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Research Article

Deposition of non-spherical particles in bifurcating airways

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Pages 942-951 | Received 11 Aug 2013, Accepted 19 Aug 2013, Published online: 10 Dec 2013

References

  • Marianecci C, Di Marzio L, Rinaldi F, et al. Pulmonary delivery: innovative approaches and perspectives. J Biomater Nanobiotech 2011;2:567–575
  • Sanders M. Pulmonary drug delivery: an historical overview. In: Smyth HDC, Hickey AJ, eds. Controlled pulmonary drug delivery. New York: Springer New York; 2011:51–73
  • Pavia D, Thomson ML, Clarke SW, Shannon HS. Effect of lung function and mode of inhalation on penetration of aerosol into the human lung. Thorax 1977;32:194–197
  • Schlesinger RB, Bohning DE, Chan TL, Lippmann M. Particle deposition in a hollow cast of the human tracheobronchial tree. J Aerosol Sci 1977;8:429–445
  • Emmett PC, Aitken RJ, Hannan WJ. Measurements of the total and regional deposition of inhaled particles in the human respiratory tract. J Aerosol Sci 1982;13:549–560
  • Kim CS, Fisher DM. Deposition characteristic of aerosol particles in sequentially bifurcating airway models. Aerosol Sci Technol 1999;31:198–220
  • Oldham AJ, Phalen RF, Heistracher T. Computational fluid dynamic prediction and experimental results for particle deposition in an airway model. Aerosol Sci Technol 2000;32:61–71
  • Zhou Y, Chen YS. Particle deposition in a cast of human tracheobronchial airways. Aerosol Sci Technol 2005;39:492–500
  • Zhang Z, Kleinstreuer C. Effect of particle inlet distributions on deposition in a triple bifurcating airway model. J Aerosol Med 2001;14:13–29
  • Longest PW, Vinchurkar S, Martonen T. Transport and deposition of respiratory aerosols in model of childhood asthma. J Aerosol Sci 2006;37:1234–1257
  • Farkas A, Balashazy I. Simulation of the effect of local obstructions and blockage on airflow and aerosol deposition in central human airways. J Aerosol Sci 2007;38:865–884
  • Kaialy W, Alahalaweh A, Velaga S, Nokhodchi A. Effect of carrier particle shape on dry powder inhaler performance. Int J Pharm 2011;421:12–23
  • Zeng XM, Martin GP, Marriott C, Pritchard J. The influence of carrier morphology on drug delivery by dry powder inhalers. Int J Pharm 2000;200:93–106
  • Champion JA, Katare YK, Mitragotri S. Particle shape: a new design parameter for micro- and nanoscale drug delivery carriers. J Control Release 2007;121:3–9
  • Geng Y, Dalhaimer P, Cai S, et al. Shape effects of filaments versus spherical particles in flow and drug delivery. Nat Nanotechnol 2007;2:249–255
  • Hu TT, Zhao H, Jiang LC, et al. Engineering pharmaceutical fine particles of budesonide for dry powder inhalation (DPI). Ind Eng Chem Res 2008;48:9623–9327
  • Hassan MS, Lau RWM. Effect of paricle shape on dry particle inhalation: study of flowability, aerosolization, and deposition properties. AAPS PharmSciTech 2009;10:1252–1262
  • Edwards DA, Hanes J, Caponetti G, et al. Large porous particles for pulmonary drug delivery. Science 1997;276:1868–1871
  • Hirst PH, Pitcairn GR, Weers JG, et al. In vivo lung deposition of hollow porous particles from pressurized metered dose inhaler. Pharm Res 2002;19:258–264
  • Su WC, Cheng YS. Deposition of manmade fibers in human respiratory airway casts. J Aerosol Sci 2009;40:270–284
  • Rhodes M, ed. Introduction to particle technology. 2nd ed. New Jersey: John Wiley & Sons Hoboken; 2008
  • Gawronski R, Szewczyk KW. Inertial deposition of particles in the human branching airways. J Aerosol Sci 1985;17:795–801
  • Chan TL, Schreck RM. Effect of the laryngeal jet on particle deposition in the human trachea and upper bronchial airways. J Aerosol Sci 1980;11:447–459
  • Davies CN. Diffusion and sedimentation of aerosol particle from poiseuille flow in pipes. J Aerosol Sci 1973;4:317–328
  • Weibel ER. Morphometry of the human lung. Berlin: Springer; 1963
  • Howatson Tawhai M, Pullan AJ, Hunter PJ. Generation of an anatomically based three-dimensional model of conducting airways. Ann Biomed Eng 2000;28:793–802

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