266
Views
16
CrossRef citations to date
0
Altmetric
Research Article

A pH/enzyme-responsive polymer film consisting of Eudragit® FS 30 D and arabinoxylane as a potential material formulation for colon-specific drug delivery system

, , , &
Pages 429-436 | Received 10 Sep 2010, Accepted 22 Nov 2010, Published online: 11 Jan 2011

References

  • Souto-Maior JFA, Reis AV, Pedreiro LM, Cavalcanti OA. Phosphated crosslinked pectin as a potential excipient for specific drug delivery: preparation and physicochemical characterization. Polym Int 2010;59:127–135.
  • Reddy SM, Sinha VR, Reddy DS. Novel oral colon-specific drug delivery systems for pharmacotherapy of peptide and nonpeptide drugs. Drugs Today 1999;35:537–580.
  • Sinha VR, Kumria R. Microbially triggered drug delivery to the colon. Eur J Pharm Sci 2008;18:3–18.
  • Friend DR. New Oral delivery systems for treatment of inflammatory bowel disease. Adv Drug Deliv Rev 2005;57:247–265.
  • Rubistein A. Colonic drug delivery. Drug Discov Today 2005;2:33–37.
  • Freire AC, Podczeck F, Sousa J, Veiga, F. Liberação específica de fármacos no cólon por via oral. I− O cólon como local de liberação de fármacos. Rev Bras Cienc Farm 2006a; 42:319–335.
  • Freire AC., Podczeck F, Sousa J, Veiga F. Liberação específica de fármacos no cólon por via oral. II - Tipos de sistemas utilizados. Rev Bras Cienc Farm 2006b; 42:337–355.
  • Sinha VR, Mittal BR, Bhutani KK, Kumria R. Colonic drug delivery of 5-fluorouracil: an in vitro evaluation. Int J Pharm 2004;269:101–108.
  • Jain A, Gupta Y, Jain SK. Perspectives of Biodegradable Natural Polysaccharides for Site-Specific Drug Delivery to the Colon. J Pharm Pharm Sci 2008;10:86–128.
  • Pinto, JF. Site-specific drug delivery systems within the gastro-intestinal tract: from the mouth to the colon. Int J Pharm 2010;395:44–52.
  • Chourasia MK, Jain SK. Pharmaceutical aproaches to colon targeted drug delivery systems. J Pharm Pharm Sci 2003;6:33–66.
  • McConnell EL, Short MD, Basi AW. An in vivo comparison of intestinal pH and bacteria as physiological trigger mechanisms for colonic targeting in man. J Control Release 2008;130:154–160.
  • Sinha VR, Kumria R. Polysaccharides in colon-specific drug delivery. Int J Pharm 2001;224:19–38.
  • Yang L, Chu JS, Fix JA. Colon-specific drug delivery: new approaches and in vitro/in vivo evaluation. Int J Pharm 2002;235:1–15.
  • Akhgari A, Farahmand F, Garekania HA, Sadeghia F, Vandamme TF. Permeability and swelling studies on free films containing inulin in combination with different polymethacrylates aimed for colonic drug delivery. Eur J Pharm Sci 2006;28:307–314.
  • Wei H, Li-Fang F, Bai X, Chun-Lei L, Qing, D. Yong-Zhen C, De-Ying C. An investigation into the characteristics of chitosan/Kollicoat SR30D free films for colonic drug delivery. Eur J Pharm Sci 2009;72:266–274.
  • Grootaert C, Delcour JA, Courtinb, CM, Broekaertb WF, Verstraetea W, Wiele, TV. Microbial metabolism and prebiotic potency of arabinoxylan oligosaccharides in the human intestine. Trends food sci technol 2007;18:64–71.
  • Vandamme TF, Lenourry A, Charrueau C, Chaumeil JC. The use of polysaccharides to target drugs to the colon. Carbohyd Polym 2002;48:219–231.
  • Van Craeyveld V, Delcour JA, Courtin CM. Extractability and chemical and enzymic degradation of psyllium (Plantago ovata Forsk) seed husk arabinoxylans. Food Chem 2009;111:812–819.
  • Saghir S, Iqbal MS, Hussain MA, Koschella A, Heinze T. Structure characterization and carboxymethylation of arabinoxylan isolated from Ispaghula (Plantago ovata) seed husk. Carbohyd Polym 2008;74:309–317.
  • Singh B. Psyllium as therapeutic and drug delivery agent. Int J Pharm 2007;334:1–14.
  • Kaith BS, Kumar K. In vacuum synthesis of psyllium and acrylic acid based hydrogels for selective water absorption from different oil–water emulsions. Desalination 2008;229:331–341.
  • Evonik Industries. Eudragit® FS 30 D A versatile polymer for controlled release aplications. Available at: <http://www.pharma-polymere.de/pharmapolymers/en/eudragitfs30d/>. Access: 3 March 2009.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.