Anti-inflammatory effects of eugenol nanoemulsion as a topical delivery system

References

• Ee SL, Duan X, Liew J, et al. Droplet size and stability of nano-emulsions produced by the temperature phase inversion method. Chem Eng J 2008;140:626–631
   Web of Science ®Google Scholar
• Shakeel F, Baboota S, Ahuja A, et al. Skin permeation mechanism of aceclofenac using novel nanoemulsion formulation. Die Pharm – Int J Pharm Sci 2008;63:580–584
   Google Scholar
• Subramanian B, Kuo F, Ada E, et al. Enhancement of anti-inflammatory property of aspirin in mice by a nano-emulsion preparation. Int Immunopharmacol 2008;8:1533–1539
   PubMed Web of Science ®Google Scholar
• Khurana S, Jain NK, Bedi PM. Nanoemulsion based gel for transdermal delivery of meloxicam: physico-chemical, mechanistic investigation. Life Sci 2013;92:383–392
   PubMed Web of Science ®Google Scholar
• Kim BS, Won M, Lee KM, et al. In vitro permeation studies of nanoemulsions containing ketoprofen as a model drug. Drug Deliv 2008;15:465–469
   PubMed Web of Science ®Google Scholar
• Bachiega TF, de Sousa JPB, Bastos JK, et al. Clove and eugenol in noncytotoxic concentrations exert immunomodulatory/anti-inflammatory action on cytokine production by murine macrophages. J Pharm Pharmacol 2012;64:610–616
   PubMed Web of Science ®Google Scholar
• Daniel AN, Sartoretto SM, Schmidt G, et al. Anti-inflammatory and antinociceptive activities A of eugenol essential oil in experimental animal models. Rev Bras Farmacogn 2009;19:212–217
   Google Scholar
• Chaudhry NMA, Tariq P. Anti-microbial activity of Cinnamomum cassia against diverse microbial flora with its nutritional and medicinal impacts. Pak J Bot 2006;38:169–174
   Web of Science ®Google Scholar
• He M, Du M, Fan M, et al. In vitro activity of eugenol against Candida albicans biofilms. Mycopathologia 2007;163:137–143
   PubMed Web of Science ®Google Scholar
• Benencia F, Courreges M. In vitro and in vivo activity of eugenol on human herpesvirus. Phytother Res 2000;14:495–500
   PubMed Web of Science ®Google Scholar
• Slameňová D, Horváthová E, Wsólová L, et al. Investigation of anti-oxidative, cytotoxic, DNA-damaging and DNA-protective effects of plant volatiles eugenol and borneol in human-derived HepG2, Caco-2 and VH10 cell lines. Mutat Res/Gen Toxicol Environ Mutagen 2009;677:46–52
   PubMed Web of Science ®Google Scholar
• Young S-C, Wang C-J, Hsu J-D, et al. Increased sensitivity of Hep G2 cells toward the cytotoxicity of cisplatin by the treatment of piper betel leaf extract. Arch Toxicol 2006;80:319–327
   PubMed Web of Science ®Google Scholar
• Bachiega TF, de Sousa JPB, Bastos JK, et al. Clove and eugenol in noncytotoxic concentrations exert immunomodulatory/anti-inflammatory action on cytokine production by murine macrophages. J Pharm Pharmacol 2012;64:610–616
   PubMed Web of Science ®Google Scholar
• Zhang P, Zhang E, Xiao M, et al. Study of anti-inflammatory activities of α-d-glucosylated eugenol. Arch Pharm Res 2013;36:109–115
   PubMed Web of Science ®Google Scholar
• Öztürk A, Özbek H. The anti-inflammatory activity of Eugenia caryophyllata essential oil: an animal model of anti-inflammatory activity. 2005;2:159–163
   Google Scholar
• Hong CH, Hur SK, Oh O-J, et al. Evaluation of natural products on inhibition of inducible cyclooxygenase (COX-2) and nitric oxide synthase (iNOS) in cultured mouse macrophage cells. J Ethnopharmacol 2002;83:153–159
