References
- Aiken J M, Williamson J L, Borchardt M, Marsh R F. Presence of mitochondrial D-loop DNA in scrapie-infected brain preparations enriched for prion protein. J Virol 1990; 64: 3265–3268
- Akowitz A, Manuelidis L. A novel cDNA/PCR strategy for efficient cloning of small amounts of undefined RNA. Gene 1989; 81: 295–306
- Akowitz A, Sklaviadis T, Manuelidis E E, Manuelidis L. Nuclease resistant polyadenylated RNAs of significant size are detected by PCR in highly purified Creutzfeldt-Jakob disease preparations. Microb Pathogenesis 1990; 9: 33–45
- Akowitz A, Sklaviadis T, Manuelidis L. Endogenous viral complexes with long RNA cosediment with the agent of Creutzfeldt-Jakob Disease. Nucleic Acids Res 1994; 22: 1101–1107
- Baldwin M A, Cohen F E, Prusiner S B. Prion protein isoforms, a convergence of biological and structural investigations. J Biol Chem 1995; 270: 1919–1920, 7-0
- Bessen R A, Kocisko D A, Raymond G J, Nandan S, Lansbury P T, Caughey B. Non-genetic propagation of strain-specific properties of scrapie prion protein. Nature 1995; 375: 698–700
- Bradley R. Third International symposium on transmissible subacute spongiform encephalopathies: prion diseases. March 18-20. Paris 1996, Abs #8
- Bruce M E, Dickinson A G. Biological evidence that scrapie has an independent genome. J Gen Virol 1987; 68: 79–89
- Bruce M E, McConnell I, Fraser H, Dickinson A G. The disease characteristics of different strains of scrapie in Sine congenic mouse lines: implications for the nature of the agent and host control of pathogenesis. J Gen Virol 1991; 72: 595–603
- Chirgwin J M, Przybyla A E, MacDonald R J, Rutter W J. Biochemistry 1979; 18: 5294–5299
- Collinge J, Palmer M S, Sidle K C, Hill A F, Gowland I, Meads J, Asante E, Bradley R, et al. Unaltered susceptibility to BSE in transgenic mice expression human prion protein. Nature 1995; 378: 779–783
- Gajdusek D C. Unconventional viruses and the origin and disappearance of kuru. Science 1977; 197: 943–960
- Hadlow W J. Scrapie and kuru. Lancet 1959; ii: 289–290
- Hope J. Mice and beef and brain diseases. Nature 1995; 378: 761–762
- Hsiao K, Groth D, Scott M, Yang S L, Serban H, Rapp D, Foster D, Torchia M, et al. Serial transmission in rodents of neurodegeneration from transgenic mice expressing mutant prion protein. Proc Natl Acad Sci (USA) 1994; 91: 9126–9130
- Hubank M, Schatz D G. Identifying differences in mRNA expression by representational difference analysis of cDNA. Nucleic Acids Res 1994; 22: 5640–5648
- Lisitsyn N, Lisitsyn N, Wigler M. Cloning the differences between two complex genomes. Science 1993; 259: 946–951
- Manuelidis E E, Manuelidis L. Clinical and morphological aspects of transmissible Creutzfeldt-Jakob Disease. Prog Neuropath 1979; 4: 1–26
- Manuelidis E E, Manuelidis L. Suggested links between different types of dementias: Creutzfeldt-Jakob disease, Alzheimer Disease, and retroviral CNS infections. Alzheimer Dis Assoc Disord 1989; 3: 100–109
- Manuelidis L. The dimensions of Creutzfeldt-Jakob Disease. Transfusion 1994; 34: 915–928
- Manuelidis L, Fritch W. Infectiviry and host responses in Creutzfeldt-Jakob Disease. Virology 1996; 215: 46–59
- Manuelidis L, Murdoch G, Manuelidis E E. Potential involvement of retroviral elements in human dementias. Ciba Found Symp 1988; 135: 117–134
- Manuelidis L, Sklaviadis T, Akowitz A, Fritch W. Viral particles are required for infection in neurodegenerative Creutzfeldt-Jakob disease. Proc. Natl Acad Sci (USA) 1995; 92: 5124–5128
- Manuelidis L, Sklaviadis T, Manuelidis E E. On the origin and significance of scrapie associated fibrils. Unconventional Virus Diseases of the Central Nervous System, L. A. Court, et al. Masson, Paris 1986; 221–230
- Ozel M, Xi Y-G, Baldauf E, Diringer H, Pocchiari M. Small virus-like structure in brains from cases of sporadic and familial Creutzfeldt-Jakob disease. Lancet 1994; 344: 923–924
- Prusiner S B. Molecular biology of prion diseases. Science 1991; 252: 1515–1522
- Prusiner S B, Baldwin M, Collinge J, DeArmond S J, Marsh R, Tateishi J, Weissmann C. Prions. Virus Taxonomy, F. A. Murphy, et al. Springer Verlag, Wien 1995; 498–503
- Riesner D, Kellings K, Post K, Wille H, Serban H, Groth D, Baldwin M A, Prusiner S B. Disruption of prion rods generates 10-nm spherical particles having high a-helical content and lacking scrapie infectivity. J Virol 1996; 70: 1714–1722
- Rohwer R G. The scrapie agent: ‘a virus by any other name’. Cur Topics Microbiol Immunol 1991; 172: 195–232
- Selvaggini C, DeGioia L, Cantu L, Ghibaudi E, Diomede L, Passerini F, Forloni G, Bugiani O, et al. Molecular characteristics of a protease-resistant, amyloidogenic and neurotoxic peptide homologous to residues 106-126 of the prion protein. Biochem Biophys Acta 1993; 194: 1380–1386
- Simons J N, Pilot-Matias T J, Leary T P, Dawson G J, Desai S M, Schlauder G G, Muerhoff A S, Erker J C, et al. Identification of two flavivirus-like genomes in the GB hepatitis agent. Proc Natl Acad Sci (USA) 1995; 92: 3401–3405
- Sklaviadis T, Akowitz A, Manuelidis E E, Manuelidis L. Nuclease treatment results in high specific purification of Creutzfeldt-Jakob disease infectivity with a density characteristic of nucleic acid-protein complexes. Arch Virol 1990; 112: 215–229
- Sklaviadis T, Akowitz A, Manuelidis E E, Manuelidis L. Nucleic acid binding proteins in highly purified Creutzfeldt-Jakob disease preparations. Proc Natl Acad Sci (USA) 1993; 90: 5713–5717
- Sklaviadis T, Dreyer R, Manuelidis L. Analysis of Creutzfeldt-Jakob disease infectious fractions by gel permeation chromatography and sedimentation field flow fractionation. Virus Res 1992; 26: 241–254
- Telling G C, Scott M, Mastrianni J, Gabizon R, Torchia M, Cohen F E, DeArmond S J, Prusiner S B. Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein. Cell 1995; 83: 79–90