5
Views
1
CrossRef citations to date
0
Altmetric
Original Article

Analysis of human endothelial cells and cortical neurons for susceptibility to HIV-1 infection and co-receptor expression

, &
Pages 519-528 | Received 09 Feb 2000, Accepted 09 Jun 2000, Published online: 10 Jul 2009

References

  • Ades E W, Comans T W, Nicholson J KA, Browning S W. Lack of evidence that human immunodeficiency virus can infect human endothelial cells in vitro. J Acquir Immune Defic Syndr 1993; 6: 104–105
  • Aggoun-Zouaoui D, Charriaut-Marlangue C, Rivers S, Jorquera I, Ben-Ari Y, Represa A. The HIV-1 envelope protein gp120 induces neuronal apoptosis in hippocampal slices. NeuroReport 1996; 7: 433–436
  • An S F, Scaravilli F. Early HIV-1 infection of the central nervous system. Arch Anat Cytol Path 1997; 45: 94–105
  • An S F, Groves M, Giometto B, Beckett A A, Scaravilli F. Detection and localisation of HIV-1 DNA and RNA in fixed adult AIDS brain by polymerase chain reaction/in situ hybridisation technique. Acta Neuropathol 1999; 98: 481–487
  • Anderson M G, Sharma D P, Joag S V, Narayan O, Clements J E. Analysis of envelope changes acquired by SIV-mac239 during neuroadaption of rhesus macaques. Virology 1993; 195: 616–626
  • Benton P A, Timanus D K, Shearer M H, White G L, Lee D R, Kennedy R C. Analysis of nonhuman primate peripheral blood mononuclear cells for susceptibility to HIV-1 infection and HIV co-receptor expression. Dev Comp Immunol 1999; 23: 97–105
  • Berger O, Gan X, Gujuluva C, Bums A R, Sulor G, Stins M, Way D, Witte M, Weinand M, Said J, Kim K S, Taub D, Graves M C, Fiala M. CXC and CC chemokine receptors on coronary and brain endothelial. Mol Med 1999; 5: 795–805
  • Brenneman D E, McCune S K, Mervis R F, Hill J M. gp-120 as an etiologic agent for neuroAIDS: Neurotoxicity and model systems. Adv Neuroimmunol 1994; 4: 157–165
  • Brew B J. The pathogenesis of the neurological complications of HIV-1 infection. Genitourin Med 1993; 69: 333–340
  • Deng H, Liu R, Ellmeier W, Choe S, Unutmaz D, Burkhart M, Marzio P D, Marmon S, Sutton R E, Hill C M, Davis C B, Peiper S C, Schall T J, Littman D R, Landau N R. Identification of a major co-receptor for primary isolates of HIV-1. Nature 1996; 381: 661–666
  • Dragic T, Litwin V, Allaway G P, Martin S R, Huang Y, Nagashima K A, Cayanan C, Maddon P J, Koup R A, Moore J P, Paxton W A. HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR5. Nature 1996; 381: 667–673
  • Edinger A L, Mankowski J L, Doranz B J, Margulies B J, Lee B, Rucker J, Sharron M, Hoffman T L, Berson J F, Zink C, Hirsch V M, Clements J E, Doms R W. CD4-independent, CCR5-dependent infection of brain capillary endothelial cells by a neurovirulent simian immunodeficiency virus strain. Proc Natl Acad Sci USA 1997; 94: 14742–14747
  • Endres M J, Clapham P R, Marsh M, Ahuja M, Turner J D, McKnight A, Thomas J F, Stoebnau-Haggarty B, Choe S, Vance P J, Wells T NC, Power C A, Sutterwala S S, Doms R W, Landau N R, Hoxie J A. CD4-independent infection by HIV-2 is mediated by fusin/CXCR4. Cell 1996; 87: 745–756
  • Ensoli F, Cafaro A, Fiorelli V, Vannelli B, Ensoli B, Thiele C J. HIV-1 infection of primary human neuroblasts. Virology 1995; 210: 221–225
  • Feil C, Augustin H G. Endothelial cells differentially express functional CXC-chemokine receptor-4 (CXCR-4/Fusin) under the control of autocrine activity and exogeneous cytokines. Biochem Biophys Res Commun 1998; 247: 38–45
  • Fiala M, Looney D J, Stins M, Way D D, Zhang L, Gan X, Chiappelli F, Schweitzer E S, Shapshak P, Weinand M, Graves M C, Witte W, Kim K S. TNF-alpha opens a paracellular route for HIC-1 invasion across the blood-brain barrier. Mol Med 1997; 3: 553–564
  • Giangaspero F, Scanabissi E, Baldacci M C, Betts C M. Masive neuronal destruction in human immunodeficiency virus encephalitis: A clinico-pathological study of a pediatric case. Acta Neuropathol 1989; 78: 662–665
  • Gilles P N, Lathey J L, Spector S A. Replication of macrophage-tropic and T-cell tropic strains of human immunodeficiency virus type is augmented by macrophage-endothelial cell contact. J Virol 1995; 69: 2133–2139
