Latent simian varicella virus reactivates in monkeys treated with tacrolimus with or without exposure to irradiation

References

• Ashburn CV, Gray WL (2002). Expression of the simian varicella virus glycoprotein L and H. Arch Virol 147:335–348.
   PubMed Web of Science ®Google Scholar
• Caproni M, Torchia D, Antiga E, Volpi W, Bianco ED, Fabbri P (2006). The effects of tacrolimus ointment on regulatory T lymphocytes in atopic dermatitis. J Clin Immunol 26:370–375.
   PubMed Web of Science ®Google Scholar
• Cohrs RJ, Gilden DH (2007). Prevalence and abundance of latently transcribed varicella-zoster virus genes in human ganglia. J Virol 81:2950–2956.
   PubMed Web of Science ®Google Scholar
• Fehr T, Bossart W, Wahl C, Binswanger U (2002). Disseminated varicella infection in adult renal allograft recipients: four cases and a review of the literature. Transplantation 73:608–611.
   PubMed Web of Science ®Google Scholar
• Gourishankar S, McDermid JC, Jhangri GS, Preiksaitis JK (2004). Herpes zoster infection following solid organ transplantation: incidence, risk factors and outcomes in the current immunosuppressive era. Am J Transplant 4:108–115.
   PubMed Web of Science ®Google Scholar
• Han SK, Song JY, Yun YS, Yi SY (2002). Gamma irradiation-reduced IFN-gamma expression, STAT1 signals, and cell-mediated immunity. J Biochem Mol Biol 35:583–589.
   PubMedGoogle Scholar
• Hukkanen RR, Gillen M, Grant R, Liggitt HD, Kiem HP, Kelley ST (2009). Simian varicella virus in pigtailed macaques (Macaca nemestrina): clinical, pathologic, and virologic features. Comp Med 59:482–487.
   PubMed Web of Science ®Google Scholar
• Kennedy PGE, Grinfeld E, Gow JW (1998). Latent varicella-zoster virus is located predominantly in neurons in human trigeminal ganglia. Proc Natl Acad Sci U S A 95:4658–4662.
   PubMed Web of Science ®Google Scholar
• Kennedy PGE, Grinfeld E, Traina-Dorge V, Gilden DH, Mahalingam R (2004). Neuronal localization of simian varicella virus DNA in ganglia of naturally infected African green monkeys. Virus Genes 28:273–276.
   PubMed Web of Science ®Google Scholar
• Koc Y, Miller KB, Schenkein DP, Griffith J, Akhtar M, Jardin DJ, Snydman DR (2000). Varicella zoster virus infections following allogeneic bone marrow transplantation: frequency, risk factors, and clinical outcome. Biol Blood Marrow Transplant 6:44–49.
   PubMed Web of Science ®Google Scholar
• Kolappaswamy K, Mahalingam R, Traina-Dorge V, Shipley ST, Gilden DH, Kleinschmidt-DeMasters BK, McLeod CG Jr, Hungerford LL, DeTolla LJ (2007). Disseminated simian varicella virus infection in an irradiated rhesus macaque (Macaca mulatta). J Virol 81:411–415.
   PubMed Web of Science ®Google Scholar
• Kronenberg A, Bossart W, Wuthrich RP, Cao C, Lautenschlager S, Wiegand ND, Mullhaupt B, Noll G, Mueller NJ, Speck RF (2005). Retrospective analysis of varicella zoster virus (VZV) copy DNA numbers in plasma of immunocompetent patients with herpes zoster, of immunocompromised patients with disseminated VZV disease, and of asymptomatic solid organ transplant recipients. Transpl Infect Dis 7:116–121.
   PubMed Web of Science ®Google Scholar
• LaGuardia JJ, Cohrs RJ, Gilden DH (1999). Prevalence of varicella-zoster virus DNA in dissociated human trigeminal ganglion neurons and nonneuronal cells. J Virol 73:8571–8577.
   PubMed Web of Science ®Google Scholar
• Levin MJ, Cai GY, Manchak MD, Pizer LI (2003). Varicella-zoster virus DNA in cells isolated from human trigeminal ganglia. J Virol 77:6979–6987.
   PubMed Web of Science ®Google Scholar
• Ljungman P, Lönnqvist B, Gahrton G, Gahrton G, Ringdén O, Sundqvist VA, Wahren B (1986). Clinical and subclinical reactivations of varicella-zoster virus in immunocompromised patients. J Infect Dis 153:840–847.
