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Original Article

Evaluation of activity and phenotype of α1-antitrypsin in a civil population with respiratory complications following exposure to sulfur mustard 20 years ago

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Pages 47-51 | Received 29 Jun 2009, Accepted 18 Aug 2009, Published online: 19 Jan 2010

References

  • Atkins K, Lodhi I, Hurley L, Hinshaw D. (2000). N-acetylcysteine and endothelial cell injury by sulfur mustard. J Appl Toxicol 20 (Suppl. 1):S125–8.
  • Brantly M, Nukiwa T, Crystal R. (1988). Molecular basis of α1-antitrypsin deficiency. Am J Med 84:13–31.
  • Carp H, Miller F, Hoidal J, Janoff A. (1982). Potential mechanism of emphysema: alpha 1-proteinase inhibitor recovered from lungs of cigarette smokers contains oxidized methionine and has decreased elastase inhibitory capacity. Proc Natl Acad Sci USA 79:2041–5.
  • Carrell R, Jeppsson J, Laurell C, Brennan S, Owen M, Vaughan L, Boswell DR. (1982). Structure and variation of human α1-antitrypsin. Nature 298:329–34.
  • Crystal R. (1989). The alpha 1-antitrypsin gene and its deficiency states. Trends Genet 5:411–17.
  • Crystal R. (1990). α1-Antitrypsin deficiency emphysema and liver disease. Genetic basis and strategies of therapy. J Clin Invest 85:1343–52.
  • DeMeo D, Silverman E. (2004). Alpha1-antitrypsin deficiency. 2: genetic aspects of alpha(1)-antitrypsin deficiency: phenotypes and genetic modifiers of emphysema risk. Thorax 59:259–64.
  • de Serres F. (2002). Worldwide racial and ethnic distribution of alpha1-antitrypsin deficiency: summary of an analysis of published genetic epidemiologic surveys. Chest 122:1818–29.
  • Fazlollahi M, Aghamohammadi A, Hosseini R, Lotfi A, Khoshdel A, Farhoudi A, Movahedi M, Gharagozlou M, Mozaffari H, Zandieh F, Mansouri M, Ghaffari J, Rezaei N. (2006). Study of alpha1-antitrypsin phenotypes frequencies in patients with primary antibody deficiency. Iranian J Allergy Asthma Immunol 5:69–74.
  • Freeman B, Transwell A. (1985). Biochemical and cellular aspects of pulmonary oxygen toxicity. Adv Free Radic Biol Med 1:133–64.
  • Gedde-Dahl TJ, Frants R, Olaisen B, Eriksson A, van Loghem E, Lamm L. (1981). The Gm–Pi linkage heterogeneity in view of Pi M subtypes. Ann Hum Genet 45:143–53.
  • Gelfand E, Cox D, Lin M, Dosch H. (1979). Severe combined immune-deficiency disease in patient with alpha 1-antitrypsin deficiency. Lancet 2:202.
  • Ghanei M, Harabdi AA. (2005). Long term consequences from exposure to sulfur mustard: a review. Inhalat Toxicol 19:51–6.
  • Ghanei M, Shohrati M, Harandi A, Eshraghi M, Aslani J, Alaeddini F, Manzoori H. (2007). Inhaled corticosteroids and long-acting beta 2-agonists in treatment of patients with chronic bronchiolitis following exposure to sulfur mustard. Inhalat Toxicol 19:889–94.
  • Jeppsson J, Franzen B. (1982). Typing of genetic variants of alpha 1-antitrypsin by electrofocusing. Clin Chem 28:219–25.
  • Lomas D, Belorgey D, Mallya M, Onda M, Kinghorn K, Sharp L, Phillips RL, Page R, Crowther DC, Miranda E. (2004). Polymerisation underlies alpha1-antitrypsin deficiency dementia and other serpinopathies. Frontiers Biosci 9:2873–91.
  • Miravitlles M, de Gracia J, Rodrigo M, Cruz M, Vendrell M, Vidal R, Morell F. (1999). Specific antibody response against the 23-valent pneumococcal vaccine in patients with alpha(1)-antitrypsin deficiency with and without bronchiectasis. Chest 116:946–52.
  • Morse J, Lebowitz M, Knudson R, Burrows B. (1977). Relation of protease inhibitor phenotypes to obstructive lung diseases in a community. N Engl J Med 296:1190–4.
  • O’Byrne P, Postma D. (1999). The many faces of airway inflammation: asthma and chronic obstructive pulmonary disease. Am J Resp Crit Care Med 159:S41–S63.
  • Ostergaard P. (1984). Alpha-1-antitrypsin levels and clinical symptoms in forty-eight children with selective IgA deficiency. Eur J Pediatr 142:276–8.
  • Phung N, Harbeck R, Helbling-Muntges C. (1983). Familial hypogammaglobulinemia. Genetic linkage with alpha 1-antitrypsin deficiency. Arch Intern Med 143:575–7.
  • Phung N, Kubo R, Spector S. (1982). Alpha 1-antitrypsin deficiency and common variable hypogammaglobulinemia in a patient with asthma. Chest 81:112–15.
  • Rappeneau S, Baeza-Squiban A. Marano F, Calvet J. (2000). Efficient protection of human bronchial epithelial cells against sulfur and nitrogen mustard cytotoxicity using drug combinations. Toxicol Sci 58:153–60.
  • Riley D, Kerr J. (1985). Oxidant injury of the extracellular matrix: potential role in the pathogenesis of pulmonary emphysema. Lung 163:1–13.
  • Sansom M, Ferry B, Sherrell Z, Chapel H. (2002). A preliminary assessment of alpha-1 antitrypsin S and Z deficiency allele frequencies in common variable immunodeficiency patients with and without bronchiectasis. Clin Exp Immunol 130:489–94.
  • Sharp H, Bridges R, Krivit W, Freier E. (1969). Cirrhosis associated with alpha-1-antitrypsin deficiency: a previously unrecognized inherited disorder. J Lab Clin Med 73:934–9.
  • Shohrati M, Aslani J, Eshraghi M, Alaedini F, Ghanei M. (2008). Therapeutic effects of N-acetyl cysteine on mustard gas exposed patients: evaluating clinical aspect in patients with impaired pulmonary function test. Resp Med 102:443–8.
  • Shohrati M, Ghanei M, Shamspour N. (2007a). Oxidative stress in lung injuries due to sulfur mustard. 44th Congress of the European Societies of Toxicology, Amsterdam Netherlands. C43.
  • Shohrati M, Peyman M, Peyman A, Davoudi M, Ghanei M. (2007b). Cutaneous and ocular late complications of sulfur mustard in Iranian veterans. Cutan Ocul Toxicol 26:73–81.
  • Southorn P, Powis G. (1988). Free radicals in medicine. II. Involvement in human disease. Mayo Clin Proc 63:390–408.
  • Stockley R. (1999). Neutrophils and protease/antiprotease imbalance. Am J Resp Crit Care Med 160:S49–S52.
  • Taggart C, Cervantes-Laurean D, Kim G, McElvaney N, Wehr N, Moss J, Levine RL. (2000). Oxidation of either methionine 351 or methionine 358 in alpha 1-antitrypsin causes loss of anti-neutrophil elastase activity. J Biol Chem 275:27258–65.

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