247
Views
8
CrossRef citations to date
0
Altmetric
Research Article

Long-term controlled release of PLGA microparticles containing antidepressant mirtazapine

, , , , &
Pages 214-221 | Received 25 Mar 2014, Accepted 18 Nov 2014, Published online: 11 Dec 2014

References

  • Ito F, Fujimori H, Makino K. Incorporation of water-soluble drugs in PLGA microspheres. Colloids Surf B 2007;54:173–178
  • Gabor F. Ketoprofen-poly (d, l-lactic-co-glycolic acid) microspheres: influence of manufacturing parameters and type of polymer on the release characteristics. J Microencapsul 1999;16:1–12
  • Mehta RC, Jeyanthi R, Thanoo BC, et al. Biodegradable microspheres as depot system for patenteral delivery of peptide drugs. J Control Release 29;1994:375–384
  • Vasir JK, Tambwekar K, Garg S. Bioadhesive microspheres as a controlled drug delivery system. Int J Pharm 2003;255:13–32
  • Gavini E, Chetoni P, Cossu M, et al. PLGA microspheres for the ocular delivery of a peptide drug, vancomycin using emulsification/spray-drying as the preparation method: in vitro/in vivo studies. Eur J Pharm Biopharm 2004;57:207–212
  • Gelperina S, Kisich K, Iseman MD, Heifets L. The potential advantages of nanoparticle drug delivery systems in chemotherapy of tuberculosis. Am J Respir Crit Care 2005;172:1487–1490
  • Kim SJ, Hahn SK, Kim MJ, et al. Development of a novel sustained release formulation of recombinant human growth hormone using sodium hyaluronate microparticles. J Control Release 2005;104:323–335
  • Agnihotri SA, Aminabhavi TM. Formulation and evaluation of novel tableted chitosan microparticles for the controlled release of clozapine. J Microencapsul 2004;21:709–718
  • Devoto P, Flore G, Pira L, et al. Mirtazapine-induced corelease of dopamine and noradrenaline from noradrenergic neurons in the medial prefrontal and occipital cortex. Eur J Pharmacol 2004;487:105–111
  • Montgomery SA. Safety of mirtazapine: a review. Int Clin Psychopharmacol 1995;10:37–45
  • Roosea SP. Compliance: the impact of adverse events and tolerability on the physician’s treatment decisions. Eur Neuropsychopharmacol 2003;13:85–92
  • Li M, Rouaud O, Poncelet D. Microencapsulation by solvent evaporation: state of the art for process engineering approaches. Int J Pharm 2008;363:26–39
  • Beck LR, Cowsar DR, Lewis DH. A new long-acting injectable microcapsule system for the administration of progesterone. Fertil Steril 1979;31:545–551
  • Pistner H, Gutwald R, Ordung R, et al. Poly (l–lactide): a long-term degradation study in vivo: I. Biological results. Biomaterials 1993;14:671–677
  • Kajjari PB, Manjeshwar LS, Aminabhavi TM. Novel blend microspheres of poly (3-hydroxybutyrate) and Pluronic F68/127 for controlled release of 6-mercaptopurine. J Appl Polym Sci 2014;131:40196, doi: 10.1002/app.40196
  • Agbay A, Mohtaram NK, Willerth SM. Controlled release of glial cell line-derived neurotrophic factor from poly (ε-caprolactone) microspheres. Drug Deliv Transl Res 2014;4:159–170
  • Ranjan OP, Shavi GV, Nayak UY, et al. Controlled release chitosan microspheres of mirtazapine: in vitro and in vivo evaluation. Arch Pharm Res 2011;34:1919–1929
  • Jiang T, Singh B, Li HS, et al. Targeted oral delivery of BmpB vaccine using porous PLGA microparticles coated with M cell homing peptide-coupled chitosan. Biomaterials 2014;35:2365–2373
  • Chan JM, Zhang L, Yuet KP, et al. PLGA–lecitin-PEG core-shell nanoparticles for controlled drug delivery. Biomaterials 2009;30:1627–1634
  • Mi FL, Shyu SS, Lin YM, et al. Chitin/PLGA blend microspheres as a biodegradable drug delivery system: a new delivery system for protein. Biomaterials 2003;24:5023–5036