   PubMed Web of Science ®Google Scholar
• Mahalingam R, Clarke P, Wellish M, Dueland AN, Soike KF, Gilden DH, Cohrs R (1992). Prevalence and distribution of latent simian varicella virus DNA in monkey ganglia. Virology 188:193–197.
   PubMed Web of Science ®Google Scholar
• Mahalingam R (2010). Simian varicella virus pathogenesis. In: Current Topics in Microbiology and Immunology, Vol 342. Varicella-zoster virus, Abendroth A (eds). Springer Heidelberg. pp 309–321.
   Google Scholar
• Mahalingam R, Traina-Dorge V, Wellish M, Lorino R, Sanford R, Ribka EP, Alleman SJ, Brazeau E, Gilden DH (2007). Simian varicella virus reactivation in cynomolgus monkeys. Virology 368:50–59.
   PubMed Web of Science ®Google Scholar
• Mahalingam R, Traina-Dorge V, Wellish M, Smith J, Gilden DH (2002). Naturally acquired simian varicella virus infection in African green monkeys. J Virol 76:8548–8550.
   PubMed Web of Science ®Google Scholar
• Mahalingam R, Wellish M, Cohrs R, Debrus S, Piette J, Rentier B, Gilden DH (1996). Expression of protein encoded by varicella-zoster virus open reading frame 63 in latently infected human ganglionic neurons. Proc Natl Acad Sci U S A 93:2122–2124.
   PubMed Web of Science ®Google Scholar
• Mahalingam R, Wellish M, Soike K, White T, Kleinschmidt-DeMasters BK, Gilden DH (2001). Simian varicella virus infects ganglia before rash in experimentally infected monkeys. Virology 279:339–342.
   PubMed Web of Science ®Google Scholar
• Mandal BK (1987). Herpes zoster and the immunocompromised. J Infect 14:1–5.
   PubMed Web of Science ®Google Scholar
• Mehta SK, Cohrs RJ, Forghani B, Zerbe G, Gilden DH, Pierson DL (2004). Stress-induced subclinical reactivation of varicella zoster virus in astronauts. J Med Virol 72:174–179.
   PubMed Web of Science ®Google Scholar
• Messaoudi I, Barron A, Wellish M, Engelmann F, Legasse A, Planer S, Gilden D, Nikolich-Zugich J, Mahalingam R (2009). Simian varicella virus infection of rhesus macaques recapitulates essential features of varicella zoster virus infection in humans. PLoS Pathog 5:e1000657.
   PubMed Web of Science ®Google Scholar
• Mori T, Aisa Y, Nakazato T, Yamazaki R, Shimizu T, Mihara A, Yamane A, Ikeda Y, Okamoto A (2007). Tacrolimus and methotrexate for the prophylaxis of graft-versus-host disease after unrelated donor cord blood transplantation for adult patients with hematologic malignancies. Transplant Proc 39:1615–1619.
   PubMed Web of Science ®Google Scholar
• Rifkind D (1966). The activation of varicella-zoster virus infections by immunosuppressive therapy. J Lab Clin Med 68:463–474.
   PubMed Web of Science ®Google Scholar
• Schoeb TR, Eberle R, Black DH, Parker RF, Cartner SC (2008). Diagnostic exercise: papulovesicular dermatitis in rhesus macaques (Macaca mulatta). Vet Pathol 45:592–594.
   PubMed Web of Science ®Google Scholar
• Soike KF, Huang JL, Zhang JY, Bohm R, Hitchcock MJ, Martin JC (1991). Evaluation of infrequent dosing regimens with (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]-cytosine (S-HPMPC) on simian varicella infection in monkeys. Antiviral Res 16:17–28.
   PubMed Web of Science ®Google Scholar
• Verjans GM, Hintzen RQ, van Dun JM, Poot A. Milikan JC, Laman JD, Langerak AW, Kinchington PR, Osterhaus AD (2007). Selective retention of herpes simplex virus-specific T cells in latently infected human trigeminal ganglia. Proc Natl Acad Sci U S A 104: 3496–3501.
   PubMed Web of Science ®Google Scholar
• White TM, Mahalingam R, Traina-Dorge V, Gilden DH (2002a). Persistence of simian varicella virus DNA in CD4(+) and CD8(+) blood mononuclear cells for years after intratracheal inoculation of African green monkeys. Virology 303:192–198.
   PubMed Web of Science ®Google Scholar
• White TM, Mahalingam R, Traina-Dorge V, Gilden DH (2002b). Simian varicella virus DNA is present and transcribed months after experimental infection of adult African green monkeys. J NeuroVirol 8:191–203.
   PubMed Web of Science ®Google Scholar