49
Views
2
CrossRef citations to date
0
Altmetric
Original Article

Neuropathogenicity of mouse hepatitis virus JHM isolates differing in hemagglutinin-esterase protein expression

, , , , , , , & show all
Pages 330-339 | Published online: 10 Jul 2009

References

  • Buchmeier, Lewicki, Talbot, Knobler. Murine hepatitis virus (strain JHM)-induced neurologic disease is modulated in vivo by monoclonal antibody. Virology 1984; 132: 261–270
  • Collins, Knobler, Powell, Buchmeier. Monoclonal antibodies to murine hepatitis virus -4 (strain JHM) define the viral glycoprotein responsible for attachment and cell-cell fusion. Virology 1982; 119: 358–371
  • Dalziel, Lampert, Talbot, Buchmeier. Site-specific alteration of murine hepatitis virus type-4 (MHV-4) peplomer glycoprotein E2 results in reduced neurovirulence. J Virol 1986; 59: 463–471
  • Deregt, Babiuk. Monoclonal antibodies to bovine coronavirus: Characteristics and topographical mapping of neutralizing epitopes on the E2 and E3 glycoproteins. Virology 1987; 161: 410–420
  • Fazakerley, Parker, Bloom, Buchmeier. The V5A13.1 envelope glycoprotein deletion mutant of mouse hepatitis virus type-4 is neuroattenuated by its reduced rate of spread in the central nervous system. Virology 1992; 187: 178–188
  • Fleming, Stohlman, Harmon, Lai MC, Frelinger, Weiner. Antigenic relationship of murine coronaviruses: Analysis using monoclonal antibodies to JHM [MHV-4] virus. Virology 1983; 131: 296–307
  • Fleming, Trousdale, El-Zaatari AK, Stohlman, Weiner. Pathogenicity of antigenic variants of murine coronavirus JHM selected with monoclonal antibodies. J Virol 1986; 58: 869–875
  • Fleming, Shubin, Sussman, Casteel, Stohlman. Monoclonal antibodies to the matrix (E1) glycoprotein of mouse hepatitis virus protect mice from encephalitis. Virology 1989; 168: 162–167
  • Fleming, Wang I, Trousdale, Hinton, Stohlman. Interaction of immune and central nervous systems: Contribution of anti-viral Thy 1+ cells to demyelination induced by coronavirus JHM. Reg Immunol 1993; 37–43
  • Gallagher, Parker, Buchmeier. Neutralization-resistant variants of a neurotropic coronavirus are generated by deletions within the amino-terminal half of the spike glycoprotein. J Virol 1990; 64: 731–741
  • Hirano, Fujiwara, Hino, Matsumoto. Replication and plaque formation of mouse hepatitis virus (MHV-2) in mouse cell line DBT culture. Arch Gesomte Virusforsch 1974; 44: 298–302
  • Knobler, Dubois-Dalcq, Haspel, Claysmith, Lampert, Oldstone BA. Selective localization of wild type and mutant mouse hepatitis virus (JHM strain) antigens i n CNS tissue by fluorescence, light and electron microscopy. J Neuroimmunol 1981; 81–92
  • Kubo, Yamada, Taguchi. Localization of neutralizing epitopes and the receptor-binding site within the amino-terminal 330 amino acids of the murine coronavirus spike protein. J Virol 1994; 68: 5403–5410
  • Lai MC, Brayton, Armen, Patton, Pugh, Stohlman. Mouse hepatitis virus A59: Messenger RNA structure and genetic localization of the sequence divergence from the hepatotropic strain MHV 3. J Virol 1981; 39: 823–834
  • Lampert, Sims, Kniazeff. Mechanism of demyelination in JHM virus encephalomyelitis: Electron microscope studies. Acta Neuropathol 1973; 24: 76–85
  • Lee J, Shieh K, Gorbalenya, Koonin, La Monica, Tuler, Bagdzyahdzhyan, Lai M-C. The complete sequence (22 kilobases) of murine coronavirus gene 1 encoding the putative proteases and RNA polymerase. Virology 1991; 180: 567–582
  • Leibowitz, Weiss, Paavola, Bond. Cell-free translation of murine coronavirus RNA. J Virol 1982; 43: 905–913
  • Leibowitz, Wilhelmsen, Bond. The virus specific intracellular RNA species of two murine coronaviruses: MHV-A59 and MHV-JHM. Virology 1981; 114: 39–51
  • Makino, Lai M-C. Evolution of the 5′-end of genomic RNA of murine coronaviruses during passages in vitro. Virology 1989; 169: 227–232
  • Makino, Taguchi, Hirano N., Fujiwara. Analysis of genomic and intracellular viral RNAs of small plaque mutants of mouse hepatitis virus, JHM strain. Virology 1984; 139: 138–151
  • Makino, Soe, Shieh K, Lai MC. Discontinuous transcription of coronavirus mRNAs generates a variable number of pentanucleotide repeats at the leader fusion site. J Virol 1988; 62: 3870–3873
  • McCarthy, de Vellis. Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissues. J Cell Biol 1980; 85: 890–902
