Advanced search
Publication Cover
Biomarkers Volume 1, 1996 - Issue 1
Submit an article Journal homepage
9
Views
7
CrossRef citations to date
0
Altmetric
Research Article

Expression of p21ras-related protein in the plasma and tissue of patients with adenomas and carcinomas of the colon

Jiin-Chyuan Luo the Division, of Environmental Health Sciences, Columbia University College of phvsicians and Surgeons and School of Public Health, 60 Haven Avenue, B-1, New York, NY, 10032, USA
,
Alfred I. Neugut the Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, PA, 15213, USA
,
Gail Garbowski the Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, PA, 15213, USA
,
Kenneth A. Forde the Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, PA, 15213, USA
,
Michael Treat the Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, PA, 15213, USA
,
Steven Smith the Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, PA, 15213, USA
,
Henry Niman the Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, PA, 15213, USA
&
Paul W. Brandt-Rauf the Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, PA, 15213, USA
 show all
Pages 29-33 | Received 12 Sep 1995, Accepted 13 Oct 1995, Published online: 27 Sep 2008

References

  • Barbacid M. Ras genes. Annual Review of Biochemistry 1987; 56: 779–827
  • Branot-Rauf P. W. Oncogene proteins as biomarkers in the molecular epidemiology of occupational carcinogenesis: the example of the ras oncogeneencoded p21 protein. International Archives of Occupational and Environmental Health 1991; 63: 1–8
  • Brandt-Rauf P. W., Niman H. L., Smith S. J. Correlation between serum oncogene protein expression and the development of neoplastic disease in a worker exposed to carcinogens. Journal of the Royal Society of Medicine 1990; 83: 594–595
  • Brandt-Ralf P. W., Smith S., Hemminki K., Kosxinen H., Vainio H., Niman H., Ford J. Serum oncoproteins and growth factors in asbestosis and silicosis patients. International Journal of Cancer 1992; 50: 881–885
  • Epelbaum R., Bartal A. H., Rmkin M., Tugendhaft N., Shalitin C. Competitive ELISA for detection of native ras gene-related products in sera of cancer patients. Journal of Clinical Laboratory Analysis 1989; 3: 209–214
  • Gallick G. E., Kurzrocx R., Kloetzer W. S., Arlinghaus R. B., Gutterman J. U. Expression of p21 ras in fresh primary and metastatic human colorectal tumors. Proceedings of the National Academy of Sciences USA 1985; 82: 1795–1799
  • Hand P. H., Vilasi V., Caruso A., Schlom J. Absolute values of ras p21 defined by direct binding liquid competition radiommunoassays. Biochimica et Biophysica Acta 1987; 908: 131–142
  • Jansson D. S., Radosevich J. A., Carney W. P., Rosen S. T., Schlom J., Staren E. D., Hyser M. J., Gould V. E. An immunohistochemical analysis of rasoncogene expression in epithelial neoplasms of the colon. Cancer 1990; 65: 1329–1337
  • Kakkanas A., Spandidos D. A. Ras p21 onco-protein in the sera of mice carrying an experimentally induced tumor and in human cancer patients. In Vivo 1990; 4: 115–120
  • Lanza G. Ras p21 oncoprotein expression in human colonic neo-plasia—an immunohistochemical study with monoclonal antibody RAP-5. Histopathology 1988; 12: 595–609
  • Luo J. C., Neugut A. I., Garbowski G., Foroe K. A., Treat M., Smith S., Carney W. P., Branot-Rauf P. W. Levels of p53 antigen in the plasma of patients with adenomas and carcinomas of the colon. Cancer Letters 1995; 91: 235–240
  • Miller F., Hermann T. M., Quish A., Pyo D. J., Szporn A., Martinelli G., Fasy T. M. Ras and c-myc protein expression in colorectal carcinoma—study ofcancer-prone patients. Diseases of the Colon and Rectum 1992; 35: 430–435
  • Perera F., Fischman H. K., Hemminki K., Brandt-Rauf P. W., Niman H. L., Smith S., Toporoff E., O'Dowd K., Tang M. X., Tm W. Y., Stoopler M. Protein binding, sister chromatid exchange and expression of oncogene proteins in patients with cisplatinum (cis ODPI-based chemotherapy. Archives of Toxicology 1990; 64: 401–406
  • Perera F. P., Hemminki K., Gryzbowska E., Motykiewicz G., Michalska J., Santella R. M., Young T.-L., Dickey C., Brandt-Rauf P. W., Devivo I., Blaner W., Tsai W.-Y., Chorazy M. Molecular and genetic damage in humans from environmental pollution in Poland. Nature 1992; 360: 256–258
  • Thor A., Hand P. H., Wunderuch D., Caruso A., Muraro R., Schlom J. Monoclonal antibodies define differentras gene expression in malignant and benign colonic disease. Nature 1984; 311: 563–565
  • Waneeo H. J. Colorectal Cancer. Mosby, St Louis, MO 1993
  • Weissfeld J. L., Larsen R. D., Niman H. L., Kuller L. H. Evaluation of oncogene-related proteins in serum. Cancer Epidemiology, Biornarkers and Prevention 1994; 3: 57–62

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.