17
Views
5
CrossRef citations to date
0
Altmetric
Original Article

The Uncoupled State of the Human Formyl Peptide Receptor

, &
Pages 327-340 | Published online: 10 Jul 2009

References

  • Ainsworth T. M., Lynam E. B., Sklar L. A. Neutrophil Function in Inflammation and Infection. Cellular and Molecular Pathogenesis, A. E. Sirica. Lippincott-Raven Publishers, Philadelphia 1996; 37–55
  • De Lean A., Stadel J. M., Lefkowitz R. J. A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled β-adrenergic receptor. J. Biol. Chem. 1980; 255: 7108–7117
  • Samama P., Cotecchia S., Costa T., Lefkowitz R. J. A mutation-induced activated state of the β2-adrenergic receptor. Extending the ternary complex model. J. Biol. Chem. 1993; 268: 4625–4636
  • Sklar L. A., Fay S. P., Seligmann B. E., Freer R. J., Muthukumaraswamy N., Mueller H., Omann G. M., Porasik M. M., Omann G., Oacles Z. Fluorescence analysis of the size of a binding pocket of a peptide receptor at natural abundance. Biochemistry 1990; 29: 313–316
  • Fay S. P., Domalewski M. D., Sklar L. A. Evidence for protonation in the human neutrophil formyl peptide receptor binding pocket. Biochemistry 1993; 32: 1627–1631
  • Fay S. P., Posner R. G., Swann W. N., Sklar L. A. Real-time analysis of the assembly of ligand, receptor, and G protein by quantitative fluorescence flow cytometry. Biochemistry 1991; 30: 5066–5075
  • Sklar L. A., Bokoch G. M., Button D., Smolen J. E. Regulation of ligand-receptor dynamics by guanine nucleotides: real time analysis of interconverting states for the neutrophil formyl peptide receptor. J. Biol. Chem. 1987; 262: 135–139
  • Sklar L. A., Mueller H., Omann G., Oades Z. Three states for the formyl peptide receptor on intact cells. J. Biol. Chem. 1989; 264: 8483–8486
  • Prossnitz E. R., Schreiber R. E., Bokoch G. M., Ye R. D. Binding of low affinity N-formyl peptide receptors to G protein. Characterization of a novel inactive receptor intermediate. J. Biol. Chem. 1995; 270: 10686–10694
  • Ferrante A., Thong Y. H. Optimal conditions for simultaneous isolation of mononuclear and polymorphonuclear leukocytes from human peripheral blood by the ficoll-hypaque method. J. Immunol.Methods 1980; 36: 109–117
  • Prossnitz E. R., Quehenberger O., Cochrane C. G., Ye R. D. The role of the third intracellular loop of the neutrophil N-formyl peptide receptor in G protein coupling. Biochem. J. 1993; 294: 581–587
  • Neubig R. R., Sklar L. A. Subsecond modulation of formyl peptide-linked guanine nucleotide-binding proteins by guanosine 5'-o-(3-thio)triphosphate in permeabilized neutrophils. Mol Pharm 1993; 43: 734–740
  • Hoffman J. F., Keil M. L., Riccobene T. A., Omann G. M., Linderman J. J. Interconverting receptor states at 4 degrees C for the neutrophil N- formyl peptide receptor. Biochemistry 1996; 35: 13047–13055
  • Domalewski M. D., Guyer D. A., Freer R. J., Muthukumaraswamy N., Sklar L. A. Fixation traps formyl peptide receptors in high and low affinity forms that can be regulated by GTP[S] in the absence of ligand. J. Recept Signal Transduct Res 1996; 16: 59–75
  • Sklar L. A., Finney D. A., Oades Z. G., Jesaitis A. J., Painter R. G., Cochrane C. G. The dynamics of ligand-receptor interactions. Real-time analyses of association, dissociation, and internalization of an N-formyl peptide and its receptors on the human neutrophil. J. Biol. Chem 1984; 259: 5661–5669
  • Sklar L. A., Hyslop P. A., Oades Z. G., Omann G. M., Jesaitis A. J., Painter R. G., Cochrane C. G. Signal transduction and ligand-receptor dynamics in the human neutrophil. Transient responses and occupancy-response relations at the formyl peptide receptor. J. Biol. Chem 1985; 260: 11461–11467

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.