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Original Article

Simian immunodeficiency virus mac251 infection of astrocytes

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Pages 173-186 | Received 28 Sep 1999, Accepted 25 Oct 1999, Published online: 10 Jul 2009

References

  • Adamson D C, Dawson T M, Zink M C, Clements J E, Dawson V L. Neurovirulent simian immunodeficiency virus infection induces neuronal, endothelial, and glial apoptosis. Mol Med 1996; 2: 417–428
  • Axthelm M K, Shiigi S M. Nonhuman primate models for acquired immunodeficiency syndrome. J Med Primatol 1990; 19: 163–165
  • Bachelerie F, Alcami J, Hazan U, Israel N, Goud B, Arenzana-Seisdedos F, Virelizier J L. Constitutive expression of human immunodeficiency virus (HIV) nef protein in human astrocytes does not influence basal or induced HTV long terminal repeat activity. J Virol 1990; 64: 3059–3062
  • Bagasra O, Lavi E, Bobroski L, Khalili K, Pestaner J P, Tawadros R, Pomerantz R J. Cellular reservoirs of HIV-1 in the central nervous system of infected individuals: Identification by the combination of in situ polymerase chain reaction and immunohisto-chemistry. AIDS 1996; 10: 573–585
  • Bailey M S, Shippley M T. Astrocyte subtypes in the rat olfactory bulb: Morphological heterogeneity and differential laminar distribution. J Comp Neurol 1993; 328: 501–526
  • Bayon-Auboyer M H, Boussin F D, Le Grand R, Dormont D. Evolution of the VI and V2 domains of the HIV-2 env gene in healthy but persistantly infected macaques. AIDS 1996; 10: 229–230
  • Bencheikh M, Bentsman G, Sarkissian N, Canki M, Volsky D J. Replication of different clones of human immunodeficiency virus type 1 in primary fetal human astrocytes: enhancement of viral gene expression by Nef. J Neurovirol 1999; 5: 115–124
  • Benveniste E N. Cytokines: influence on glial cell gene expression and function. Neuroimmunoendocrinology, J E Blalock, Basel 1992; Vol. 52: 106–153
  • Benveniste E N. Cytokine circuits in brain. Implications for AIDS dementia complex. HIV, AIDS, and the brain, R W Price, S W Perry. Raven Press, New York 1994; Vol. 72: 71–88
  • Brack-Werner R. Astrocytes: HIV cellular reservoirs and important participants in neuropathogenesis. AIDS 1999; 13: 1–22
  • Brack-Werner R, Erfle V, Ranki A. Significance of restricted HIV expression for HIV neuropathogenesis: still an unresolved issue. AIDS 1997; 11: 251–252
  • Brack-Werner R, Kleinschmidt A, Ludvigsen A, Mellert W, Neumann M, Herrmann R, Khim M CL, Burny A, Muller-Lantzsch N, Stavrou D, Erfle V. Infection of human brain cells by HIV-1: restricted virus production in chronically infected human glial cell lines. AIDS 1992; 6: 273–285
  • Brengel-Pesce K, Innocenti-Francillard P, Morand P, Chanzy B, Seigneurin J M. Transient infection of astrocytes with HIV-1 primary isolates derived from patients with and without AIDS dementia complex. J Neurovirol 1997; 3: 449–454
  • Brinkmann R, Schwinn A, Muller J, Stahl-Hennig C, Coulibaly C, Hunsmann G, Czub S, Rethwilm A, Dorries R, Ter Meulen V. In vitro and in vivo infection of rhesus monkey microglial cells by simian immunodeficiency virus. Virology 1993; 195: 561–568
  • Canki M, Potash M J, Bentsman G, Chao W, Flynn T, Heinemann M, Gelbard H, Volsky D J. Isolation and long-term culture of primary ocular human immunodeficiency virus type 1 isolates in primary astrocytes. J Neurovirol 1997; 3: 10–15
