Lack of influence of rs4680 (COMT) and rs6276 (DRD2) on diagnosis and clinical outcomes in patients with major depression

References

• Abou Jamra R, Becker T, Georgi A, Feulner T, Schumacher J, Stromaier J, et al. 2008. Genetic variation of the FAT gene at 4q35 is associated with bipolar affective disorder. Mol Psychiatry 13: 277–284.
   Google Scholar
• Andrews JM, Ninan PT, Nemeroff CB. 1996. Venlafaxine: a novel antidepressant that has a dual mechanism of action. Depression 4: 48–56.
   PubMedGoogle Scholar
• Arias B, Serretti A, Lorenzi C, Gastó C, Catalán R, Fañanás L. 2006. Analysis of COMT gene (Val 158 Met polymorphism) in the clinical response to SSRIs in depressive patients of European origin. J Affect Disord 90:251–256.
   PubMed Web of Science ®Google Scholar
• Badner JA, Gershon ES. 2002. Meta-analysis of whole-genome linkage scans of bipolar disorder and schizophrenia. Mol Psychiatry 7: 405–411.
   PubMed Web of Science ®Google Scholar
• Baune BT, Hohoff C, Berger K, Neumann A, Mortensen S, Roehrs T, et al. 2008. Association of the COMT val158met variant with antidepressant treatment response in major depression. Neuropsychopharmacology 33:924–932.
   PubMed Web of Science ®Google Scholar
• Belmaker RH, Agam G. 2008. Major depressive disorder. N Engl J Med 358:55–68.
   PubMed Web of Science ®Google Scholar
• Carlborg O, Haley CS. 2004. Epistasis: too often neglected in complex trait studies?Nat Rev Genet 5:618–625.
   PubMed Web of Science ®Google Scholar
• Cohen J. 1988. Statistical power analysis for the behavioral sciences. Hillsdale, New Jersey: Lawrence Erlbaum Associates.
   Google Scholar
• Cusin C, Serretti A, Lattuada E, Lilli R, Lorenzi C, Smeraldi E. 2002. Association study of MAO-A, COMT, 5-HT2A, DRD2, and DRD4 polymorphisms with illness time course in mood disorders. Am J Med Genet 114:380–390.
   PubMed Web of Science ®Google Scholar
• Dechant KL, Clissold SP. 1991. Paroxetine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in depressive illness. Drugs 41:225–253.
   PubMed Web of Science ®Google Scholar
• Gvozdic K, Brandl EJ, Taylor DL, Müller DJ. 2012. Genetics and personalized medicine in antidepressant treatment. Curr Pharm Des 18:5853–5878.
   PubMed Web of Science ®Google Scholar
• Hamilton M. 1960. A rating scale for depression. J Neurol Neurosurg Psychiatry 23:56–62.
   PubMed Web of Science ®Google Scholar
• Hashimoto R, Okada T, Kato T, Kosuga A, Tatsumi M, Kamijima K, Kunugi H. 2005. The breakpoint cluster region gene on chromosome 22q11 is associated with bipolar disorder. Biol Psychiatry 57:1097–1102.
   PubMed Web of Science ®Google Scholar
• Illi A, Setala-Soikkeli E, Kampman O, Viikki M, Nuolivirta T, Poutanen O, et al. 2010. Catechol-O-methyltransferase val108/ 158met genotype, major depressive disorder and response to selective serotonin reuptake inhibitors in major depressive disorder. Psychiatry Res 176:85–87.
   PubMed Web of Science ®Google Scholar
• Karhunen T, Tilgmann C, Ulmanen I, Panula P. 1995. Catechol- O-methyltransferase (COMT) in rat brain: immunoelectron microscopic study with an antiserum against rat recombinant COMT protein. Neurosci Lett 187:57–60.
   Google Scholar
• Kato M, Serretti A. 2008. Review and meta-analysis of antidepressant pharmacogenetic findings in major depressive disorder. Mol Psychiatry 15:473–500.
   PubMed Web of Science ®Google Scholar
• Kessler RC, Berglund P, Demler O, Jin R, Koretz D, Merikangas KR, et al. 2003. The epidemiology of major depressive disorder: results from the national comorbidiy survey replication (NCS-R). JAMA 289:3095–3105.
   PubMed Web of Science ®Google Scholar
• Kind P. 1996. The EuroQoL instrument: an index of health-related quality of life. Quality of life and pharmacoeconomics in clinical trials. B. Spilker. Philadelphia (PA): Lippincott-Raven Publishers, pp. 191–201.
   Google Scholar
• Kocabas NA, Faghel C, Barreto M, Kasper S, Linotte S, Mendlewicz J, et al. 2010. The impact of catechol-O-methyltransferase SNPs and haplotypes on treatment response phenotypes in major depressive disorder: a case-control association study. Int Clin Psychopharmacol 25:218–227.
