157
Views
5
CrossRef citations to date
0
Altmetric
Research Article

Low holo-transcobalamin levels are prevalent in vegetarians and is associated with coronary artery disease in Indian population

, , , , , & show all
Pages 436-440 | Received 20 Mar 2015, Accepted 29 Jan 2016, Published online: 21 Mar 2016

References

  • Ables GP, Ouattara A, Hampton TG, et al. (2015). Dietary methionine restriction in mice elicits an adaptive cardiovascular response to hyperhomocysteinemia. Sci Rep 5:8886.
  • Ahmad S, Kumar KA, Basak T, et al. (2013). PPAR signaling pathway is a key modulator of liver proteome in pups born to vitamin B(12) deficient rats. J Proteomics 91:297–308.
  • Catena C, Colussi G, Nait F, et al. (2014). Elevated homocysteine levels are associated with the metabolic syndrome and cardiovascular events in hypertensive patients. Am J Hypertens 28:943–50.
  • Cinemre H, Serinkan Cinemre BF, Cekdemir D, et al. (2015). Diagnosis of vitamin B12 deficiency in patients with myeloproliferative disorders. J Investig Med 63:636–40.
  • Garg G, Kumar J, Tanwar VS, et al. (2012). Polymorphisms in transcobalamin II gene is associated with coronary artery disease in Indian population. Biomarkers 17:119–24.
  • Gaziano TA, Bitton A, Anand S, et al. (2010). Growing epidemic of coronary heart disease in low- and middle-income countries. Curr Probl Cardiol 35:72–115.
  • Ghiselli A, D'amicis A, Giacosa A. (1997). The antioxidant potential of the Mediterranean diet. Eur J Cancer Prev 6:S15–19.
  • Greibe E, Nexo E. (2011). Vitamin B12 absorption judged by measurement of holotranscobalamin, active vitamin B12: evaluation of a commercially available EIA kit. Clin Chem Lab Med 49:1883–5.
  • Hanumante NM, Wadia RS, Deshpande SS, et al. (2008). Vitamin B12 and homocysteine status in asymptomatic Indian toddlers. Indian J Pediatr 75:751–3.
  • Herrmann W, Schorr H, Obeid R, Geisel J. (2003). Vitamin B-12 status, particularly holotranscobalamin II and methylmalonic acid concentrations, and hyperhomocysteinemia in vegetarians. Am J Clin Nutr 78:131–6.
  • Hooshmand B, Solomon A, Kareholt I, et al. (2010). Homocysteine and holotranscobalamin and the risk of Alzheimer disease: a longitudinal study. Neurology 75:1408–14.
  • Issac TG, Soundarya S, Christopher R, Chandra SR. (2015). Vitamin B12 deficiency: an important reversible co-morbidity in neuropsychiatric manifestations. Indian J Psychol Med 37:26–9.
  • Karthikeyan G, Teo KK, Islam S, et al. (2009). Lipid profile, plasma apolipoproteins, and risk of a first myocardial infarction among Asians: an analysis from the INTERHEART study. J Am Coll Cardiol 53:244–53.
  • Key TJ, Fraser GE, Thorogood M, et al. (1999). Mortality in vegetarians and nonvegetarians: detailed findings from a collaborative analysis of 5 prospective studies. Am J Clin Nutr 70:516s–24s.
  • Khare A, Lopez M, Gogtay J. (2006). Homocysteine, B vitamins, and cardiovascular disease. N Engl J Med 355:209–11.
  • Krishnaveni GV, Hill JC, Veena SR, et al. (2009). Low plasma vitamin B12 in pregnancy is associated with gestational 'diabesity' and later diabetes. Diabetologia 52:2350–8.
  • Kullo IJ, Cooper LT. (2010). Early identification of cardiovascular risk using genomics and proteomics. Nat Rev Cardiol 7:309–17.
  • Kumar J, Garg G, Kumar A, et al. (2009a). Single nucleotide polymorphisms in homocysteine metabolism pathway genes: association of CHDH A119C and MTHFR C677T with hyperhomocysteinemia. Circ Cardiovasc Genet 2:599–606.
  • Kumar J, Garg G, Sundaramoorthy E, et al. (2009b). Vitamin B12 deficiency is associated with coronary artery disease in an Indian population. Clin Chem Lab Med 47:334–8.
