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Original Article

Benzophenone-Type Photoactivatable Derivatives of α-Neurotoxins and α-Conotoxins in Studies on Torpedo Nicotinic Acetylcholine Receptor

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Pages 559-571 | Published online: 10 Jul 2009

References

  • Kreienkamp H.-J., Utkin Yu., Weise C., Machold J., Tsetlin V., Hucho F. Investigation of ligand-binding sites of the acetylcholine receptor using photoactivatable derivatives of neurotoxin II from Naja naja oxiana. Biochemistry 1992; 31: 8239–8244
  • Machold J., Weise C., Utkin Yu., Franke P., Tsetlin V., Hucho F. A new class of photoactivatable and cleavable derivatives of neurotoxin II from Naja naja oxiana. Synthesis, characterisation and application for affinity labelling of the niconic acetylcholine receptor from Torpedo californica. Eur. J. Biochem. 1995; 228: 947–954
  • Utkin Yu., Hatanaka Ya., Franke P., Machold J., Hucho F., Tsetlin V. Synthesis of nitrodiazirinyl derivatives of neurotoxin II from Naja naja oxiana and their interaction with the Torpedo californica nicotinic acetylcholine receptor. J. Protein Chem. 1995; 14: 197–203
  • Brunner J. New photolabeling and crosslinking methods. Annu. Rev. Biochem. 1993; 62: 483–514
  • Machold J., Utkin Yu., Kirsch D., Kaufmann R., Tsetlin V., Hucho F. Photolabeling reveals the proximity of the α-neurotoxin binding site to M2 helix of the ion channel in the nicotinic acetylcholine receptor. Proc. Natl. Acad. Sci. USA 1995; 92: 7282–7286
  • Dorman G., Prestwich G. Benzophenone photophores in biochemistry. Biochemistry 1994; 33: 5661–5673
  • Parker J. M. R., Hodges R. S., II. Photoaffinity probes provide a general method to prepare peptide-conjugates from native protein fragments. J. Protein Chem. 1985; 3: 479–489
  • Tsetlin V. I., Karlsson E., Utkin Yu. N., Pluzhnikov K. A., Arseniev A. S., Surin A. M., Kondakov V. I., Bystrov V. F., Ivanov V. T., Ovchinnikov Yu. A. Interacting surfaces of neurotoxins and acetylcholine receptor. Toxicon 1982; 20: 83–93
  • Lobel P., Kao P., Birken A., Karlin A. Binding of a curarimimetic toxin from cobra venom to the nicotinic acetylcholine receptor. Interactions of six biotinyltoxin derivatives with receptor and avidin. J. Biol. Chem. 1985; 260: 10605–10612
  • Utkin Yu., Krivoshein A., Davydov V., Kasheverov I., Franke P., Maslennikov I., Arseniev A., Hucho F., Tsetlin V. Labeling of T. californica nicotinic acetylcholine receptor subunits by cobratoxin derivatives with photoactivatable groups of different chemical nature at Lys23. Eur. J. Biochem. 1998; 253: 229–235
  • Hashimoto K., Uchida S., Yoshida H., Nishiuchi Y., Sakakibara S., Yukari K. Structure-activity relations of conotoxins at the neuromuscular junction. Eur. J. Pharmacol. 1985; 118: 351–354
  • Utkin Yu. N., Kobayashi Y., Hucho F., Tsetlin V. I. Relationship between the binding sites for an α-conotoxin and snake venom neurotoxins in the nicotinic acetylcholine receptor from Torpedo californica. Toxicon 1994; 32: 1153–1157
  • Hann R., Pagan O., Eterovic V. The α-conotoxins G1 and M1 distinguish between the nicotinic acetylcholine receptor agonist sites while SI does not. Biochemistry 1994; 33: 14058–14063
  • Guddat L., Martin J., Shan L., Edmundson A., Gray W. Three-dimensional structure of the α-conotoxin G1 at 1.2A resolution. Biochemistry 1996; 35: 11329–11335
  • Maslennikov I., Sobol A., Gladky K., Lugovskoy A., Ostrovsky A., Tsetlin V., Ivanov V., Arseniev A. Two distinct structures of α-conotoxin G1 in aqueous solution. Eur. J. Biochem. 1998; 254: 238–247
  • Sine S., Kreienkamp H.-J., Bren N., Maeda R., Taylor P. Molecular dissection of subunit interfaces in the acetylcholine receptor: identification of determinants of alpha-conotoxin M1 selectivity. Neuron 1995; 15: 205–211
  • Mayers R., Zafaralla G., Gray W., Abbott J., Cruz L., Olivera B. α-Conotoxins, small peptide probes of nicotinic acetylcholine receptors. Biochemistry 1991; 30: 9370–9377

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