   PubMed Web of Science ®Google Scholar
• Koks S, Nikopensius T, Koido K, Maron E, Altmäe S, Heinaste E, et al. 2006. Analysis of SNP profiles in patients with major depressive disorder. Int J Neuropsychopharmacol 9:167–174.
   PubMed Web of Science ®Google Scholar
• Lachman HM, Morrow B, Shprintzen R, Veit S, Parsia SS, Faedda G, et al. 1996. Association of codon 108/158 catechol-O-methyltransferase gene polymorphism with the psychiatric manifestations of velo-cardio-facial syndrome. Am J Med Genet 67:468–472.
   PubMed Web of Science ®Google Scholar
• Massat I, Kocabas NA, Crisafulli C, Chiesa A, Calati R, Linotte S, et al. 2011. COMT and age at onset in mood disorders: A replication and extension study. Neurosci Lett 498:218–221.
   PubMed Web of Science ®Google Scholar
• Massat I, Souery D, Del-Favero J, Nothen M, Blackwood D, Muir W, et al. 2005. Association between COMT (Val(158)Met) functional polymorphism and early onset in patients with major depressive disorder in a European multicenter genetic association study. Mol Psychiatry 10:598–605.
   PubMed Web of Science ®Google Scholar
• Ohara K, Nagai M, Suzuki Y, Ohara K. 1998. Low activity allele of catechol-o-methyltransferase gene and Japanese unipolar depression. Neuroreport 9:1305–1308.
   PubMed Web of Science ®Google Scholar
• Phillips PC. 2008. Epistasis–the essential role of gene interactions in the structure and evolution of genetic systems. Nat Rev Genet 9:855–867.
   PubMed Web of Science ®Google Scholar
• Riedel M, Moller HJ, Obermeier M, Schennach-Wolff R, Bauer M, Adli M, et al. 2010. Response and remission criteria in major depression - A validation of current practice. J Psychiatr Res 44:1063–1068.
   PubMed Web of Science ®Google Scholar
• Risch N, Herrell R, Lehner T, Liang KY, Eaves L, Hoh J, et al. 2009. Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis. JAMA 301:2462–2471.
   PubMed Web of Science ®Google Scholar
• Segurado R, Bellgrove MA, Manconi F, Gill M, Hawi Z. 2011. Epistasis between neurochemical gene polymorphisms and risk for ADHD. Eur J Hum Genet 19:577–582.
   Google Scholar
• Serretti A, Chiesa A. 2012. The challenge of uncovering the genetics of anxiety: An editorial comment to Arias B, Aguilera M, Moya J et al. ‘The role of genetic variability in the SLC6A4, BDNF and GABRA6 genes in anxiety-related traits’ (2). Acta Psychiatr Scand 125:185–186.
   Google Scholar
• Serretti A, Rotondo A, Lorenzi C, Smeraldi E, Cassano GB. 2006. Catechol-O-methyltransferase gene variants in mood disorders in the Italian population. Psychiatr Genet 16:181–182.
   PubMed Web of Science ®Google Scholar
• Sheehan DV, Lecrubier Y, Sheehan KH, Amorim P, Janavs J, Weiller E, et al. 1998. The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry 59:22–33;quiz 34–57.
   PubMed Web of Science ®Google Scholar
• StatSoft I. 1995. STATISTICA per Windows. Tulsa, OK: StatSoft.
   Google Scholar
• Szegedi A, Rujescu D, Tadic A, Müller MJ, Kohnen R, Stassen HH, Dahmen N. 2005. The catechol-O-methyltransferase Val108/158Met polymorphism affects short-term treatment response to mirtazapine, but not to paroxetine in major depression. Pharmacogenomics J 5:49–53.
   PubMed Web of Science ®Google Scholar
• van Munster BC, de Rooij SE, Yazdanpanah M, Tienari PJ, Pitkälä KH, Osse RJ, et al. 2010. The association of the dopamine transporter gene and the dopamine receptor 2 gene with delirium, a meta-analysis. Am J Med Genet B Neuropsychiatr Genet 153B:648–655.
   PubMed Web of Science ®Google Scholar
• Wang Y, Liu X, Yu Y, Han Y, Wei J, Collier D, et al. 2012. The role of single nucleotide polymorphism of D2 dopamine receptor gene on major depressive disorder and response to antidepressant treatment. Psychiatry Res 200:1047–1050.
   Google Scholar
• Xu Z, Zhang Z, Shi Y, Pu M, Yuan Y, Zhang X, Li L. 2011. Influence and interaction of genetic polymorphisms in catecholamine neurotransmitter systems and early life stress on antidepressant drug response. J Affect Disord 133:165–173.
   Google Scholar
• Zimmerman M, Mattia JI, Posternak MA. 2002. Are subjects in pharmacological treatment trials of depression representative of patients in routine clinical practice?. Am J Psychiatry 159: 469–473.
   PubMed Web of Science ®Google Scholar