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Biomarkers Volume 19, 2014 - Issue 1
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Research Article

TGF-α gene variations and increased susceptibility of gastric cancer in an eastern Chinese Han population

Juan WuDiscipline of Chinese and Western Integrative Medicine, Nanjing University of Chinese Medicine NanjingChina
,
Shujuan TongDiscipline of Chinese and Western Integrative Medicine, Nanjing University of Chinese Medicine NanjingChina
,
Zhen ZhanDiscipline of Chinese and Western Integrative Medicine, Nanjing University of Chinese Medicine NanjingChinaCorrespondence[email protected]
,
Junfeng ZhangDiscipline of Chinese and Western Integrative Medicine, Nanjing University of Chinese Medicine NanjingChina
,
Che ChenDepartment of Digestive Tumor Surgery, Jiangsu Province Hospital of Traditional Chinese Medicine, Affiliated Hospital of Nanjing University of Traditional Chinese Medicine NanjingChina
,
Shouyou HuDepartment of Oncology, Traditional Chinese Medicine Hospital of Jiangsu Province NanjingChina
&
Ruiping WangDepartment of Oncology, Traditional Chinese Medicine Hospital of Jiangsu Province NanjingChina
 show all
Pages 9-15 | Received 06 Sep 2013, Accepted 23 Oct 2013, Published online: 18 Nov 2013

References

  • Carneiro F, Chaves P. (2006). Pathologic risk factors of adenocarcinoma of the gastric cardia and gastroesophageal junction. Surg Oncol Clin N Am 15:697–714
  • Chen Y, Song Y, Wang Z, et al. (2010). Altered expression of MiR-148a and MiR-152 in gastrointestinal cancers and its clinical significance. J Gastrointest Surg 14:1170–9
  • Choi JH, Kim HC, Lim HY, et al. (1999). Detection of transforming growth factor-alpha in the serum of gastric carcinoma patients. Oncology 57:236–41
  • Cortazar D, Kunz C, Selfridge J, et al. (2011). Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability. Nature 470:419–23
  • Crew KD, Neugut AI. (2004). Epidemiology of upper gastrointestinal malignancies. Semin Oncol 31:450–64
  • Derynck R. (1988). Transforming growth factor alpha. Cell 54:593–5
  • Espinoza LA, Tone LG, Neto JB, et al. (2004). Enhanced TGFalpha-EGFR expression and P53 gene alterations contributes to gastric tumors aggressiveness. Cancer Lett 212:33–41
  • Koyama S, Ikeda K, Sato M, et al. (1997). Transforming growth factor-alpha (TGF alpha)-producing gastric carcinoma with acanthosis nigricans: an endocrine effect of TGF alpha in the pathogenesis of cutaneous paraneoplastic syndrome and epithelial hyperplasia of the esophagus. J Gastroenterol 32:71–7
  • Lam AK, Lau KK, Gopalan V, et al. (2011). Quantitative analysis of the expression of TGF-alpha and EGFR in papillary thyroid carcinoma: clinicopathological relevance. Pathology 43:40–7
  • Liu C, Woo A, Tsao MS. (1990). Expression of transforming growth factor-alpha in primary human colon and lung carcinomas. Br J Cancer 62:425–9
  • Parkin DM, Bray F, Ferlay J, Pisani P. (2005). Global cancer statistics, 2002. CA Cancer J Clin 55:74–108
  • Stock M, Otto F. (2005). Gene deregulation in gastric cancer. Gene 360:1–19
  • Stoll C, Qian JF, Feingold J, Sauvage P, May E. (1993). Genetic variation in transforming growth factor alpha: possible association of BamHI polymorphism with bilateral sporadic cleft lip and palate. Hum Genet 92:81–2
  • Sull JW, Liang KY, Hetmanski JB, et al. (2009). Evidence that TGFA influences risk to cleft lip with/without cleft palate through unconventional genetic mechanisms. Hum Genet 126:385–94
  • Tahara H, Sato K, Yamazaki Y, et al. (2013). Transforming growth factor-alpha activates pancreatic stellate cells and may be involved in matrix metalloproteinase-1 upregulation. Lab Invest 93:720–32
  • Todaro GJ, Fryling C, de Larco JE. (1980). Transforming growth factors produced by certain human tumor cells: polypeptides that interact with epidermal growth factor receptors. Proc Natl Acad Sci USA 77:5258–62
  • Uemura N, Okamoto S, Yamamoto S, et al. (2001). Helicobacter pylori infection and the development of gastric cancer. N Engl J Med 345:784–9
  • Ushijima T, Sasako M. (2004). Focus on gastric cancer. Cancer Cell 5:121–5
  • Wu MS, Shun CT, Wang HP, et al. (1997). Genetic alterations in gastric cancer: relation to histological subtypes, tumor stage, and Helicobacter pylori infection. Gastroenterology 112:1457–65
  • Xu Y, Ma H, Yu H, et al. (2013). The miR-184 binding-site rs8126 T>C polymorphism in TNFAIP2 is associated with risk of gastric cancer. PLoS One 8:e64973
  • Yang P, Tang R, Zhu J, et al. (2013). A functional variant at miR-24 binding site in B7-H2 alters susceptibility to gastric cancer in a Chinese Han population. Mol Immunol 56:98–103
  • Yang Q, Jie Z, Ye S, et al. (2012). Genetic variations in miR-27a gene decrease mature miR-27a level and reduce gastric cancer susceptibility. Oncogene. [Online] Available from: http://www.nature.com/onc/journal/vaop/ncurrent/full/onc2012569a.html [last accessed 6 Sep 2013]
  • Yonemura Y, Takamura H, Ninomiya I, et al. (1992). Interrelationship between transforming growth factor-alpha and epidermal growth factor receptor in advanced gastric cancer. Oncology 49:157–61
  • Zhan Z, Wu J, Zhang JF, et al. (2012). CDH1 gene polymorphisms, plasma CDH1 levels and risk of gastric cancer in a Chinese population. Mol Biol Rep 39:8107–13
  • Zheng L, Wang L, Ajani J, Xie K. (2004). Molecular basis of gastric cancer development and progression. Gastric Cancer 7:61–77
  • Zhu C, Li J, Ding Q, et al. (2013). miR-152 controls migration and invasive potential by targeting TGFalpha in prostate cancer cell lines. prostate 73:1082–9

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