Plasma and synovial fluid connective tissue growth factor levels are correlated with disease severity in patients with knee osteoarthritis

References

• Anitua E, Sánchez M, de la Fuente M, Azofra J, Zalduendo M, Aguirre JJ, Andía I. (2009). Relationship between Investigative Biomarkers and Radiographic Grading in Patients with Knee Osteoarthritis. Int J Rheumatol 2009:747432.
   PubMedGoogle Scholar
• Blaney Davidson EN, Vitters EL, Mooren FM, Oliver N, Berg WB, van der Kraan PM. (2006). Connective tissue growth factor/CCN2 overexpression in mouse synovial lining results in transient fibrosis and cartilage damage. Arthritis Rheum 54:1653–1661.
   PubMed Web of Science ®Google Scholar
• Bork P. (1993). The modular architecture of a new family of growth regulators related to connective tissue growth factor. FEBS Lett 327:125–130.
   PubMed Web of Science ®Google Scholar
• Cicha I, Goppelt-Struebe M. (2009). Connective tissue growth factor: context-dependent functions and mechanisms of regulation. Biofactors 35:200–208.
   PubMed Web of Science ®Google Scholar
• Dendooven A, Gerritsen KG, Nguyen TQ, Kok RJ, Goldschmeding R. (2011). Connective tissue growth factor (CTGF/CCN2) ELISA: a novel tool for monitoring fibrosis. Biomarkers 16:289–301.
   PubMed Web of Science ®Google Scholar
• Fujisawa T, Hattori T, Ono M, Uehara J, Kubota S, Kuboki T, Takigawa M. (2008). CCN family 2/connective tissue growth factor (CCN2/CTGF) stimulates proliferation and differentiation of auricular chondrocytes. Osteoarthr Cartil 16:787–795.
   Google Scholar
• Honsawek S, Chayanupatkul M, Tanavalee A, Sakdinakiattikoon M, Deepaisarnsakul B, Yuktanandana P, Ngarmukos S. (2009). Relationship of plasma and synovial fluid BMP-7 with disease severity in knee osteoarthritis patients: a pilot study. Int Orthop 33:1171–1175.
   PubMed Web of Science ®Google Scholar
• Huang K, Du G, Li L, Liang H, Zhang B. (2012). Association of chemerin levels in synovial fluid with the severity of knee osteoarthritis. Biomarkers 17:16–20.
   PubMed Web of Science ®Google Scholar
• Hurter K, Spreng D, Rytz U, Schawalder P, Ott-Knüsel F, Schmökel H. (2005). Measurements of C-reactive protein in serum and lactate dehydrogenase in serum and synovial fluid of patients with osteoarthritis. Vet J 169:281–285.
   PubMed Web of Science ®Google Scholar
• Ivkovic S, Yoon BS, Popoff SN, Safadi FF, Libuda DE, Stephenson RC, Daluiski A, Lyons KM. (2003). Connective tissue growth factor coordinates chondrogenesis and angiogenesis during skeletal development. Development 130:2779–2791.
   PubMed Web of Science ®Google Scholar
• Kanaan RA, Aldwaik M, Al-Hanbali OA. (2006). The role of connective tissue growth factor in skeletal growth and development. Med Sci Monit 12:RA277–RA281.
   Google Scholar
• Kellgren JH, Lawrence JS. (1957). Radiological assessment of osteo-arthrosis. Ann Rheum Dis 16:494–502.
   PubMed Web of Science ®Google Scholar
• Krachler M, Domej W. (2001). Clinical laboratory parameters in osteoarthritic knee-joint effusions correlated to trace element concentrations. Biol Trace Elem Res 79:139–148.
   Google Scholar
• Kraus VB. (1997). Pathogenesis and treatment of osteoarthritis. Med Clin North Am 81:85–112.
   PubMed Web of Science ®Google Scholar
• Ku JH, Lee CK, Joo BS, An BM, Choi SH, Wang TH, Cho HL. (2009). Correlation of synovial fluid leptin concentrations with the severity of osteoarthritis. Clin Rheumatol 28:1431–1435.
