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Prehospital Emergency Care Volume 15, 2011 - Issue 2
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Focus on Trauma

The Relationship Between Out-of-Hospital Airway Management and Outcome Among Trauma Patients with Glasgow Coma Scale Scores of 8 or Less

Daniel P. Davis From the Department of Emergency Medicine (DPD), UCSD Center for Resuscitation Science, San Diego, California; the University of Washington (KMK), Seattle, Washington; Axio Research Corporation (KMK), Seattle, Washington; the Center for Policy and Research in Emergency Medicine, Department of Emergency Medicine (CDN, MD), Oregon Health & Science University, Portland, Oregon; the Department of Surgery (EMB), University of Washington, Seattle, Washington; the Department of Emergency Medicine (IS), University of Ottawa, Ottawa, Ontario, Canada; the Clinical Trials Center (GN), University of Washington, Seattle, Washington; the Department of Surgery (SS, JDK), University of Alabama at Birmingham, Birmingham, Alabama; the Division of Emergency Medicine (JD), University of Western Ontario, London, Ontario, Canada; and Parkland Memorial Hospital (JM), University of Texas Southwestern Medical Center, Dallas, Texas.Correspondence[email protected]
, MD,
Kent M. Koprowicz From the Department of Emergency Medicine (DPD), UCSD Center for Resuscitation Science, San Diego, California; the University of Washington (KMK), Seattle, Washington; Axio Research Corporation (KMK), Seattle, Washington; the Center for Policy and Research in Emergency Medicine, Department of Emergency Medicine (CDN, MD), Oregon Health & Science University, Portland, Oregon; the Department of Surgery (EMB), University of Washington, Seattle, Washington; the Department of Emergency Medicine (IS), University of Ottawa, Ottawa, Ontario, Canada; the Clinical Trials Center (GN), University of Washington, Seattle, Washington; the Department of Surgery (SS, JDK), University of Alabama at Birmingham, Birmingham, Alabama; the Division of Emergency Medicine (JD), University of Western Ontario, London, Ontario, Canada; and Parkland Memorial Hospital (JM), University of Texas Southwestern Medical Center, Dallas, Texas.
, MS,
Craig D. Newgard From the Department of Emergency Medicine (DPD), UCSD Center for Resuscitation Science, San Diego, California; the University of Washington (KMK), Seattle, Washington; Axio Research Corporation (KMK), Seattle, Washington; the Center for Policy and Research in Emergency Medicine, Department of Emergency Medicine (CDN, MD), Oregon Health & Science University, Portland, Oregon; the Department of Surgery (EMB), University of Washington, Seattle, Washington; the Department of Emergency Medicine (IS), University of Ottawa, Ottawa, Ontario, Canada; the Clinical Trials Center (GN), University of Washington, Seattle, Washington; the Department of Surgery (SS, JDK), University of Alabama at Birmingham, Birmingham, Alabama; the Division of Emergency Medicine (JD), University of Western Ontario, London, Ontario, Canada; and Parkland Memorial Hospital (JM), University of Texas Southwestern Medical Center, Dallas, Texas.
, MD, MPH,
Mohamud Daya From the Department of Emergency Medicine (DPD), UCSD Center for Resuscitation Science, San Diego, California; the University of Washington (KMK), Seattle, Washington; Axio Research Corporation (KMK), Seattle, Washington; the Center for Policy and Research in Emergency Medicine, Department of Emergency Medicine (CDN, MD), Oregon Health & Science University, Portland, Oregon; the Department of Surgery (EMB), University of Washington, Seattle, Washington; the Department of Emergency Medicine (IS), University of Ottawa, Ottawa, Ontario, Canada; the Clinical Trials Center (GN), University of Washington, Seattle, Washington; the Department of Surgery (SS, JDK), University of Alabama at Birmingham, Birmingham, Alabama; the Division of Emergency Medicine (JD), University of Western Ontario, London, Ontario, Canada; and Parkland Memorial Hospital (JM), University of Texas Southwestern Medical Center, Dallas, Texas.