  • Gray F, Haug H, Chimelli L, Geny C, Gaston A, Scaravilli F, Budka H. Prominent cortical atrophy with neuronal loss as correlate of human immunodeficiency virus encephalopathy. Acta Neuropathol 1991; 82: 229–233
  • Harouse J M, Kunsch C, Hartle H T, Laughlin M A, Hoxie J A, Wigdahl B, Gonzalez-Scavano F. CD4-independent infection of human neural cells by human immunodeficiency virus type 1. J Virol 1989; 86: 2527–2533
  • Hesselgesser J, Halks-Miller M, DelVecchio V, Peiper S C, Hoxie J, Kolson D L, Taub D, Horuk R. CD4-independent association between HIV-1 gp120 and CXCR4: functional chemokine receptors are expressed in human neurons. Curr Biol 1997; 7: 112–121
  • Kanmogne G D, Grammas P, Kennedy R C. Cytotoxicity of HIV-1 gp160 peptides on neurons and brain endothelial cells. The FASEB J 1999; 13: A645, 10
  • Ketzler S, Weis S, Huag H, Budka H. Loss of neurons in the frontal cortex in AIDS brains. Acta Neuropathol 1990; 80: 92–94
  • Klein R S, Williams K C, Alvarez-Hernandez X, Westmoreland S, Force T, Lackner A A, Luster A D. Chemokine receptor expression and signaling in macaques and human fetal neurons and astrocytes: implication for the neuropathogenesis of AIDS. J Immunol 1999; 163: 1636–1646
  • Koenig S, Gendelman H E, Orenstein J M, dal Canto M C, Pezeshkpour G H, Yungbluth M, Janotta F, Aksamit A, Martin M A, Fauci A S. Detection of AIDS virus in macrophages in brain tissue from AIDS patients with encephalopathy. Science 1986; 233: 1089–1093
  • Lafon M E, Steffan A M, Gendrault J L, Klein-Soyer C, Gloeckler-Tondre L, Roger C, Kirn A. Interaction of human immunodeficiency virus with human microvascular endothelial cells in vitro. AIDS Res Hum Retroviruses 1992; 8: 1567–1570
  • Landau N L, Littman D R. Packaging system for rapid production of murine leukemia virus vectors with variable tropism. J Virol 1992; 66: 5110–5113
  • Lavi E, Stizki J M, Ulrich A M, Zhang W, Fu L, Wang Q, O'Connor M, Hoxie J A, Gonzalez-Scavano F. CXCR4 (Fusin), a co-receptor for the type 1 HIV-1, is expressed in the human brain in a variety of cell types, including microglia and neurons. Am J Pathol 1997; 151: 1035–1042
  • Li X L, Moudgil T, Vinters H V, Ho D D. CD4-independent, productive infection of a neuronal cell line by human immunodeficiency virus type 1. J Virol 1990; 64: 1383–1387
  • MacArthur J C. Neurologic manifestations of AIDS. Medicine 1987; 66: 407–437
  • Mankowski J L, Spelman J P, Ressetar H G, Strandberg J D, Laterra J, Carter D L, Clements J E, Zinc M C. Neurovirulent simian immunodeficiency virus replicates productively in endothelial cells of the central nervous system in vivo and in vitro. J Virol 1994; 68: 8202–8208
  • Meucci O, Miller R J. gp120-induced neurotoxicity in hippocampal pyramidal neuron cultures: Protective action of TGF-beta1. J Neurosci 1996; 16: 4080–4088
  • Mizrachi Y, Rodriguez I, Sweetnam P M, Rubinstein A, Volsky D J. HIV type 1 infection of human cortical neuronal cells: enhancement by select neuronal growth factors. AIDS Res Hum Retrovir 1994; 10: 1593–1596
  • Moses A V, Bloom P E, Pauza D, Nelson J A. Human immunodeficiency virus infection of a human brain capillary endothelial cells occurs via a CD4/galactosylceramide-independent mechanism. Proc Natl Acad Sci USA 1993; 90: 10474–10478
  • Moses V, Nelson J A. HIV infection of human brain capillary endothelial cells-Implication for AIDS dementia. Adv Neuroimmunol 1994; 4: 239–247
  • Navia B A, Jordan B D, Price R W. The AIDS dementia complex I. Clinical features. Ann Neurol 1986; 19: 517–524
  • Nottet H SLM, Persidsky Y, Sasseville V G, Nukuna A N, Bock P, Zhai Q H, Sharer L R, McComb R D, Swindells S, Soderland C, Gendelman H E. Mechanisms for the transendothelial migration of HIV-1-infected monocytes into brain. J Immunol 1996; 156: 1284–1295
  • Perno C F, Yarchoan R. Culture of HIV in Monocytes and Macrophages. Current Protocols in Immunology, J E Coligan, A M Kruisbeek, D H Margules, E M Shevach, W Strobe. National Institute of Health. 1993; 12.4.1–12.4.11