  • Chakrabarti L, Baptiste V, Khatissian E, Cumont M C, Aubertin A M, Montagnier L, Hurtrel B. Limited viral spread and rapid immune response in lymph nodes of macaques inoculated with attenuated simian immunodeficiency virus. Virology 1995; 213: 535–548
  • Cheng-Mayer C, Rutka J T, Rosenblum M L, Mc Hugh T, Stites D P, Levy J A. The human immunodeficiency virus can productively infect cultured human glial cells. Proc Natl Acad Sci USA 1987; 84: 3526–3530
  • Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987; 162: 156–159
  • Chowers M Y, Spina C A, Kwoh T J, Fitch N J, Richman D D, Guatelli J C. Optimal infectivity in vitro of human immunodeficiency virus type 1 requires an intact nef gene. J Virol 1994; 68: 2906–2914
  • Christofinis G, Papadaki L, Sattentau Q, Ferns R B, Tedder R. HTV replicates in cultured human brain cells. AIDS 1987; 1: 229–234
  • Clements J E, Anderson M G, Zink M C, Joag S V, Narayan O. The SIV model of AIDS encephalopathy. Role of neurotropic viruses in diseases. HIV, Aids, and the brain, R W Price, S W Perry. Raven Press, New York 1994; Vol. 72: 147–159
  • Clerici M, Sarin A, Coffman R L, Wynn T A, Blatt S P, Hendrix C W, Wolf S F, Shearer G M, Henkart P A. Typel/type2 cytokine modulation of T-cell programmed death as a model for human immunodeficiency virus pathogenesis. Proc Natl Acad Sci USA 1994; 91: 11811–11815
  • Croitoru J, Guillemin G J, Boussin F D, Lebel-Binay S, Le Grand R, Dormont D. Chemokines and chemo-kine receptors expression patterns in adult simian astrocyte cultures. J Neurovirol 1998; 4: 346
  • Desrosiers R C. The simian immunodeficiency viruses. Annu Rev Immunol 1990; 8: 557–578
  • Eddelston M, Mucke L. Molecular profile of reactive astrocytes-implications for their role in neurologic disease. Neuroscience 1993; 54: 15–36
  • Epstein L G, Gendelman H E. Human immunodeficiency virus type 1 infection of the nervous system: pathogenetic mechanisms. Ann Neurol 1993; 33: 429–436
  • Fiala M, Rhodes R H, Shapshak P, Nagano I, Martinezmaza O, Diagne A, Baldwin G, Graves M. Regulation of HIV-1 infection in astrocytes: Expression of Nef TNF-alpha and IL-6 is enhanced in coculture of astrocytes with macrophages. J Neurovirol 1996; 2: 158–166
  • Folks T M, Justement J, Kinter A, Dinarello C A, Fauci A S. Cytokine-induced expression of HIV-1 in a chronically infected promonocyte cell line. Science 1987; 238: 800–802
  • Fox H S, Gold L H, Henriksen S J, Bloom F E. Simian immunodeficiency virus: a model for neuroAIDS. Neurobiol Dis 1997; 4: 265–274
  • Gorry P R, Purcell D, Howard J, Mc Phee D. Restricted HIV-1 infection of human astrocytes: potential role of nef in the regulation of virus replication. J Neurovirol 1998; 4: 377–386
  • Gorry P R, Howard J L, Churchill M J, Anderson J L, Cunningham A, Adrian D, Mc Phee D A, Purcell D F. Diminished production of human immunodeficiency virus type 1 in astrocytes results from inefficient translation of gag, env, and nef mRNAs despite efficient expression of Tat and Rev. J Virol 1999; 73: 352–361
  • Gray F, Chimelli L, Mohr M, Clavelou P, Scaravilli F, Poirier J. Fulminating multiple sclerosis-like leukoencephalopathy revealing human immunodeficiency virus infection. Neurology 1991; 41: 105–109
