Spl and related factors fail to interact with the NF-kB-proximal G/C box in the LTR of a replication competent, brain-derived strain of HIV-1 (YU-2)

Reference

• Ait-Khaled M., Mclaughlin J. E., Johnson M. A., Emery V. C. Distinct HIV-1 long terminal repeat quasispe-cies present in nervous tissues compared to that in lung, blood and lymphoid tissues of an AIDS patient. AIDS 1995; 9: 675–683
   PubMed Web of Science ®Google Scholar
• Apt D., Watts R. M., Suske G., Bernard H. U. High Spl/Sp3 ratios in epithelial cells during epithelial differentiation and cellular transformation correlate with the activation of the HPV-16 promoter. Virology 1996; 224: 281–291
   PubMed Web of Science ®Google Scholar
• Bagasra O., Lavi E., Bobroski L., Khalili K., Pestaner J. P., Tawadros R., Pomerantz R. J. Cellular reservoirs of HIV-1 in the central nervous system of infected individuals: identification by the combination of in situ polymerase chain reaction and immunohisto-chemistry. AIDS 1996; 10: 573–585
   PubMed Web of Science ®Google Scholar
• Brack-Werner R., Kleinschmidt A., Ludvigsen A., Mellert W., Neumann M., Herrmann R., Khim M. C., Burny A., Muller-Lantzsch N., Stavrou D., Erfle V. Infection of human brain cells by HIV-1.restricted virus production in chronically infected human glial cell lines. AIDS 1992; 6: 273–285
   PubMed Web of Science ®Google Scholar
• Bradford M. M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976; 72: 248–254
   PubMed Web of Science ®Google Scholar
• Birnbaum M. J., Van Wijnen A. J., Odgren P. R., Last T. J., Suske G., Stein G. S., Stein J. L. Spl trans-activation of cell cycle regulated promoters is selectively repressed by Sp3. Biochemistry 1995; 34: 16503–16508
   Google Scholar
• Cullen B. R. Regulation of human immunodeficiency virus replication. Annu Rev Micro 1991; 45: 219–250
   PubMed Web of Science ®Google Scholar
• Desai-Yajnik V., Samuels H. H. The NF-kappa B and Spl motifs of the human immunodeficiency virus type 1 long terminal repeat function as novel thyroid hormone response elements. Mol Cell Biol 1993; 13: 5057–5069
   PubMedGoogle Scholar
• Dewhurst S., Bresser J., Stevenson M., Sakai K., Evinger-Hodges M. J., Volsky D. J. Susceptibility of human glial cells to infection with human immunodeficiency virus (HIV). FEBS Lett 1987; 213: 138–143
   Google Scholar
• Dignam J. D., Lebovitz R. M., Roeder R. G. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 1983; 11: 1475–1489
   PubMed Web of Science ®Google Scholar
• Garner M. M., Revzin A. A gel electrophoresis method for quantifying the binding of proteins to specific DNA regions: application to components of the Escherichia coli lactose operon regulatory system. Nuc Acids Res 1981; 9: 3047–3060
   PubMed Web of Science ®Google Scholar
• Goodenow M. M., Huet T., Saurin W., Kwok S., Sninsky J., Wain-Hobson S. HIV-1 isolates are rapidly evolving quasispecies: evidence for viral mixtures and preferred nucleotide substitutions. Acquir Immune Defic Syndr Hum Retrovirol 1989; 2: 344–352
   PubMedGoogle Scholar
• Hagen G., Muller S., Beato M., Suske G. Cloning by recognition site screening of two novel GT box binding proteins: a family of Spl related genes. Nucleic Acids Res 1992; 20: 5519–5525
   PubMedGoogle Scholar
• Harrich D., Garcia J., Wu F., Mitsuyasu R., Gonazalez J., Gaynor R. Role of Spl-binding domains in in vivo transcriptional regulation of the human immunodeficiency virus type 1 long terminal repeat. Virol 1989; 63: 2585–2591