  • Poland S D, Rice G PA, Dekaban G A. HIV-1 infection of human brain-derived microvascular endothelial cells in vitro. J AIDS and Human Retrovirology 1995; 8: 437–445
  • Price R W, Brew B, Sidtis J, Rosenblum M, Scheck A C, Cleary P. The brain in AIDS: Central nervous system HIV-1 infection and AIDS dementia complex. Science 1988; 239: 586–592
  • Pulliam L, Clarke J A, McGuire D, McGrath M S. Investigation of HIV-infected macrophage neurotoxin production from patients with AIDS dementia. Adv Neuroimmunol 1994; 4: 195–198
  • Pyra H, Boni J, Schupbach J. Ultrasensitive retrovirus detection by a reverse transcriptase assay based on product enhancement. Proc Natl Acad Sci USA 1994; 91: 1544–1548
  • Ray P E, Liu X H, Henry D, Dye L, III, Xu L, Orenstein J M, Schuztbank T E. Infection of human primary renal epithelial cells with HIV-1 from children with HIV-associated nephropathy. Kidney Int 1998; 53: 1217–1229
  • Rottman J B, Ganley K P, Williams K, Wu L, Mackay C R, Ringler D J. Cellular localization of the chemokine receptor CCR5. Correlation to cellular targets of HIV-1 infection. Am J Pathol 1997; 151: 1341–1351
  • Sanders V J, Pittman C A, White M G, Wang G, Wiley C A, Achim C L. Chemokines and receptors in HIV encephalitis. AIDS 1998; 12: 1021–1026
  • Sharpless N, Gilbert D, Vandercam B, Zhou J M, Verdin E, Ronnett G, Friedman E, Dubois-Dalcq M. The restricted nature of HIV-1 tropism for cultured neural cells. Virology 1992; 191: 813–825
  • Shearer M H, Bright R K, Kennedy R C. Molecular characterization of immunoglobulin variable regions from murine monoclonal antibodies specific for simian virus 40 large tumor antigen. Scan J Immunol 1994; 40: 415–422
  • Simmons G, Wilkinson D, Reeves J D, Dittmar M T, Beddows S, Weber J, Carnegie G, Desselberger U, Gray P W, Weiss R A, Clapham P R. Primary, syncytium-inducing human immunodeficiency virus type 1 isolates are dual-tropic and most can use either Lestr of CCR5 as co-receptors for virus entry. J Virol 1996; 70: 8355–8360
  • Sinclair E, Gray F, Ciardi A, Scaravilli F. Immunohistochemical changes and PCR detection of HIV provirus DNA in brains of asymptomatic HIV-positive patients. J Neuropathol Exp Neurol 1994; 53: 43–50
  • Steffan A M, Lafon M E, Gendrault J L, Schweitzer C, Royer C, Jaeck D, Arnaud J P, Schmitt M P, Aubertin A M, Kirn A. Primary culture of endothelial cells from the human liver sinusoid are permissive for human immunodeficiency virus type 1. Proc Natl Acad Sci USA 1992; 89: 1582–1586
  • Strelow L I, Watry D D, Fox H S, Nelson J A. Efficient infection of brain microvascular endothelial cells by an in vivo-selected neuroinvasive SIV mac variant. J Neurovirol 1998; 4: 269–280
  • Takahashi K, Wesselingh S L, Griffin D E, McArthur J C, Johnson R T, Glass J D. Localization of HIV-1 in human brain using polymerase chain reaction: In situ hybridization and immunocytochemistry. Ann Neurol 1996; 39: 705–711
  • Tateno M, Gonzalez-Scavano F, Levy J A. Human immunodeficiency virus can infect CD4-negative human fibroblastoid cells. Proc Natl Acad Sci USA 1989; 86: 4287–4290
  • Truckenmiller M E, Kulaga H, Coggiano M, Wyatt R, Snyder S H, Sweetnam P M. Human cortical neuronal cell line: a model for HIV-1 infection in an immature neuronal system. AIDS Res Hum Retrovir 1993; 9: 445–453
  • Vallat A V, Girolami U D, He J, Mhashilkar A, Marasco W, Shi B, Gray F, Bell J, Keohane C, Smith T W, Gabuzda D. Localization of HIV-1 coreceptors CCR5 and CXCR4 in the brain of children with AIDS. Am J Pathol 1998; 152: 167–178
  • Wesselingh S L, Powers C, Glass J D, Tyor W R, McArthur J C, Farber J M, Griffin J W, Griffin D E. Intracerebral cytokine messenger RNA expression in acquired immunodeficiency syndrome dementia. Ann Neurol 1993; 33: 576–582
  • Wiley C A, Schrier R D, Nelson J A, Lampert P W, Oldstone M BA. Cellular localization of human immunodeficiency virus infection within the brains of acquired immune deficiency syndrome patients. Proc Natl Acad Sci USA 1986; 83: 7089–7093

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.