, MD, MS,
Eileen M. Bulger From the Department of Emergency Medicine (DPD), UCSD Center for Resuscitation Science, San Diego, California; the University of Washington (KMK), Seattle, Washington; Axio Research Corporation (KMK), Seattle, Washington; the Center for Policy and Research in Emergency Medicine, Department of Emergency Medicine (CDN, MD), Oregon Health & Science University, Portland, Oregon; the Department of Surgery (EMB), University of Washington, Seattle, Washington; the Department of Emergency Medicine (IS), University of Ottawa, Ottawa, Ontario, Canada; the Clinical Trials Center (GN), University of Washington, Seattle, Washington; the Department of Surgery (SS, JDK), University of Alabama at Birmingham, Birmingham, Alabama; the Division of Emergency Medicine (JD), University of Western Ontario, London, Ontario, Canada; and Parkland Memorial Hospital (JM), University of Texas Southwestern Medical Center, Dallas, Texas.
, MD,
Ian Stiell From the Department of Emergency Medicine (DPD), UCSD Center for Resuscitation Science, San Diego, California; the University of Washington (KMK), Seattle, Washington; Axio Research Corporation (KMK), Seattle, Washington; the Center for Policy and Research in Emergency Medicine, Department of Emergency Medicine (CDN, MD), Oregon Health & Science University, Portland, Oregon; the Department of Surgery (EMB), University of Washington, Seattle, Washington; the Department of Emergency Medicine (IS), University of Ottawa, Ottawa, Ontario, Canada; the Clinical Trials Center (GN), University of Washington, Seattle, Washington; the Department of Surgery (SS, JDK), University of Alabama at Birmingham, Birmingham, Alabama; the Division of Emergency Medicine (JD), University of Western Ontario, London, Ontario, Canada; and Parkland Memorial Hospital (JM), University of Texas Southwestern Medical Center, Dallas, Texas.
, MD,
Graham Nichol From the Department of Emergency Medicine (DPD), UCSD Center for Resuscitation Science, San Diego, California; the University of Washington (KMK), Seattle, Washington; Axio Research Corporation (KMK), Seattle, Washington; the Center for Policy and Research in Emergency Medicine, Department of Emergency Medicine (CDN, MD), Oregon Health & Science University, Portland, Oregon; the Department of Surgery (EMB), University of Washington, Seattle, Washington; the Department of Emergency Medicine (IS), University of Ottawa, Ottawa, Ontario, Canada; the Clinical Trials Center (GN), University of Washington, Seattle, Washington; the Department of Surgery (SS, JDK), University of Alabama at Birmingham, Birmingham, Alabama; the Division of Emergency Medicine (JD), University of Western Ontario, London, Ontario, Canada; and Parkland Memorial Hospital (JM), University of Texas Southwestern Medical Center, Dallas, Texas.
, MD,
Shannon Stephens From the Department of Emergency Medicine (DPD), UCSD Center for Resuscitation Science, San Diego, California; the University of Washington (KMK), Seattle, Washington; Axio Research Corporation (KMK), Seattle, Washington; the Center for Policy and Research in Emergency Medicine, Department of Emergency Medicine (CDN, MD), Oregon Health & Science University, Portland, Oregon; the Department of Surgery (EMB), University of Washington, Seattle, Washington; the Department of Emergency Medicine (IS), University of Ottawa, Ottawa, Ontario, Canada; the Clinical Trials Center (GN), University of Washington, Seattle, Washington; the Department of Surgery (SS, JDK), University of Alabama at Birmingham, Birmingham, Alabama; the Division of Emergency Medicine (JD), University of Western Ontario, London, Ontario, Canada; and Parkland Memorial Hospital (JM), University of Texas Southwestern Medical Center, Dallas, Texas.
