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Original Article

Replication of different clones of human immunodeficiency virus type 1 in primary fetal human astroyctes: enhancement of viral gene expression by Nef

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Pages 115-124 | Received 04 Aug 1997, Accepted 24 Aug 1998, Published online: 10 Jul 2009

References

  • Adachi A, Gendelman H, Koenig S, Folks T, Willey R, Rabson A, Martin M. Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone. J Virol 1986; 59: 284–291
  • Current Protocols in Molecular Biology, F Ausubel, R Brent, R Kingston, D Moore, J Seidman, J Smith, K Struhl. John Wiley & Sons. 1989
  • Bagasra O, Khalili K, Seshamma T, Taylor J P, Pomerantz R J. TAR-independent replication of human immunodeficiency virus type 1 in glial cells. J Virol 1992; 66: 7522–7528
  • Benos D J, Hahn B H, Bubien J K, Ghosh S K, Mashbum N A, Chaikin M A, Shaw G M, Benveniste E N. Envelope glycoprotein gpl20 of human immunodeficiency virus type 1 alters ion transport in astrocytes: implications for AIDS dementia complex. Proc Natl Acad Sci 1994; 91: 494–498
  • Canki M, Potash M J, Bentsman G, Chao W, Flynn T, Heinemann M, Gelbard H, Volsky D J. Isolation and long-term culture of primary ocular human immunodeficiency virus type 1 isolates in primary astrocytes. J Neuro Virol 1997; 3: 10–15
  • Cheng-Mayer C, Rutka J, Rosenblum M, McHugh T, Stites D, Levy J. Human immunodeficiency virus can productively infect cultured human glial cells. Proc Natl Acad Sci USA 1987; 84: 3526–3530
  • Chesebro B, Buller R, Portis J, Wehrly K. Failure of human immunodeficiency entry and infection in CD4-positive human brain and skin cells. J Virol 1990; 64: 215–221
  • Chiodi F, Fuerstenberg S, Gidlund M, Asjo B, Fenyo E M. Infection of brain derived cells with the HIV. J Virol 1987; 61: 1244–1247
  • Chowdhury I H, Chao W, Potash M J, Sova P, Gendelman H E, Volsky D J. vif-negative human immunodeficiency virus type 1 persistently replicates in primary macrophages, producing attenuated progeny virus. J Virol 1996; 70: 5336–5345
  • Clapham P R, Weber J N, Whitby D, McIntosh K, Dalgleish A G, Maddon P J, Deen K C, Sweet R W, Weiss R A. Soluble CD4 blocks the infectivity of diverse strains of HIV SIV for T cells and monocytes but not for brain and muscle cells. Nature 1989; 337: 368–370
  • Collman R, Balliet J W, Gregory S A, Friedman H, Kolson D L, Nathanson N, Srinivasan S. An infectious molecular clone of an unusual macrophage-tropic and highly cytopathic strain of human immunodeficiency virus type 1. J Virol 1992; 66: 7517–7521
  • Collins K L, Chen B K, Kalams S A, Walker B D, Baltimore D. HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes. Nature 1998; 391: 397–401
  • Connor R I, Chen B K, Choe S, Landau N R. Vpr is required for efficient replication of human immunodeficiency virus type 1 in mononuclear phagocytes. Virology 1995; 206: 935–944
  • Dewhurst S, Sakai K, Bresser J, Stevenson M, Eringer-Hodges M J, Volsky D J. Persistent productive infection of human glial cells by HIV and by infectious molecular clones of HIV. J Virol 1987; 61: 3774–3782
  • Gabuzda D H, Li H, Lawrence K, Vasir B S, Crawford K, Langhoff E. Essential role of vif in establishing productive HIV-1 infection in peripheral blood T lymphocytes and monocyte/macrophages. J Acq Imm Def Syn 1994; 7: 908–915
  • Gendelman H E, Orenstein Martin M, Gerrua G, Mitra R, Phipp s T, Wahl I, Lane C, Fauci A, Burke D, Skillman D, Meltzer M. Efficient isolation and propagation of human immunodeficiency virus on recombinant colony-stimulating factor-1 treated monocytes. J Exp Med 1988; 167: 1428–1441