   Google Scholar
• Jones K. A., Kadonaga J. T., Luciw P. A., Tjian R. Activation of the AIDS retrovirus promoter by the cellular transcription factor, Spl. Science 1986; 232: 755–759
   PubMed Web of Science ®Google Scholar
• Jones K. A., Peterlin B. M. Control of RNA initiation and elongation at the HIV-1 promoter. Annu Rev Biochem 1994; 63: 717–743
   PubMed Web of Science ®Google Scholar
• Katz R. A., Skalka A. M. Generation of diversity in retroviruses. Annu Rev Genet 1990; 24: 409–445
   PubMedGoogle Scholar
• Kennett S. B., Udvadia A. J., Horitz J. M. Sp3 encodes multiple proteins that differ in their capacity to stimulate or repress transcription. Nucleic Acids Res 1997; 25: 3110–3117
   PubMed Web of Science ®Google Scholar
• Kim S. J., Onwuta U. S., Lee Y. I., Li R., Botchman M. R., Robbins P. D. The retinoblastoma gene product regulates Spl-mediated transcription. Mol Cell Biol 1992; 12: 2455–2463
   PubMed Web of Science ®Google Scholar
• Kim J. Y., Gonzalez-Scarano F., Zeichner S. L., Alwine J. C. Replication of type 1 human immunodeficiency viruses containing linker substitution mutations in the -201 to –130 region of the long terminal repeat. Virol 1993; 67: 1658–1662
   Google Scholar
• Kingman S. M., Kingman A. J. The regulation of human immunodeficiency virus type-1 gene expression. Eur J Biochem 1996; 240: 491–507
   Google Scholar
• Kingsley C., Winoto A. Cloning of GT box-binding proteins: a novel Spl multigene family regulating T-cell receptor gene expression. Mol Cell Biol 1992; 12: 4251–4261
   PubMedGoogle Scholar
• Koenig S., Gendelman H. E., Orenstein J. M., Dal Canto M. C., Pezeshkpour G. H., Yungbluth M., Janotta F., Aksamit A., Martin M. A., Fauci A. S. Detection of AIDS virus in macrophages in brain tissue from AIDS patients with encephalopathy. Science 1986; 233: 1089–1093
   PubMed Web of Science ®Google Scholar
• Koken S. E., Van Wamel J. L., Goudsmit J., Berkhout B., Geelen J. L. Natural variants of the HIV-1 long terminal repeat: analysis of promoters with duplicated DNA regulatory motifs. Virology 1992; 191: 968–972
   PubMedGoogle Scholar
• Kriwacki R. W., Schultz S. C., Steitz T. A., Caradonna J. P. Sequence-specific recognition of DNA by zinc-finger peptides derived from the transcription factor Spl. Proc Natl Acad Sci USA 1992; 89: 9759–9763
   PubMed Web of Science ®Google Scholar
• Li Y., Kappes J. C., Conway J. A., Price R. W., Shaw- G. M., Hahn B. H. Molecular characterization of human immunodeficiency virus type 1 cloned directly from uncultured human brain tissue: identification of replication-competent and -defective viral genomes. Virol 1991; 65: 3973–3985
   Google Scholar
• Li Y., Mak G., Franza B. R., Jr. In vitro study of functional involvement of Spl, NF-kappa B/Rel, and API in phorbol 12-myristate 13-acetate-mediated HIV-1 long terminal repeat activation. Biol Chem 1994; 269: 30616–30619
   Google Scholar
• Majello B., De Luca P., Hagen G., Suske G., Lania L. Different members of the Spl multigene family exert opposite transcriptional regulation of the long terminal repeat of HIV-1. Nucleic Acids Res 1994; 22: 4914–4921
   PubMedGoogle Scholar
• Michael N. L., D'Arcy L., Ehrenberg P. K., Rodfield R. R. Naturally occurring genotypes of the human immunodeficiency virus type 1 long terminal repeat display a wide range of basal and tat-induced transcriptional activities. Virol 1994; 68: 3163–3174