  • Gray F, Scaravilli F, Evarll I, Chretien F, An S, Boche D, Adlebiassette H, Wingertsmann L, Durigon M, Hurtrel B, Chiodi F, Bell J, Lantos P. Neuropathology of early HTV-1 infection. Brain Pathol 1996; 6: 1–15
  • Guillemin G, Boussin F D, Legrand R, Croitoru J, Coffigny H, Dormont D. Granulocyte macrophage colony stimulating factor stimulates in vitro proliferation of astrocytes derived from simian mature brains. Glia 1996; 16: 71–80
  • Guillemin G, Boussin F D, Croitoru J, Franck-Duchenne M, Le Grand R, Lazarini F, Dormont D. Obtention and characterization of primary astrocyte and microglial cultures from adult monkey brains. J Neurosci Res 1997; 49: 576–591
  • Gyorkey F, Melnick J L, Gyorkey P. Human immunodeficiency virus in brain biopsies of patients with ADDS and progressive encephalopathy. J Infect Dis 1987; 155: 870–876
  • Hao H N, Lyman W D. HTV infection of fetal human astrocytes: the potential role of a receptor-mediated endocytic pathway. Brain Res 1999; 823: 24–32
  • Harouse J M, Bhat S, Spitalnik S L, Laughin M, Stefano K, Silberberg D H, Gonzales-Scarano F. Inhibition of entry of HTV-1 in neural cell lines by antibodies against galactosyl ceramide. Science 1991a; 253: 320–323
  • Harouse J M, Gonzalez-Scarano F. Infection of SK-N-MC cells, a CD4-negative neuroblastoma cell line, with primary human immunodeficiency virus type 1 isolates. J Virol 1996; 70: 7290–7294
  • Harouse J M, Laughlin M A, Pletcher C, Friedman H M, Gonzalez-Scarano F. Entry of human immunodeficiency virus-1 into glial cells proceeds via an alternate, efficient pathway. J Leukoc Biol 1991b; 49: 605–609
  • He J, Chen Y, Farzan M, Choe H, Ohagen A, Gartner S, Busciglio J, Yang X, Hofmann W, Newman W, Mackay C R, Sodroski J, Gabuzda D. CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia. Nature 1997; 385: 645–649
  • Klein R S, Williams K C, Alvarez-Hernandez X, Westmoreland S, Force T, Lackner A A, Luster A D. Chemokine receptor expression and signaling in macaque and human fetal neurons and astrocytes: implications for neuropathogenesis of AIDS. J Immunol 1999; 163: 1636–1646
  • Kleinschmidt A, Neumann M, Moller C, Erfle V, Brackwemer R. Restricted expression of HIV1 in human astrocytes: Molecular basis for viral persistence in the CNS. Res Virology 1994; 145: 147–153
  • Koedel U, Kohleisen B, Sporer B, Lahrtz F, Ovod V, Fontana A, Erfle V, Pflster H W. HIV Type 1 Nef protein is a viral factor for leukocyte recruitment into the central nervous system. J of Immunol 1999; 163: 1237–1245
  • Koenig S, Gendelman H E, Orenstein J M, Dal Canto M C, Pezeshkpour G H, Yungbluth M, Janotta F, Aksamit A, Martin M A, Fauci A S. Detection of ADDS virus in macrophages in brain tissue from AIDS patients with encephalopathy. Science 1986; 233: 1089–1093
  • Kohleisen B, Neumann M, Herrmann R, Brack-Werner R, Krohn K JE, Ovod V, Ranki A, Erfle V. Cellular localization of Nef expressed in persistently HTV-1-infected low-producer astrocytes. AIDS 1992; 6: 1427–1436
  • Kure K, Llena J F, Lyman W D, Soeiro R, Weidenheim K M, Hirano A, Dickson D W. Human immunodeficiency virus-1 infection of the nervous system: an autopsy study of 268 adult, pediatric, and fetal brains. Hum Pathol 1991; 22: 700–710