  • Reed AM, Gilding DK. Biodegradable polymers for use in surgery-poly (glycolic)/poly (Iactic acid) homo and copolymers: 2. In vitro degradation. Polymer 1981;22:494–498
  • Liu X, Sun Q, Wang H, et al. Microspheres of corn protein, zein, for an ivermectin drug delivery system. Biomaterials 2005;26:109–115
  • Saravanan M, Bhaskar K, Maharajan G, Pillai KS. Ultrasonically controlled release and targeted delivery of diclofenac sodium via gelatin magnetic microspheres. Int J Pharm 2004;283:71–82
  • Haznedar S, Dortunc B. Preparation and in vitro evaluation of Eudragit microspheres containing acetazolamide. Int J Pharm 2004;269:131–140
  • Esbensen KH, Guyot D, Westad F, Houmoller LP. Multivariate data analysis: in practice: an introduction to multivariate data analysis and experimental design. Oslo: CAMO AS Publications; 2004
  • Costa P, Lobo JMS. Modeling and comparison of dissolution profiles. Eur J Pharm Sci 2001;13:123–133
  • Dash S, Murthy PN, Nath L, Chowdhury P. Kinetic modeling on drug release from controlled drug delivery systems. Acta Pol Pharm 2010;67:217–223
  • Fredenberg S, Wahlgren M, Reslow M, Axelsson A. The mechanisms of drug release in poly(lactic-co-glycolic acid)-based drug delivery systems – a review. Int J Pharm 2011;415:34–52
  • Vetchý D, Vetchá M, Rabišková M, et al. Comparison in vitro felodipine release rate from the original versus generic product with controlled release of the drug. Medicina (Kaunas) 2007;43:326–331
  • Sah H. Microencapsulation techniques using ethyl acetate as a dispersed solvent: effects of its extraction rate on the characteristics of PLGA microspheres. J Control Release 1997;47:233–245
  • Freytag T, Dashevsky A, Tillman L, et al. Improvement of the encapsulation efficiency of oligonucleotide-containing biodegradable microspheres. J Control Release 2000;69:197–207
  • Yang YY, Chung TS, Ping Ng N. Morphology, drug distribution, and in vitro release profiles of biodegradable polymeric microspheres containing protein fabricated by double-emulsion solvent extraction/evaporation method. Biomaterials 2001;22:231–241
  • Wang N, Wu XS. A novel approach to stabilization of protein drugs in poly (lactic-co-glycolic acid) microspheres using agarose hydrogel. Int J Pharm 1998;166:1–14
  • Lee TH, Wang J, Wang CH. Double-walled microspheres for the sustained release of a highly water soluble drug: characterization and irradiation studies. J Control Release 2002;83:437–452
  • Yang YY, Chung TS, Bai XL, Chan WK. Effect of preparation conditions on morphology and release profiles of biodegradable polymeric microspheres containing protein fabricated by double-emulsion method. Chem Eng Sci 2000;55:2223–2236
  • Thies C. Microcapsules and nanoparticles in medicine and pharmacy. Boca Raton: CRC press; 1992
  • Roy S, Pal M, Gupta BK. Indomethacin-loaded microspheres: design and preparation by a multiple–emulsification technique and their in vitro evaluation. Pharm Res 1992;9:1132–1136
  • Berchane NS, Carson KH, Rice-Ficht AC, Andrews MJ. Effect of meandiameter and polydispersity of PLGA microspheres on drug release: experiment and theory. Int J Pharm 2007;337:118–126
  • Berkland C, Kim K, Pack DW. PLG microsphere size controls drug release rate through several competing factors. Pharm Res 2003;20:1055–1062
  • Mollo AR, Corrigan OI. Effect of poly-hydroxy aliphatic ester polymer type on amoxycillin release from cylindrical compacts. Int J Pharm 2003;268:71–79

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.