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Original Article

Etiology of microglial nodules in brains of patients with acquired immunodeficiency syndrome

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Pages 46-50 | Received 30 Apr 1999, Accepted 31 Aug 1999, Published online: 10 Jul 2009

References

  • Anders K H, Guerra W F, Tomiyasu U, Verity M A, Vinters H V. The neuropathology of AIDS. UCLA experience and review. Am J Pathol 1986; 124: 537–558
  • Bell J E, Donaldson T K, Lowrie S, McKenzie C A, Elton R A, Chiswick A, Brettle R P, Ironside J W, Simmonds P. Influence of risk group and zidovudine therapy on the development of HIV encephalitis and cognitive impairment in AIDS patients. AIDS 1996; 10: 493–499
  • Budka H. Multinucleated giant cells in brain: a hallmark of acquired immunodeficiency syndrome (AIDS). Acta Neuropathol (Berl) 1986; 69: 253–258
  • Budka H, Costanzi G, Cristina S, Lechi A, Parravicini C, Trabattoni R, Vago L. Brain pathology induced by infection with the human immunodeficiency virus (HIV). A histological, immunocytochemical and electron microscopical study of 100 autopsy cases. Acta Neuropathol (Berl) 1987; 75: 185–198
  • Esiri M, Kennedy P. General pathological features of virus diseases of the central nervous system. Given‐field's Neuropathology5th eds, H J Adams, L W Duchen. Edward Arnold Press, Great Britain 1982; 341–352
  • Kato T, Hirano A, Llena J F, Dembtizer H M. Neuropathology of acquired immunodeficiency syndrome (AIDS) in 53 autopsy cases with particular emphasis on microglial nodules and multinucleated giant cells. Acta Neuropathol (Berl) 1987; 73: 287–294
  • Kure K, Llena J F, Lyman W D. Human immunodeficiency virus‐1 infection of the nervous system: an autopsy study of 268 adult, pediatric and fetal brains. Hum Pathol 1991; 22: 700–710
  • Lang W, Miklossy J, Deruaz J P, Pizzolato G P, Probst A, Schaffner T, Gessaga E, Kleihues P. Neuropathology of acquired immunodeficiency syndrome (AIDS): a report of 135 consecutive autopsy cases from Switzerland. Acta Neuropathol (Berl) 1989; 77: 379–390
  • Lanjewar D N, Jain P P, Shetty C R. Profile of central nervous system pathology in patients with AIDS: an autopsy study from India. AIDS 1998; 12: 309–313
  • Masliah E, Achim C L, Ge N, DeTeresa R, Terry R, Wiley C A. Spectrum of human immunodeficiency virus‐associated neocortical damage. Ann Neurol 1992; 32: 321–329
  • Morgello S, Cho E S, Nielsen S, Devinsky O, Petito C K. Cytomegalovirus encephalitis in patients with acquired immunodeficiency syndrome. An autopsy study of 30 cases and a review of literature. Hum Pathol 1987; 18: 289–297
  • Nielsen S L, Petito C K, Urmacher C D, Posner J B. Subacute encephalitis in acquired immunodeficiency syndrome: a postmortem study. Am J Clin Pathol 1984; 14: 403–418
  • Patsouris E, Kretzshmar H A, Stavrou D, Meharaein P. Cellular composition and distribution of gliomesenehymal nodules in the CNS of AIDS patients. Clinical Neuropathology 1993; 12: 130–137
  • Pelito C K, Cho E S, Lemann W, Navia B A S, Price R W. Neuropathology of acquired immunodeficiency syndrome (AIDS): an autopsy review. J Neuropathol Kxp Neurol 1980; 6: 639–646
  • Rhodes R H. Histopathological features in the central nervous system of 400 acquired immunodeficiency cases: implications of rates of occurrence. Hum Pathol 1993; 24: 1189–1198
  • Sharer L R, Kapila R. Neuropathology observations in acquired immunodeficiency syndrome (AIDS). Acta Neuropathol (Berl) 1985; 66: 188–198
  • Snider W D, Simpson D M, Nielsen S. Neurological complications of acquired immunodeficiency syndrome: analysis of 50 patients. Ann Neurol 1983; 14: 403–418
  • Vago L, Nebuloni M, Sala E, Cinque P, Bonetto S, Isella A, Ottoni L, Crociati A, Costanzi G. Coinfection of the central nervous system by cytomegalovirus and herpes simplex virus type 1 or 2 in AIDS patients: autopsy study on 82 cases by immunohistochemistry and polymerase chain reaction. Acta Neuropathol (Berl) 1990; 92: 404–408
  • Vago L, Barberis M, Gori A, Scarpellini P, Sala E, Nebuloni M, Bonetto S, Cannone M, Marchetti G, Franzetti F, Costanzi G. Nested PCR to M. tuberculosis IS6110 sequence on formalin‐fixed, paraffin‐embedded tissues with granulomatous disease for rapid diagnosis of tuberculosis. Am J Clin Pathol 1998; 109: 411–415
  • Vinters H V, Kwok M K, Ho H W, Anders K M, Tomiyasn U, Wolfson W L, Robert F. Cytomegalovirus in the nervous system of patients with the acquired immunodeficiency syndrome. Brain 1989; 112: 245–208
  • Wiley C A, Achim C. Human immunodeficiency virus encephalitis is the pathological correlate of dementia in acquired immunodeficiency syndrome. Ann Neurol 1995; 36: 673–676
  • Yau W L, Or S H, Ngai H K. A 'free floating' technique for reprocessing paraffin sections for electron microscopy. Med Lab Sciences 1985; 42: 20–29

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