  • Kure K, Lyman W D, Weidenheim K M, Dickson D W. Cellular localization of an HTV-1 antigen in subacute AIDS encephalitis using an improved double-labeling immunohistochemical method. Am J Pathol 1990; 138: 1085–1092
  • Lackner A A, Smith M O, Munn R J, Martfeld D J, Gardner M B, Marx P A, Dandekar S. Localization of simian immunodeficiency virus in the central nervous system of rhesus monkeys. Am J Pathol 1991; 139: 609–621
  • Lairmore M D, Post A A, Goldsmith C S, Folks T M. Cytokine enhancement of simian immunodeficiency virus (SIV/mac) from a chronically infected cloned T-cell line (HuT-78). Arch Virol 1991; 121: 43–53
  • Le Grand R, Nadal M, Cheret A, Roques P, Vaslin B, Matheux F, Theodora F, Gras G, Gauthier L, Aubertin A M, et al. Infection of macaques after vaginal exposure to a primary isolate of SIVmac251. AIDS 1995; 9: 308–309
  • Ma M H, Geiger J D, Nath A. Characterization of a novel binding site for the human immunodeficiency virus type 1 envelope protein gpl20 on human fetal astrocytes. J Virol 1994; 68: 6824–6828
  • Matsuda S, Akagawa K, Honda M, Yokota Y, Takebe Y, Takemori T. Suppression of HIV replication in human monocyte-derived macrophages induced by granulocyte/macrophage colony-stimulating factor. AIDS Res Human Retrovir 1995; 11: 1031–1038
  • Mc Carthy M, He J, Wood C. HTV-1 strain-associated variability in infection of primary neuroglia. J Neurovirol 1998; 4: 80–89
  • Michaels J, Price R W, Rosenblum M K. Microglia in the giant cell encephalitis of acquired immune deficiency syndrome: proliferation, infection and fusion. Acta Neuropathol (Berl) 1988; 76: 373–379
  • Nath A, Hartloper V, Furer M, Fowke K R. Infection of human fetal astrocytes with HTV-1: viral tropism and the role of cell to cell contact in viral transmission. J Neuropathol Exp Neurol 1995; 54: 320–330
  • Nath A, Power C, Geiger J D. Interactions of the human immunodeficiency virus with astrocytes. HIV infection in CD4-cells, J Fantini, J-M Sabatier. AE Leiden,Escom Sci Publ BV, Netherlands 1996; Vol. 5: 30–42, PO Box 214, 2300
  • Navia B A, Cho E S, Petito C K, Price R W. The AIDS dementia complex: II. Neuropathology. Ann Neurol 1986b; 19: 525–536
  • Navia B A, Jordan B D, Price R W. The AIDS dementia complex: I. Clinical features. Ann Neurol 1986a; 19: 517–524
  • Navia B A, Price R W. The acquired immunodeficiency syndrome dementia complex as the presenting or sole manifestation of human immunodeficiency virus infection. Arch Neurol 1987; 44: 65–69
  • Neumann M, Felber B K, Kleinschmidt A, Froese B, Erfle V, Pavlakis G N, Brack-Werner R. Restriction of human immunodeficiency virus type 1 production in a human astrocytoma cell line is associated with a cellular block in Rev function. J Virol 1995; 69: 2159–2167
  • Nuovo G J, Gallery F, Macconnell P, Braun A. In Situ Detection of Polymerase Chain Reaction-Amplified HTV-1 Nucleic Acids and Tumor Necrosis Factor-alpha RNA in the Central Nervous System. Am J Pathol 1994; 144: 659–666
  • Oh J W, Schwiebert L M, Benveniste E N. Cytokine regulation of CC and CXC chemokine expression by human astrocytes. J Neurovirol 1999; 5: 82–94
  • Perno C F, Yarchoan R, Cooney D A, Hartman N R, Webbs D S, Hao Z, Mitsuya H, Johns D G, Broder S. Replication of human immunodeficiency virus in monocytes. Granulocyte/macrophage colony-stimulating factor (GM-CSF) potentiates viral production yet enhances the antiviral effect mediated by 3′-azido-2′3′-dideoxythymidine (AZT) and other dideoxynucleo-side. J Exp Med 1989; 169: 933–951
