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Research Article

An active film-coating approach to enhance chemical stability of a potent drug molecule

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Pages 227-235 | Received 29 Jul 2010, Accepted 02 Oct 2010, Published online: 12 Nov 2010

References

  • Badawy SIF, Badawy S, Williams RC, Gilbert DL. Effect of different acids on solid state stability of an ester prodrug of IIb/IIa antagonist. Pharm Dev Technol 1999;4:325–331.
  • Badawy SIF, Williams RC, Gilbert D. Chemical stability of an ester prodrug of a IIb/IIIa antagonist in solid dosage forms. J Pharm Sci 1999;8:428–433.
  • Badawy S, Vickery R, Shah K, Hussain M. Effect of processing and formulation variables on the stability of a salt of a weakly basic drug candidate. Pharm Dev Tech 2005;9:239–245.
  • Tabata T, Makino T, Kashihara T, Hirari S, Kitamori N, Toguchi H. Stabilization of new antiulcer drug (lansoprazole) in the solid dosage forms. Drug Dev Ind Pharm 1992;18:1437–1447.
  • Zannou EA, Ji Q, Joshi YM, Serajuddin ATM. Stabilization of the maleate salt of a basic drug by adjustment of microenvironmental pH in solid dosage form. Int J Pharm 2007;337:210–218.
  • Mwesigwa E, Basit AW, Buckton G. Moisture sorption and permeability characteristics of polymer films: Implications for their use as barrier coatings for solid dosage forms containing hydrolyzable drug substances. J Pharm Sci 2008;97:4433–4445.
  • Kallion RB, Stella VJ. The nucleophilicity of dextrose, sucrose, sorbitol and mannitol with p-nitrophenylesters in aqueous solution. Int J Pharm 1990;66:149–155.
  • Serajuddin A, Thakur A, Ghoshal R, Fakes M, Ranadive S, Morris K, Varia S. Selection of solid dosage form composition through drug-excipient compatibility testing. J Pharm Sci 1999;7:696–704.
  • Gu L, Strickley RG, Chi LH, Chowhan ZT. Drug-excipient incompatibility studies of the dipeptide angiotensin-converting enzyme inhibitor, moexipril hydrochloride: Dry powder vs. wet granulation. Pharm Res 1990;7:379–383.
  • Chen W, Chang S, Kiang S, Marchut A, Lynberg O, Wang J, Rao V, Desai D, Stamato H, Early W. Modeling of pan coating process: Prediction of tablet content uniformity and determination of critical process parameters. J Pharm Sci 2010;99:3213–3224.
  • Chen W, Chang S, Kiang S, Early W, Paruchuri S, Desai D. The measurement of spray quality for pan coating processes. J Pharmaceut Innov 2008;3:1872–1875.
  • El Hagrasy A, Chang S-Y, Desai D, Kiang S. Application of Raman spectroscopy for quantitative in-line monitoring of tablet coating. Am Pharmaceut Rev 2006;9(1):404–5
  • El Hagrasy A, Chang S-Y, Desai D, Kiang S. Raman spectroscopy for the determination of coating uniformity of tablets: Assessment of product quality and coating pan mixing efficiency during scale-up. J Pharmaceut Innov 2006, 1:137–42.
  • Fichana D, Marchut A, Ohlsson P, Chang S, Lyngberg O, Dougherty J, Kiang S, Stamato H, Chaudhuri B, Muzzio F. Experimental and model-based approaches to studying mixing in coating pans. Pharmaceut Develop Technol 2009;14(2):1731–84.
  • Lipper R, Desai D, Kiang S. Case study: Implementation of design space concepts in development of an active-coated tablet. Real world applications of PAT and QbD in drug process development and approval. September 11, 2006, Arlington, VA.
  • Kwan H, Liebowitz S. Stable extended release oral dosage composition comprising loratidine and pseudoephedrine. US patent 5,314,697; May 24, 1994.
  • Bova J, Dunne J. (Monitoring only) Combinations of HMG-COA reductase inhibitors and nicotinic acid compounds and methods for treating hyperlipidemia once a night. Pub. no. US2009/0226518A1; publication date September 10, 2009.

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