   PubMed Web of Science ®Google Scholar
• Kubota S, Takigawa M. (2007). Role of CCN2/CTGF/Hcs24 in bone growth. Int Rev Cytol 257:1–41.
   PubMedGoogle Scholar
• Kumar S, Connor JR, Dodds RA, Halsey W, Van Horn M, Mao J, Sathe G, Mui P, Agarwal P, Badger AM, Lee JC, Gowen M, Lark MW. (2001). Identification and initial characterization of 5000 expressed sequenced tags (ESTs) each from adult human normal and osteoarthritic cartilage cDNA libraries. Osteoarthr Cartil 9:641–653.
   PubMed Web of Science ®Google Scholar
• Lee YT, Shao HJ, Wang JH, Liu HC, Hou SM, Young TH. (2010). Hyaluronic acid modulates gene expression of connective tissue growth factor (CTGF), transforming growth factor-beta1 (TGF-beta1), and vascular endothelial growth factor (VEGF) in human fibroblast-like synovial cells from advanced-stage osteoarthritis in vitro. J Orthop Res 28:492–496.
   PubMed Web of Science ®Google Scholar
• Masuko K, Murata M, Yudoh K, Shimizu H, Beppu M, Nakamura H, Kato T. (2010). Prostaglandin E2 regulates the expression of connective tissue growth factor (CTGF/CCN2) in human osteoarthritic chondrocytes via the EP4 receptor. BMC Res Notes 3:5.
   Google Scholar
• Nakao K, Kubota S, Doi H, Eguchi T, Oka M, Fujisawa T, Nishida T, Takigawa M. (2005). Collaborative action of M-CSF and CTGF/CCN2 in articular chondrocytes: possible regenerative roles in articular cartilage metabolism. Bone 36:884–892.
   Google Scholar
• Nishida T, Kubota S, Nakanishi T, Kuboki T, Yosimichi G, Kondo S, Takigawa M. (2002). CTGF/Hcs24, a hypertrophic chondrocyte-specific gene product, stimulates proliferation and differentiation, but not hypertrophy of cultured articular chondrocytes. J Cell Physiol 192:55–63.
   PubMed Web of Science ®Google Scholar
• Nishida T, Kubota S, Kojima S, Kuboki T, Nakao K, Kushibiki T, Tabata Y, Takigawa M. (2004). Regeneration of defects in articular cartilage in rat knee joints by CCN2 (connective tissue growth factor). J Bone Miner Res 19:1308–1319.
   PubMedGoogle Scholar
• Omoto S, Nishida K, Yamaai Y, Shibahara M, Nishida T, Doi T, Asahara H, Nakanishi T, Inoue H, Takigawa M. (2004). Expression and localization of connective tissue growth factor (CTGF/Hcs24/CCN2) in osteoarthritic cartilage. Osteoarthr Cartil 12:771–778.
   Google Scholar
• Perbal B. (2004). CCN proteins: multifunctional signalling regulators. Lancet 363:62–64.
   PubMed Web of Science ®Google Scholar
• Saetan N, Honsawek S, Tanavalee A, Tantavisut S, Yuktanandana P, Parkpian V. (2011). Association of plasma and synovial fluid interferon-? inducible protein-10 with radiographic severity in knee osteoarthritis. Clin Biochem 44:1218–1222.
   Google Scholar
• Takigawa M, Nakanishi T, Kubota S, Nishida T. (2003). Role of CTGF/HCS24/ecogenin in skeletal growth control. J Cell Physiol 194:256–266.
   PubMed Web of Science ®Google Scholar
• Walter EL, Spreng D, Schmöckel H, Schawalder P, Tschudi P, Friess AE, Stoffel MH. (2007). Distribution of lactate dehydrogenase in healthy and degenerative canine stifle joint cartilage. Histochem Cell Biol 128:7–18.
   Google Scholar
• Zhang H, Liew CC, Marshall KW. (2002). Microarray analysis reveals the involvement of beta-2 microglobulin (B2M) in human osteoarthritis. Osteoarthr Cartil 10:950–960.
   PubMed Web of Science ®Google Scholar