, EMT-P,
Jonathan Dreyer From the Department of Emergency Medicine (DPD), UCSD Center for Resuscitation Science, San Diego, California; the University of Washington (KMK), Seattle, Washington; Axio Research Corporation (KMK), Seattle, Washington; the Center for Policy and Research in Emergency Medicine, Department of Emergency Medicine (CDN, MD), Oregon Health & Science University, Portland, Oregon; the Department of Surgery (EMB), University of Washington, Seattle, Washington; the Department of Emergency Medicine (IS), University of Ottawa, Ottawa, Ontario, Canada; the Clinical Trials Center (GN), University of Washington, Seattle, Washington; the Department of Surgery (SS, JDK), University of Alabama at Birmingham, Birmingham, Alabama; the Division of Emergency Medicine (JD), University of Western Ontario, London, Ontario, Canada; and Parkland Memorial Hospital (JM), University of Texas Southwestern Medical Center, Dallas, Texas.
, MD,
Joseph Minei From the Department of Emergency Medicine (DPD), UCSD Center for Resuscitation Science, San Diego, California; the University of Washington (KMK), Seattle, Washington; Axio Research Corporation (KMK), Seattle, Washington; the Center for Policy and Research in Emergency Medicine, Department of Emergency Medicine (CDN, MD), Oregon Health & Science University, Portland, Oregon; the Department of Surgery (EMB), University of Washington, Seattle, Washington; the Department of Emergency Medicine (IS), University of Ottawa, Ottawa, Ontario, Canada; the Clinical Trials Center (GN), University of Washington, Seattle, Washington; the Department of Surgery (SS, JDK), University of Alabama at Birmingham, Birmingham, Alabama; the Division of Emergency Medicine (JD), University of Western Ontario, London, Ontario, Canada; and Parkland Memorial Hospital (JM), University of Texas Southwestern Medical Center, Dallas, Texas.
, MD &
Jeffrey D. Kerby From the Department of Emergency Medicine (DPD), UCSD Center for Resuscitation Science, San Diego, California; the University of Washington (KMK), Seattle, Washington; Axio Research Corporation (KMK), Seattle, Washington; the Center for Policy and Research in Emergency Medicine, Department of Emergency Medicine (CDN, MD), Oregon Health & Science University, Portland, Oregon; the Department of Surgery (EMB), University of Washington, Seattle, Washington; the Department of Emergency Medicine (IS), University of Ottawa, Ottawa, Ontario, Canada; the Clinical Trials Center (GN), University of Washington, Seattle, Washington; the Department of Surgery (SS, JDK), University of Alabama at Birmingham, Birmingham, Alabama; the Division of Emergency Medicine (JD), University of Western Ontario, London, Ontario, Canada; and Parkland Memorial Hospital (JM), University of Texas Southwestern Medical Center, Dallas, Texas.
 show all
Pages 184-192 | Received 18 Feb 2010, Accepted 16 Nov 2010, Published online: 10 Feb 2011

References

  • Badjatia N, Carney N, Crocco TJ, Guidelines for prehospital management of traumatic brain injury. Prehosp Emerg Care. 2008;12(suppl 1):1–52.
  • McDonald CC, Bailey B. Prehospital use of neuromuscular-blocking agents in the United States. Prehosp Emerg Care. 1998;2:29–32.
  • Bochicchio GV, Ilahi O, Joshi M, Bochicchio K, Scalea TM. Endotracheal intubation in the field does not improve outcome in trauma patients who present without lethal traumatic brain injury. J Trauma. 2003;54:307–11.
  • Davis DP, Peay J, Sise MJ, The impact of prehospital endotracheal intubation on outcome in moderate-to-severe traumatic brain injury. J Trauma. 2005;58:933–9.
  • Eckstein M, Chan L, Schneir A, Palmer R. Effect of prehospital advanced life support on outcomes of major trauma patients. J Trauma. 2000;48:64–8.
  • Murray JA, Demetriades D, Berne TV, Prehospital intubation in patients with severe head injury. J Trauma. 2000;49:1065–70.
  • Wang HE, Peitzman AD, Cassidy LD, Adelson PD, Yealy DM. Prehospital endotracheal intubation and outcome after traumatic brain injury. Ann Emerg Med. 2004;44:439–50.