  • Harouse J, Kunsch C, Hartle H, Laughlin M, Hoxie J, Wigdahl B, Gonzalez-Scarano F. CD4 independent infection of human neural cells by HIV-1. J Virol 1989; 63: 2527–2533
  • Hatch W C, Pousada E, Losev I, Rashbaum W K, Lyman W D. Neural cell targets of human immunodeficiency virus type 1 fetal organotypic cultures. AIDS Res & Hu Retrov 1994; 10: 1597–1607
  • He J, Chen Y, Farzan M, Choe H, Ohagen A, Gartner S, Buscigllo J, Yang X, Hofmann W, Newman W, Mackay C R, Sodroski J, Gabuzda D. CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia. Nature 1997a; 385: 645–649
  • He J, DeCastro C M, Vandenbark G R, Busciglio J, Gabuzda D. Astrocyte apoptosis induced by HIV-1 transactivation of the c-kit protooncogene. Proc Natl Acad Sci 1997b; 94: 3954–3959
  • Kunsch C, Wigdahl B. Transient expression of HIV-1 genome results in a nonproductive infection of human fetal dorsal root ganglia glial cells. Virology 1989; 171: 715–722
  • Li Y, Kapp es J, Conway J, Price R, Shaw G, Hahn B. Molecular characterization of human immunodeficiency virus type 1 cloned directly from uncultured brain tissue, identification of replication competent and defective viral genomes. J Virol 1991; 65: 3973–3985
  • Lipton S, Gendelman H. Dementia associated with the acquired immuno-deficiency syndrome. N Engl J Med 1995; 233: 934–940
  • Littman D R. Chemokine receptors: keys to AIDS pathogenesis?. Cell 1998; 93: 677–680
  • Mizrachi Y, Zeira M, Shahabuddin M, Li G, Sinangil F, Volsky D J. Efficient binding, fusion and entry of HIV-1 into CD4 negative neural cells: a mechanism for neuropathogenesis in AIDS. Bull Inst Pasteur 1991; 89: 81–96
  • Nath A, Hartloper V, Furer M, Fowke K R. Infection of human fetal astrocytes with HIV-1: viral tropism and the role of cell to cell contact in viral transmission. J Neuropath & Exp Neurol 1995; 54: 320–330
  • Neumann M, Felber B K, Kleinschmidt A, Froese B, Erfle V, Pavlakis G N, Brack-Werner D. Restriction of human immunodeficiency virus type 1 production in a human astrocytoma cell line is associated with a cellular block in Rev function. J Virol 1995; 69: 2159–2167
  • Nussbaum O, Broder C C, Berger E A. Fusogenic mechanisms of enveloped-virus glycoproteins analyzed by a novel recombinant vaccinia virus-based assay quantitating cell fusion-dependent reporter gene activation. J Virol 1994; 68: 5411–5422
  • Price R, Brew B, Sidtis J, Rosenblum M, Scheck A, Cleary P. The brain in AIDS: central nervous HIV-1 infection and AIDS dementia complex. Science 1988; 239: 586–591
  • Ranki A, Nyberg M, Ovod V, Haltia M, Elovara I, Raininko R, Haapasalo H, Krohn K. Abundant expression of HIV nef and rev proteins in brain astrocytes in vivo is associated with dementia. AIDS 1995; 9: 1001–1008
  • Saito Y, Sharer L, Epstein L, Michaels J, Mintz M, Louder M, Golding K, Cvetkovich T, Blumberg B. Overexpression of nef as a marker for restricted HIV-1 infection of astrocytes in postmortem pediatric central nervous system. Neurology 1994; 44: 474–481
  • Sakai K, Dewhurst S, Ma X, Volsky D J. Differences in cytopathogenicity and host cell range among infectious molecular clones of HIV-1 simultaneously isolated from an individual. J Virol 1988; 62: 4078–4085
  • Sakai K, Ma X, Gordienko I, Volsky D J. Recombinational analysis of a natural noncytopathic human immunodeficiency virus type 1 (HIV-1) isolate: Role of the vif gene in HIV-1 infection kinetics and cytopathicity. Virol 1991; 65: 5765–5773
  • Shahabuddin M, Volsky B, Kim H, Sakai K, Volsky D J. Regulated expression of human immunodeficiency virus type 1 in human glial cells: induction of dormant virus. Pathobiology 1992; 60: 195–205
  • Shahabuddin M, Bentsman G, Volsky B, Rodriguez I, Volsky D J. A mechanism of restricted human immunodeficiency virus type 1 expression in human glial cells. J Virol 1996; 70: 7992–8002