   Google Scholar
• Moses A. V., Ibanez C., Gaynor R., Ghazal P., Nelson J. A. Differential role of long terminal repeat control elements for the regulation of basal and Tat-mediated transcription of the human immunodeficiency virus in stimulated and unstimulated primary human macrophages. Virol 1994; 68: 298–307
   Google Scholar
• Myers G., Foley B., Mellors J. W., Korber B., Wain-Hobson S. Human retroviruses and AIDS 1996. A compilation and analysis of nucleic and amino acid sequences, K-T Jeang. Los Alamos National Laboratory, Los Alamos, NM 1996
   Google Scholar
• Nuovo G. J., Gallery F., Macconnell P., Braun A. In situ detection of PCR-amplified HIV-1 nucleic acids and tumor necrosis factor alpha RNA in the central nervous system. Am J Pathol 1994; 144: 659–666
   PubMedGoogle Scholar
• Perkins N. D., Edwards N. L., Duckett C. S., Agranoff A. B., Schmid R. M., Nabel G. J. A cooperative interaction between NF-kappa B and Spl is required for HIV-1 enhancer activation. EMBO J 1993; 12: 3551–3558
   PubMed Web of Science ®Google Scholar
• Price R. W. Understanding the AIDS Dementia Complex (ADC): The challenge of HIV and its effects on the central nervous system. HIV, AIDS and the Brain, RW Price, SW Perry, III. Raven Press, New York 1994; 1–45
   Google Scholar
• Ross E. K., Buckler-White A. J., Rabson A. B., Englund G., Martin M. A. Contribution of NF-kappa B and Spl binding motifs to the replicative capacity of human immunodeficiency virus type1: distinct patterns of viral growth are determined by T-cell types. Virol 1991; 65: 4350–4358
   Google Scholar
• Sune C., Garcia-Blanco M. A. Spl transcription factor is required for in vitro basal and Tat-activated transcription from the human immunodeficiency virus type 1 long terminal repeat. Virol 1995; 69: 6572–6576
   Google Scholar
• Tornatore C., Nath A., Amemiya K., Major E. O. Persistent human immunodeficiency virus type 1 infection in human fetal glial cells reactivated by T-cell factor(s) or by the cytokines tumor necrosis factor alpha and interleukin-1 beta. Virol 1991; 65: 6094–6100
   Google Scholar
• Tornatore C., Chandra R., Berger J. R., Major E. O. HIV-1 infection of subcortical astrocytes in the pediatric central nervous system. Neurology 1994; 44: 481–487
   PubMed Web of Science ®Google Scholar
• Wen S. C., Ku D. H., De Luca A., Claudio P. P., Giordano A., Calabretta B. ets-2 regulates cdc2 kinase activity in mammalian cells: coordinated expression of cdc2 and cyclin A. Exp Cell Res 1995; 217: 8–14
   PubMedGoogle Scholar
• Wiley C. A., Schrier R. D., Nelson J. A., Lampert P. W., Oldstone M.B.A. Cellular localization of human immunodeficiency virus infection within the brains of acquired immune deficiency syndrome patients. Proc Natl Acad Sci USA 1986; 83: 7089–7093
   PubMed Web of Science ®Google Scholar
• Wingender E., Kel A. E., Kel O. V., Karas H., Heinemeyer T., Dietze P., Knuppel R., Romaschenko A. G., Kolchanov N. A. TRANSFAC, TRRD and COMPEL: towards a federated database system on transcriptional regulation. Nucleic Acids Res 1997; 25: 265–268
   PubMed Web of Science ®Google Scholar
• Zeichner S. L., Kim J. Y., Alwine J. C. Linker-scanning mutational analysis of the transcriptional activity of the human immunodeficiency virus type 1 long terminal repeat. Virol 1991; 65: 2436–2444
   Google Scholar