  • Stiell I, Nesbitt LP, Pickett W, The OPALS major trauma study: impact of advanced life-support on survival and morbidity. Can Med Assoc J. 2008;178:1141–52.
  • Bozeman WP, Idris AH. Intracranial pressure changes during rapid sequence intubation: a swine model. J Trauma. 2005;58:278–83.
  • Warner KJ, Cuschieri J, Copass MK, Jurkovich GJ, Bulger EM. The impact of prehospital ventilation on outcome after severe traumatic brain injury. J Trauma. 2007;62:1330–8.
  • Davis DP, Dunford JV, Poste JC, The impact of hypoxia and hyperventilation on outcome following paramedic rapid sequence intubation of severely head-injured patients. J Trauma. 2004;57:1–8; discussion 8–10.
  • Davis DP, Garberson LA, Andrusiek DL, A descriptive analysis of emergency medical service systems participating in the Resuscitation Outcomes Consortium (ROC) network. Prehosp Emerg Care. 2007;11:369–82.
  • Newgard CD, Sears GK, Rea TD, The Resuscitation Outcomes Consortium Epistry–Trauma: design, development, and implementation of a North American epidemiologic prehospital trauma registry. Resuscitation. 2008;78:170–8.
  • Champion HR, Sacco WJ, Copes WS, A revision of the trauma score. J Trauma. 1989;29:623–9.
  • Davis DP. Should invasive airway management be done in the field? Can Med Assoc J. 2008;178:1171–3.
  • Gausche M, Lewis RJ, Stratton SJ, Effect of prehospital pediatric endotracheal intubation on survival and neurological outcome: a controlled clinical trial [see comments]. JAMA. 2000;283:783–90.
  • Winchell RJ, Hoyt DB. Endotracheal intubation in the field improves survival in patients with severe head injury. Trauma Research and Education Foundation of San Diego. Arch Surg. 1997;132:592–7.
  • Bulger EM, Copass MK, Sabath DR, Maier RV, Jurkovich GJ. The use of neuromuscular blocking agents to facilitate prehospital intubation does not impair outcome after traumatic brain injury. J Trauma. 2005;58:718–23.
  • Cudnik MT, Newgard CD, Daya M, Jui J. The impact of rapid sequence intubation on trauma patient mortality in attempted prehospital intubation. J Emerg Med. 2010;38:175–81.
  • Dunford JV, Davis DP, Ochs M, Doney M, Hoyt DB. Incidence of transient hypoxia and pulse rate reactivity during paramedic rapid sequence intubation. Ann Emerg Med. 2003;42:721–8.
  • Wang HE, O'Connor RE, Schnyder ME, Barnes TA, Megargel RE. Patient status and time to intubation in the assessment of prehospital intubation performance. Prehosp Emerg Care. 2001;5:10–8.
  • Wang HE, Sweeney TA, O'Connor RE, Rubinstein H. Failed prehospital intubations: an analysis of emergency department courses and outcomes. Prehosp Emerg Care. 2001;5: 134–41.
  • Davis DP, Douglas DJ, Buono C, Dunford JV. The incidence of desaturations and hyperventilation associated with air medical rapid sequence intubation. Prehosp Emerg Care. 2005.
  • Davis DP, Heister R, Poste JC, Hoyt DB, Ochs M, Dunford JV. Ventilation patterns following paramedic rapid sequence intubation of patients with severe traumatic brain injury. Neurocrit Care. 2005;2:165–71.
  • Davis DP, Dunford JV, Ochs M, Park K, Hoyt DB. The use of quantitative end-tidal capnometry to avoid inadvertent severe hyperventilation in patients with head injury after paramedic rapid sequence intubation. J Trauma. 2004;56:808–14.
  • Davis DP, Idris AH, Sise MJ, Early ventilation and outcome in patients with moderate to severe traumatic brain injury. Crit Care Med. 2006;34:1202–8.