  • Sharer L R. Pathology of HIV-1 infection of the central nervous system. J Neuropathol Exp Neurol 1992; 51: 3–11
  • Shaw G, Hahn B, Arya S, Groopman J, Gallo R, Wong-Staal F. Molecular characterization of human T-cell leukemia lymphotropic virus type III in the acquired immune deficiency syndrome. Science 1984; 226: 1165–1171
  • Simm M, Shahabuddin M, Chao W, Allan J S, Volsky D J. Aberrant Gag protein composition of a human immunodeficiency virus type 1 vif mutant produced in primary lymphocytes. J Virol 1995; 69: 4582–4586
  • Sova P, Chao W, Volsky D J. The redox state of cysteines in human immunodeficiency virus type 1 Vif in infected cells and in virions. Biochemi & Bioph Res Comm 1997; 240: 257–260
  • Spire B, Sire J, Zachar V, Rev F, Barre-Sinoussi F, Galibert F, Hampe A, Chermann J C. Nucleotide sequence of HIV-1-NDK: a highly cytopathic strain of the human immunodeficiency virus. Gene 1989; 81: 275–284
  • Srinivasan A, Anand R, York D, Ranganathan P, Feorino P, Schochetman G, Curran J, Kalyanaraman V, Luciw P, Sanchez-Pesdador R. Molecular characterization of human immunodeficiency virus from Zaire: nucletotide sequence analysis identified conserved and variable domains in the envelope gene. Gene 1987; 52: 71–82
  • Srinivasan A, Dorsett D, York D, Bohan C, Anand R. HIV replication in human brain cells. Arch Virol 1988; 99: 135–141
  • Staler M H, Eskin T A, Steven B, Angerer R C, Angerer L M. Human T-cell lymphotropic virus type III infection of the central nervous system: A preliminary in situ analysis. JAMA 1996; 256: 2360–2364
  • Takahashi K, Wesselingh S L, Griffin D E, McArthur J C, Johnson R T, Glass J D. Localization of HIV-1 in human brain using polymerase chain reaction/in situ hybridization and immunocvtochemistry. Ann Neurol 1996; 39: 705–711
  • Tillman M, Krebs F C, Wessner R, Pomeroy S M, Goodenow M M, Wigdahl B. Neuroglial-specific factors and the regulation of retrovirus transcription. Adv In Neuroimmunol 1994; 4: 305–318
  • Tornatore C, Nath A, Amemiya K, Major E. Persistent HIV-1 infection in human fetal glial cells reactivated by T-cell factor(s) or by the cytokines tumor necrosis factor alpha and interleukin-a beta. J Virol 1991; 65: 6094–6100
  • Tornatore C, Chandra R, Berger J, Major E. HIV-1 infection of subcortical astrocytes in the pediatric central nervous system. Neurology 1994a; 44: 481–487
  • Tornatore C, Meyers K, Atwood W, Conant K, Major E. Temporal patterns of human immunodeficiency virus type 1 transcripts in human fetal astrocytes. J Virol 1994b; 68: 93–102
  • Tornatore C, Nath A, Amemiya K, Major E. Persistent HIV-1 infection in human fetal glial cells reactivated by T-cell factor(s) or by the cytokines tumor necrosis factor alpha and interleukin-a beta. J Virol 1991; 65: 6094–6100
  • Trono D. HIV accessory proteins: leading roles for the supp orting cast. Cell 1995; 82: 189–192
  • Volsky D J, Shahabuddin M, Mizrachi Y. The role of human immunodeficiency virus type 1 (HIV-1) in neurologic disorders of AIDS. Molecular Neurovirology, R P Roos. Humana Press Inc., Totowa, NJ 1992
  • Volsky B, Sakai K, Reddy M M, Volsky D J. A system for the high efficiency replication of HIV-1 in neural cells and its app lication to anti-viral evaluation. Virology 1992; 186: 303–308
  • von Schwedler U, Song J, Aiken C, Trono D. vif is crucial for human immunodeficiency virus type 1 proviral DNA synthesis in infected cells. J Virol 1993; 67: 4945–4955
  • Westervelt P, Gendelman H E, Ratner L. Identification of a determinant within the human immunodeficiency virus surface envelope glycoprotein critical for productive infection of primary monocytes. Proc Natl Acad Sci USA 1991; 88: 3097–3101

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