   PubMed Web of Science ®Google Scholar
• Kim SS, Oh O-J, Min H-Y, et al. Eugenol suppresses cyclooxygenase-2 expression in lipopolysaccharide-stimulated mouse macrophage RAW264. 7 cells. Life Sci 2003;73:337–348
   PubMed Web of Science ®Google Scholar
• Goswami DS. Permeation enhancer for TDDS from natural and synthetic sources: a review. J Biomed Pharm Res 2013;2:19–29
   Google Scholar
• Leonard TW, Mikula KK, Schlesinger MS. Eugenol enhancement of transdermal drug delivery. Google Patents. 1989
   Google Scholar
• Zhao K, Singh J. Mechanisms of percutaneous absorption of tamoxifen by terpenes: eugenol, D-limonene and menthone. J Control Release 1998;55:253–260
   PubMed Web of Science ®Google Scholar
• Jaganathan SK, Supriyanto E. Antiproliferative and molecular mechanism of eugenol-induced apoptosis in cancer cells. Molecules 2012;17:6290–6304
   PubMed Web of Science ®Google Scholar
• Opdyke DLJ. Monographs on fragrance raw materials. Elsevier; 1979. p. 247, 376
   Google Scholar
• Hamed SF, Sadek Z, Edris A. Antioxidant and antimicrobial activities of clove bud essential oil and eugenol nanoparticles in alcohol-free microemulsion. J Oleo Sci 2011;61:641–648
   Web of Science ®Google Scholar
• Ghosh V, Saranya S, Mukherjee A, et al. Antibacterial microemulsion prevents sepsis and triggers healing of wound in wistar rats. Colloids Surf B: Biointerfaces 2013;105:152–157
   PubMed Web of Science ®Google Scholar
• Talegaonkar S, Mustafa G, Akhter S, et al. Design and development of oral oil-in-water nanoemulsion formulation bearing atorvastatin: in vitro assessment. J Disper Sci Technol 2010;31:690–701
   Web of Science ®Google Scholar
• Dasgupta S, Dey S, Choudhury S, et al. Topical delivery of aceclofenac as nanoemulsion comprising excipients having optimum emulsification capabilities: preparation, characterization and in vivo evaluation. Expert Opin Drug Deliv 2013;10:411–420
   PubMed Web of Science ®Google Scholar
• Prakash P, Gupta N. Therapeutic uses of Ocimum sanctum Linn (Tulsi) with a note on eugenol and its pharmacological actions: a short review. Indian J Physiol Pharmacol 2005;49:125–131
   PubMedGoogle Scholar
• Winter CA, Risley EA, Nuss GW. Carrageenin-induced edema in hind paw of the rat as an assay for antiinflammatory drugs. Exp Biol Med 1962;111:544–547
   Google Scholar
• Lawrence MJ, Rees GD. Microemulsion-based media as novel drug delivery systems. Adv Drug Deliv Rev 2000;45:89–121
   PubMed Web of Science ®Google Scholar
• Li P, Ghosh A, Wagner RF, et al. Effect of combined use of nonionic surfactant on formation of oil-in-water microemulsions. Int J Pharm 2005;288:27–34
   PubMed Web of Science ®Google Scholar
• Hashem FM, Shaker DS, Ghorab MK, et al. Formulation, characterization, and clinical evaluation of microemulsion containing clotrimazole for topical delivery. AAPS PharmSciTech 2011;12:879–886
   PubMed Web of Science ®Google Scholar
• Komatsu T, Sakurada T. Comparison of the efficacy and skin permeability of topical NSAID preparations used in Europe. Eur J Pharm Sci 2012;47:890–895
   PubMed Web of Science ®Google Scholar
• Silva F, Dore C, Marques C, et al. Anticoagulant activity, paw edema and pleurisy induced carrageenan: action of major types of commercial carrageenans. Carbohydr Polym 2010;79:26–33
   Web of Science ®Google Scholar