  • Chiumello D, Pristine G, Slutsky AS. Mechanical ventilation affects local and systemic cytokines in an animal model of acute respiratory distress syndrome. Am J Respir Care Med. 1999;160:109–16.
  • Imai Y, Parodo J, Kajikawa O, Injurious mechanical ventilation and end-organ epithelial cell apoptosis and organ dysfunction in an experimental model of acute respiratory distress syndrome. JAMA. 2003;289:2104–12.
  • Pepe P, Raedler C, Lurie KG, Wigginton JG. Emergency ventilatory management in hemorrhagic states: elemental or detrimental? J Trauma. 2003;54:1048–55.
  • Slutsky AS, Ranieri VM. Mechanical ventilation: lessons from the ARDSNet trial. Respir Res. 2000;1:73–7.
  • Tremblay L, Valenza F, Ribeiro SP, Li J, Slutsky AS. Injurious ventilatory strategies increase cytokines and c-fos m-RNA expression in an isolated rat lung model. J Clin Invest. 1997;99:944–52.
  • Tremblay LN, Miatto D, Hamid Q, Govindarajan A, Slutsky AS. Injurious ventilation induces widespread pulmonary epithelial expression of tumor necrosis factor-alpha and interleukin-6 messenger RNA. Crit Care Med. 2002;30:1693–700.
  • Uhlig S. Ventilation-induced lung injury and mechanotransduction: stretching it too far? Am J Physiol Lung Cell Mol Physiol. 2002;282:L892–L896.
  • Wilson MR, Choudhury S, Goddard ME, O'Dea KP, Nicholson AG, Takata M. High tidal volume upregulates intrapulmonary cytokines in an in vivo mouse model of ventilator-induced lung injury. J Appl Physiol. 2003;95:1385–93.
  • Zhang H, Downey GP, Suter PM, Slutsky AS, Ranieri VM. Conventional mechanical ventilation is associated with bronchoalveolar lavage-induced activation of polymorphonuclear leukocytes. Anesthesiology. 2002;97:1426–33.
  • Bao Y, Jiang J, Zhu C, Lu Y, Cai R, Ma C. Effect of hyperventilation on brain tissue oxygen pressure, carbon dioxide pressure, pH value and intracranial pressure during intracranial hypertension in pigs. Chin J Traumatol. 2000;3:210–3.
  • Forbes ML, Clark RS, Dixon CE, Augmented neuronal death in CA3 hippocampus following hyperventilation early after controlled cortical impact. J Neurosurg. 1998;88:549–56.
  • Manley GT, Hemphill JC, Morabito D, Cerebral oxygenation during hemorrhagic shock: perils of hyperventilation and the therapeutic potential of hypoventilation. J Trauma. 2000;48:1025–33.
  • Skippen P, Seear M, Poskitt K, Effect of hyperventilation on regional cerebral blood flow in head-injured children. Crit Care Med. 1997;25:1402–9.
  • Stringer WA, Hasso AN, Thompson JR, Hinshaw DB, Jordan KG. Hyperventilation-induced cerebral ischemia in patients with acute brain lesions: demonstration by xenon-enhanced CT. AJNR Am J Neuroradiol. 1993;14:475–84.
  • Chiu EH, Liu CS, Tan TY, Chang KC. Venturi mask adjuvant oxygen therapy in severe acute ischemic stroke. Arch Neurol. 2006;63:741–4.
  • Klinger G, Beyene J, Shah P, Perlman M. Do hyperoxaemia and hypocapnia add to the risk of brain injury after intrapartum asphyxia? Arch Dis Child Fetal Neonatal Ed. 2005;90(1): F49–F52.
  • Davis DP, Meade W, Sise MJ, Both hypoxemia and extreme hyperoxemia may be detrimental in patients with severe traumatic brain injury. J Neurotrauma. 2009;26:2217–23.
  • Davis DP, Fisher R, Buono C, Predictors of intubation success and therapeutic value of paramedic airway management in a large, urban EMS system. Prehosp Emerg Care. 2006;10:356–62.

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