  • Petito C K, Roberts B. Evidence of apoptotic cell death in HTV encephalitis. Am J Pathol 1995; 146: 1121–1130
  • Price R W, Brew B, Sidtis J, Rosenblum M, Scheck A C, Cleary P. The brain in AIDS: central nervous system HTV-1 infection and AIDS dementia complex. Science 1988; 239: 586–591
  • Prochiantz A, Mallat M. Astrocyte diversity. Annals NY Academy of Sciences. 1988; 52–64
  • Ranki A, Nyberg M, Ovod V, Haltia M, Elovaara I, Raininko R, Haapasalo H, Krohn K. Abundant expression of HTV Nef and Rev proteins in brain astrocytes in vivo is associated with dementia. AIDS 1995; 9: 1001–1008
  • Rausch D M, Murray E A, Eiden L E. The STV-infected rhesus monkey model for HTV-associated dementia and implications for neruological diseases. J Leukoc Biol 1999; 65: 466–474
  • Richard A, Robichaud G, Lapointe R, Bourgoin S, Darveau A, Poulin L. Interference of HTV-1 nef in the sphingomyelin transduction pathway activated by tumor necrosis factor-a in human glial cells. AIDS 1997; 11: F1–F7
  • Ringler D J, Hunt R D, Desrosiers R C, Daniel M D, Chalifoux L V, King N W. Simian immunodeficiency virus induced meningoencephalitis: natural history and retrospective study. Ann Neurol 1988; 23(Supp)S101–S107
  • Romero I A, Teixeira A, Strosberg A D, Cazaubon S, Couraud P O. The HTV-1 nef protein inhibits extracellular signal-regulated kinase-dependent DNA synthesis in a human astrocytic cell line. J Neurochem 1998; 70: 778–785
  • Saas P, Walker P R, Hahne M, Quiquerez A L, Schnuriger V, Perrin G, French L, Van Meir E G, De Tibolet N, Tschopp J, Dietrich P Y. Fas ligand expression by astrocytoma in vivo: maintaining immune privilege in die brain?. J Clin Invest 1997; 99: 1173–1178
  • Sabri F, Tresoldi E, Di Stefano M, Polo S, Monaco M C, Verani A, Fiore J R, Lusso P, Major E, Chiodi F, Scarlatti G. First annual Gordon conference on Neurovirolgy, New London NHUSA, 1999
  • Saito Y, Sharer L R, Epstein L G, Michaels J, Mintz M, Louder M, Golding K, Cvetkovich T A, Blumberg B M. Overexpression of nef as a marker for restricted HIV-1 infection of astrocytes in postmortem pediatric central nervous tissues. Neurology 1994; 44: 474–480
  • Sasseville V G, Lackner A A. Neuropathogenesis of simian immunodeficiency virus infection in macaque monkeys. J Neurovirol 1997; 3: 1–9
  • Sharer L R. Neuropathology and pathogenesis of SIV infection of the central nervous system. HIV, AIDS, and the brain, R W Price, S W Perry. Raven Press, New York 1994; 133–147
  • Sharer L R, Baskin G B, Cho E-S, Murphey-Corb M, Blumberg B M, Epstein L G. Comparison of simian immunodeficiency virus and human immunodeficiency virus encephalitis in the immature host. Ann Neurol 1988; 23(Suppl)S108–S112
  • Sharer L R, Saito Y, Da Cunha A, Ung P, Gelbard H A, Epstein L G, Blumberg B M. In situ amplification and detection of HIV-1 DNA in fixed pediatric AIDS brain tissue. Human Pathol 1996; 27: 614–617
  • Staler M H, Eskin T A, Benn S, Angerer R C, Angerer L M. Human T-cell mymphotropic virus type in infection of the central nervous system. A preliminary in situ analysis. JAMA 1986; 256: 2360–2364