  • Lahner E, Gentile G, Purchiarioni F, et al. (2015). Single nucleotide polymorphisms related to vitamin B serum levels in autoimmune gastritis patients with or without pernicious anaemia. Dig Liver Dis 47:285–90.
  • Lee JY, Lee BS, Shin DJ, et al. (2013). A genome-wide association study of a coronary artery disease risk variant. J Hum Genet 58:120–6.
  • Mccarthy MI, Abecasis GR, Cardon LR, et al. (2008). Genome-wide association studies for complex traits: consensus, uncertainty and challenges. Nat Rev Genet 9:356–69.
  • Miller JW, Garrod MG, Allen LH, et al. (2009). Metabolic evidence of vitamin B-12 deficiency, including high homocysteine and methylmalonic acid and low holotranscobalamin, is more pronounced in older adults with elevated plasma folate. Am J Clin Nutr 90:1586–92.
  • Misra A, Vikram NK, Pandey RM, et al. (2002). Hyperhomocysteinemia, and low intakes of folic acid and vitamin B12 in urban North India. Eur J Nutr 41:68–77.
  • Nexo E, Hoffmann-Lucke E. (2011). Holotranscobalamin, a marker of vitamin B-12 status: analytical aspects and clinical utility. Am J Clin Nutr 94:359S–65S.
  • Padmanabhan S, Hastie C, Prabhakaran D, Dominczak AF. (2010). Genomic approaches to coronary artery disease. Indian J Med Res 132:567–78.
  • Preuss M, Konig IR, Thompson JR, et al. (2010). Design of the coronary artery disease genome-wide replication and meta-analysis (CARDIoGRAM) study: a genome-wide association meta-analysis involving more than 22,000 cases and 60,000 controls. Circ Cardiovasc Genet 3:475–83.
  • Riedel BM, Molloy AM, Meyer K, et al. (2011). Transcobalamin polymorphism 67A-G, but not 776C-G, affects serum holotranscobalamin in a cohort of healthy middle-aged men and women. J Nutr 141:1784–90.
  • Serefhanoglu S, Aydogdu I, Kekilli E, et al. (2008). Measuring holotranscobalamin II, an early indicator of negative vitamin B12 balance, by radioimmunoassay in patients with ischemic cerebrovascular disease. Ann Hematol 87:391–5.
  • Sharma P, Garg G, Kumar A, et al. (2014). Genome wide DNA methylation profiling for epigenetic alteration in coronary artery disease patients. Gene 541:31–40.
  • Sharma P, Kumar J, Garg G, et al. (2008). Detection of altered global DNA methylation in coronary artery disease patients. DNA Cell Biol 27:357–65.
  • Sharma P, Senthilkumar RD, Brahmachari V, et al. (2006). Mining literature for a comprehensive pathway analysis: a case study for retrieval of homocysteine related genes for genetic and epigenetic studies. Lipids Health Dis 5:1. doi: 10.1186/1476-511X-5-1.
  • Singh G, Le D, Schnabl K, et al. (2016). Vitamin B12 deficiency in infancy: the case for screening. Pediatr Blood Cancer 63:740–2.
  • Stein EA, Lane M, Laskarzewski P. (1998). Comparison of statins in hypertriglyceridemia. Am J Cardiol 81:66B–9B.
  • Stranger BE, Stahl EA, Raj T. (2011). Progress and promise of genome-wide association studies for human complex trait genetics. Genetics 187:367–83.
  • Yajnik CS, Deshpande SS, Jackson AA, et al. (2008). Vitamin B12 and folate concentrations during pregnancy and insulin resistance in the offspring: the Pune maternal nutrition study. Diabetologia 51:29–38.
  • Yetley EA, Pfeiffer CM, Phinney KW, et al. (2011). Biomarkers of vitamin B-12 status in NHANES: a roundtable summary. Am J Clin Nutr 94:313S–21S.
  • Zeller T, Blankenberg S, Diemert P. (2012). Genomewide association studies in cardiovascular disease-an update 2011. Clin Chem 58:92–103.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.