References
- Alessandro A, Zolla L. (2012). Metabolomics and cancer drug discovery: let the cells do the talking. Drug Discov Today 17:6443–6446.
- Argelia L, Craig L. (2007). Pathway engineering of the plant vitamin C metabolic network. In: Verpoorte R, Alfermann AW, Johnson TS, eds. Applications of plant metabolic engineering. Netherlands: Springer, 197–217.
- Bahety P, Tan YM, Hong Y, et al. (2014). Metabotyping of docosahexaenoic acid-treated Alzheimer's disease cell model. PLoS One 9:e90123.
- Cao B, Li M, Zha W, et al. (2013). Metabolomic approach to evaluating adriamycin pharmacodynamics and resistance in breast cancer cells. Metabolomics 9:960–73.
- Cheel J, Theobuloz C, Rodriaguez J, et al. (2005). Free radical scavengers and antioxidants from lemongrass. J Agric Food Chem 53:2511–17.
- Chen GC, Lu DB, Pang Z, Liu QF. (2013). Vitamin C intake, circulating vitamin C and risk of stroke: a meta-analysis of prospective studies. J Am Heart Assoc 2:e000329.
- Chen P, Liu Z, Liu S, et al. (2009). A LC–MS/MS method for the analysis of intracellular nucleoside triphosphate levels. Pharm Res 26:1504–15.
- Deng W, Wang Y, Liu Z, et al. (2014). HemI: a toolkit for illustrating heatmaps. PLoS One 9:e111988.
- Dettmer K, Nürnberger N, Kaspar H, et al. (2011). Metabolite extraction from adherently growing mammalian cells for metabolomics studies: optimization of harvesting and extraction protocols. Anal Bioanal Chem 399:1127–39.
- Dimitrov MD, Pesheva MG, et al. (2013). New cell-based assay indicates dependence of antioxidant biological activity on the origin of reactive oxygen species. J Agric Food Chem 61:4344–51.
- Ding H, Inoue S, Ljubimov AV, et al. (2010). Inhibition of brain tumor growth by intravenous poly (β-l-malic acid) nanobioconjugate with pH-dependent drug release. Proc Natl Acad Sci 107:18143–8.
- Egel P, Sharoyko VV, et al. (2013). Time-resolved metabolomics analysis of β-cells implicates the pentose phosphate pathway in the control of insulin release. Biochem Soc 450:595–605.
- Filaire E, Dupuisa C, Galvaing G, et al. (2013). Lung cancer: what are the links with oxidative stress, physical activity and nutrition. Lung Cancer 82:383–9.
- Förstermann U. (2010). Nitric oxide and oxidative stress in vascular disease. Pflugers Arch 459:923–39.
- Galasko D, Montine TJ. (2010). Biomarkers of oxidative damage and inflammation in Alzheimer's disease. Biomark Med 4:27–36.
- Brown-Borga HM, Sharlene G, et al. (2005). Growth hormone alters methionine and glutathione metabolism in Ames dwarf mice. Mech Age Dev 126:389–98.
- Holly M, Brown-Borga, Sharlene G, et al. (2005). Growth hormone alters methionine and glutathione metabolism in Ames dwarf mice. Mech Ageing Dev 126:389–98.
- Hu C, Hsiao C, Huang S, et al. (2004). Antioxidant activity of fermented soybean extract. J Agric Food Chem 52:5735–9.
- Jia L, Chen J, Yin P, et al. (2008). Serum metabonomics study of chronic renal failure by ultra performance liquid chromatography coupled with Q-TOF mass spectrometry. Metabolomics 4:183–9.
- Joseph D, Fumio M, Atsushi I, et al. (2013). Production of indole alkaloids by metabolic engineering of the tryptophan pathway in rice. Plant Biotechnol J 11:1103–11.
- Karunakaran U, Park K. (2013). A systematic review of oxidative stress and safety of antioxidants in diabetes: focus on islets and their defense. Diabetes Metab J 37:106–12.
- Li F, Pang X, Krausz K, et al. (2013). Stable isotope- and mass spectrometry-based metabolomics as tools in drug metabolism: a study expanding tempol pharmacology. J Proteome Res 12:1369–76.
- Li PL, Sun HG, Hua YL, et al. (2015). Metabolomics study of hematopoietic function of Angelica sinensis on blood deficiency mice model. J Ethnopharmacol 26:261–9.
- Liu Y, Sun X, Di D, et al. (2011). A metabolic profiling analysis of symptomatic gout in human serum and urine using high performance liquid chromatography-diode array detector technique. Clin Chim Acta 412:2132–40.
- Monteiro M, Carvalho M, Bastos M, et al. (2014). Biomarkers in renal cell carcinoma: a metabolomics approach. Metabolomics 10:1210–22.
- Pines O, Sharona E, Elnathan N, et al. (1996). The cytosolic pathway of l-malic acid synthesis in Saccharomyces cerevisiae: the role of fumarase. Appl Microbiol Biotechnol 46:393–9.
- Sentellas S, Morales-Ibanez O, Zanuy M, et al. (2014). GSSG/GSH ratios in cryopreserved rat and human hepatocytes as a biomarker for drug induced oxidative stress. Toxicol In Vitro 28:1006–15.
- Setoyama D, Fujimura Y, Miura D. (2013). Metabolomics reveals that carnitine palmitoyltransferase-1 is a novel target for oxidative inactivation in human cells. Genes Cells 18:1107–19.
- Sumner DR, Ross R, Purdue E. (2014). Are there biological markers for wear or corrosion? A systematic review. Clin Orthopaed Relat Res 472:3728–39.
- Suzuki M, Nishiumi S, Matsubara A, et al. (2014). Metabolome analysis for discovering biomarkers of gastroenterological cancer. J Chromatogr B Analyt Technol Biomed Life Sci 966:59–69.
- Tang X, He Z, Dai Y, et al. (2010). Peptide fractionation and free radical scavenging activity of zein hydrolysate. J Agric Food Chem 58:587–93.
- Teng Q, Huang W, Collette TW, et al. (2009). A direct cell quenching method for cell-culture based metabolomics. Metabolomics 5:199–208.
- Thome J, Ehlis AC, Fallgatter AJ, et al. (2012). Biomarkers for attention-deficit/hyperactivity disorder (ADHD). A consensus report of the WFSBP task force on biological markers and the World Federation of ADHD. J Biol Psychiatry 13:379–400.
- Tianpanich K, Prachya S, Wiyakrutta S, et al. (2011). Radical scavenging and antioxidant activities of isocoumarins and a phthalide from the endophytic fungus Colletotrichum sp. J Nat Prod 74:79–81.
- Want EJ, Smith CA, Brandon TR, et al. (2006). Solvent dependent metabolite distribution, clustering, and protein extraction for serum profiling with mass spectrometry. Anal Chem 78:743–52.
- Winder CL, Dunn WB, Schuler S, et al. (2008). Global metabolic profiling of Escherichia coli cultures: an evaluation of methods for quenching and extraction of intracellular metabolites. Anal Chem 80:2939–48.