  • Swingler S, Easton A, Morris A. Cytoskine augmentation of HTV-1 LTR-driven gene expression in neural cells. Aids Res Hum Retroviruses 1992; 8: 487–493
  • Swingler S, Morris A, Easton A. Tumour necrosis factor alpha and interleukin-1 beta induce specific subunits of NF kappa B to bind the HTV-1 enhancer: Characterisation of transcription factors controlling human immunodeficiency virus type 1 gene expression in neural cells. Biochem Biophys Res Commun 1994; 203: 623–630
  • Thiele D L, Kurosaka M, Lipsky P E. Phenotype of the accessory cell necessary for mitogen-stimulated T and B cell responses in human peripheral blood: delineation by its sensitivity to the lysosomotropic agent, L-Leucine methyl ester. J Immunol 1983; 131: 2282–2290
  • Tornatore C, Chandra R, Berger J R, Major E O. HIV-1 infection of subcortical astrocytes in the pediatric central nervous system. Neurology 1994a; 44: 481–487
  • Tornatore C, Meyers K, Atwood W, Conant K, Major E. Temporal patterns of human immunodeficiency virus type 1 transcripts in human fetal astrocytes. J Virol 1994b; 68: 93–102
  • Tornatore C, Nath A, Amemiya K, Major E O. Persistent human immunodeficiency virus type 1 infection in human fetal glial cells reactivated by T-cell factor(s) or by the cytokines tumor necrosis factor alpha and interleukin-1 beta. J Virol 1991; 65: 6094–6100
  • Tyor W R, Glass J D, Griffin J W, Becker P S, Mc Arthur J C, Bezman L, Griffing D E. Cytokine expression in the brain during the acquired immunodeficiency syndrome. Ann Neurol 1992; 31: 349–360
  • Van Empel J, Ludwig E, Neumann M, Erfle V. Brack-Werner Analysis of RNA binding and oligo-merization activities of the HTV-1 Rev protein in human astrocytes. Cold Spring Harbour meeting. 1999, 357, abstract
  • Vazeux R, Brousse N, Jarry A, Henin D, Marche C, Vedrenne C, Mikol J, Wolff M, Michon C, Rozenbaum W. AIDS subacute encephalitis. Identification of HIV-infected cells. Am J Pathol 1987; 126: 403–410
  • Vitkovic L, Stover E, Koslow S H. Animal models recapitulate aspects of HTV/CNS disease. AIDS Res Hum Retroviruses 1995; 11: 753–759
  • Wakrim L, Le Grand R, Vaslin B, Chéret A, Matheux F, Theodoro F, Roques P, Nicol-Jourdan-Jourdan I, Dormont D. Superinfection of HTV-2-prein-fected macaques after rectal exposure to a primary isolate of STVmac251. Virology 1996; 221: 260–270
  • Walsh D G, Horvath C J, Hansen M A, Mac Key J J, Sehgal P K, Daniel M D, Desrosiers R C, Ringler D J. Cytokine influence on simian immunodeficiency virus replication within primary macrophages. TNF-alpha, but not GMCSF, enhances viral replication on a per-cell basis. Am J Pathol 1991; 139: 877–887
  • Wiley C A, Schrier R D, Denaro F J, Nelson J A, Lampert P W, Oldstone M BA. Cellular localization of human immunodeficiency virus infection within the brains of acquired immune dificiency syndrome patients. Proc Natl Acad Sci USA 1986; 83: 7089–7093
  • Wilkin G P, Levi M. Cerebellar astrocytes. Development, morphology, and regional specialization of astrocytes, S Fedoroff, E Vernadakis. Academic Press, Orlando 1986; Vol. 1: 245–268
  • Wilkin G P, Marriott D R, Cholewinski A J. Astrocyte heterogeneity. TINS 1990; 13: 43–46
  • Zink M C, Spelman J P, Robinson R B, Clements J E. STV infection of macaques-modeling the progression to AIDS dementia. J Neurovirol 1998; 4: 249–259

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