–90
  • Treinin M., Chalfie M. A mutated acetylcholine receptor subunit causes neuronal degeneration in C elegans. Neuron 1995; 14: 871–877
  • Gomez C. M., Gammack J. T. A leucine-to-phenylalanine substitution in the acetylcholine receptor ion channel in a family with the slow-channel syndrome. Neurology 1995; 45: 982–985
  • Ohno K., Hutchinson D. O., Milone M., Brengman J. M., Bouzat C., Sine S. M., Engel A. G. Congenital myasthenic syndrome caused by prolonged acetylcholine receptor channel openings due to a muttion in the M2 domain of the E subunit. Proc. Natl. Acad. Sci. USA 1995; 92: 758–762
  • Kreienkamp H. J., Sine S. M., Maeda R. K., Taylor P. Glycosylation sites selectively interfere with α-toxin binding to the nicotinic acetylcholine receptor. J. Biol. Chem. 1994; 269: 8108–8114
  • Hoffman P. W., Ravindran A., Huganir R. L. Role of phosphorylation in desensitization of acetylcholine receptors expressed in Xenopus oocytes. J. Neurosci. 1994; 14: 4185–4195
  • Tang J., Jo S. A., Burden S. J. Separate pathways for synapse-specific and electrical activity-dependent gene expression in skeletal muscle. Development 1994; 120: 1799–1804
  • Shapira M., Seidman S., Sternfeld M., Timberg R., Kaufer D., Patrick J., Soreq H. Transgenic engineering of neuromuscular junctions in Xenopus laevis embryos transiently overexpressing key cholinergic proteins. Proc. Natl. Acad. Sci. USA 1994; 91: 9072–9076
  • Seidman S., Sternfeld M., Ben Aziz-Aloya R., Timberg R., Kaufer D., Soreq H. Synaptic versus epidermal accumulation of human acetylcholinesterase is encoded by alternative 3'-terminal exons. Mol. Cell Biol. 1995; 14: 459–473
  • Andres C., Beeri R., Friedman A., Timberg R., Shani M., Soreq H. Transgenic ACHE induces neuromuscular deterioration in mice, Submitted for publication
  • Beeri R., Andres C., Lev-Lehman E., Timberg R., Huberman T., Shani M., Soreq H. Transgenic expression of human acetylcholinesterase induces progressive deterioration in mice. Curr. Biol. 1995; 9: 1063–1071
  • Broide R. S., O'Connor L. T., Smith M. A., Smith J. A. M., Leslie F. M. Developmental expression of α7 neuronal nicotinic receptor messenger RNA in rat sensory cortex and thalamus. Neuroscience 1995; 67: 83–94
  • Gunderson K., Sanes J. R., Merlie J. P. Neural regulation of muscle acetylcholine receptor - and α-subunit gene promoters in transgenic mice. J. Cell Biol. 1993; 123: 1535–1544
  • Chu G. C., Moscoso L. M., Sliewkowski M. X., Merlie J. P. Regulation of the acetylcholine receptor subunit gene by recombinant ARIA: an in vitro model for transynaptic gene regulation. Neuron. 1995; 2: 329–339
  • Daubas P., Salmon A. M., Zoli M., Geoffroy B., Devillers-Thiery A., Bessis A., Medevielle F., Changeux J. P. Chicken neuronal acetylcholine receptor α 2-subunit gene exhibits neuron-specific expression in the brain and spinal cord of transgenic mice. Proc. Natl. Acad. Sci. USA 1993; 90: 2237–2241
  • Picciotto M. R., Zoli M., Lena C., Bessis A., Lallemand Y., LeNovere N., Vincent P., Merlo Pich E., Brulet P., Changeux J. P. Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain. Nature 1995; 374: 65–67
  • Grifman M., Lev-Lehman E., Ginzberg D., Eckstein F., Zakut H., Soreq H. Potential antisense oligonucleotide therapies for neurodegenerative diseases. Concepts in Gene Therapy, M. Strauss, J. A. Barranger. Walter de Gruyter, Berlin 1996, in press
  • Luetje C. W., Piattoni M., Patrick J. W. Mapping of ligand binding sites of neuronal nicotinic acetylcholine receptors using chimeric α subunits. Mol. Pharmacol. 1993; 44: 657–666
  • Brussard A. B., Yang X., Doyle J. P., Huck S., Role L. W. Developmental regulation of multiple nicotinic AChR channel subtypes in embryonic chick habenula neurons: contributions of both the alpha 2 and alpha 4 subunit genes. Pflugers-Arch.-Eur. J. Physiol. 1995; 429: 27–43
  • Huang X. Y., Morielli A. D., Peralta E. G. Tyrosine kinase-dependent suppression of a potassium channel by the G protein-coupled ml muscarinic acetylcholine receptor. Cell 1993; 75: 1136–1145
  • Karpel R., Sternfeld M., Ginzberg D., Guhl E., Graessman A., Soreq H. Overexpression of alternative human acetylcholinesterase forms modulates process extensions in cultured glioma cells. J. Neurochem. 1996; 66: 114–123

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.