  • Nakanaga, Yamanouchi, Fujiwara. Protective effect of monoclonal antibodies on lethal mouse hepatitis virus infection in mice. J Virol 1986; 59: 168–171
  • Pachuk, Bredenbeek, Zoltick, Spaan JM, Weiss. Molecular cloning of the gene encoding the putative polymerase of mouse hepatitis coronavirus strain A59. Virology 1989; 171: 141–148
  • Parker, Gallagher, Buchmeier. Sequence analysis reveals extensive polymorphism and evidence of deletions within the E2 glycoprotein gene of several strains of murine hepatitis virus. Virology 1989; 173: 664–673
  • Pfleiderer, Routledge, Herrler, Siddell. High level transient expression of the murine coronavirus haemagglutinin-esterase. J Gen Virol 1991; 72: 1309–1315
  • Shieh K, Lee J, Yokomori, La Monica, Makino, Lai MC. Identification of a new transcriptional initiation site and the corresponding functional gene 2b in the murine coronavirus RNA genome. J Virol 1989; 63: 3729–3736
  • Siddell. Coronavirus JHM: Coding assignments of subgenomic MRNAs. J Gen Virol 1983; 64: 113–125
  • Sorensen, Perry, Dales. In vivo and in vitro models of demyelinating diseases. III. JHM virus infection of rats. Arch Neurol 1980; 37: 478–484
  • Stohlman, Weiner. Chronic central nervous systems demyelination in mice after JHM virus infection. Neurology 1981; 31: 38–44
  • Stohlman, Baric, Nelson, Soe, Welter, Deans. Specific interaction between coronavirus leader RNA and nucleocapsid protein. J Virol 1988; 62: 4288–4295
  • Storz, Zhang, Rott. Comparison of hemagglutinating, receptor-destroying and acetylesterase activities of avirulent and virulent bovine coronavirus strains. Arch Viroll 1992; 125: 193–204
  • Sturman, Holmes, Behnke. Isolation of coronavirus envelope glycoproteins and interaction with the viral nucleocapsid. J Virol 1980; 33: 444–462
  • Sturman, Ricard, Holmes. Proteolytic cleavage of the E2 glycoprotein of murine coronavirus: Activation of cell fusing activity of virions by trypsin and separation of two different 90K cleavage fragments. J Virol 1985; 56: 904–911
  • Sundarraj, Schachner, Pfeiffer. Biochemically differentiated mouse glial lines carrying a nervous system specific cell surface antigen (NS-I). Proc Natl Acad Sci USA 1975; 72: 1927–1931
  • Taguchi, Massa, ter Meulen. Characteristization of a variant virus isolated from neural cell culture after infection of a mouse coronavirus JHMV. Virolog 1986; 155: 267–270
  • Vlasak, Luytjes, Lieder, Spaan, Palese. The E3 protein of bovine coronavirus is a receptor-destroying enzyme with acetyltransferase activity. J Virol 1988a; 62: 4686–4690
  • Vlasak, Lúytjes, Spaan JM, Palese. Human and bovine coronaviruses recognize sialic acid-containing receptors similar to those of influenza C viruses. Proc Natl Acad Sci USA 1988ab; 85: 4526–4529
  • Wang I, Stohlman, Fleming. Dernyelination induced by murine hepatitis virus JHM strain (MHV-4) is immunologically mediated. J Neuroimmunol 1990; 30: 31–44
  • Wang I, Fleming, Lai MC. Sequence analysis of the spike protein gene of murine coronavirus variants: Study of genetic sites affecting neuropathogenicity. Virology 1992; 186: 742–749
  • Wege, Winter, Meyermann. The peplomer protein E2 of coronavirus JHM as a determinant of neurovirulence: Definition of critical epitopes by variant analysis. J Gen Virol 1988; 69: 87–98
  • Weiner. Pathogenesis of demyelination induced by a mouse hepatitis virus (JHM virus). Arch Neuro 1997; 318: 298–30
  • Yokomori, La Monica, Makino, Shieh K, Lai MC. Biosynthesis, structure, and biological activities of envelope protein gp65 of murine coronavirus. Virology 1989; 173: 683–691
  • Yokomori, Banner, Lai MC. Heterogeneity of gene expression of hemagglutinin-esterase (HE) protein of murine coronavirus. Virology 1991; 183: 647–657
  • Yokomori, Baker, Stohlman, Lai MC. Hemagglutinin-esterase (HE)-specific monoclonal antibodies alter the neuropathogenicity of mouse hepatitis virus. J Virol 1992; 66: 2865–2874
  • Yu, Bi, Weiss, Leibowitz. Mouse hepatitis virus gene 5b protein is a new virion envelope protein. Virology 1994; 202: 1018–1023
  • Zhang, Liao L, Lai MC. Coronavirus leader RNA regulates and initiates subgenomic mRNA transcription, both in trans and in cis. J Virol 1994; 68: 4738–4746

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.