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Original Article

International web survey shows high prevalence of symptomatic testosterone deficiency in men

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Pages 10-15 | Received 07 Mar 2010, Accepted 02 Jul 2010, Published online: 09 Sep 2010

References

  • Feeley R, Saad F, Guay A, Traish A. Testosterone in men's health: a new role for an old hormone. J Men's Health 2009;6:169–176.
  • Traish A, Guay A, Feeley R, Saad F. The dark side of testosterone deficiency. I. Metabolic syndrome and erectile dysfunction. J Androl 2009;30:10–22.
  • Traish A, Saad F, Guay A. The dark side of testosterone deficiency. II. Type 2 diabetes and insulin resistance. J Androl 2009;30:23–32.
  • Traish A, Saad F, Feeley R, Guay A. The dark side of testosterone deficiency. III. Cardiovascular disease. J Androl 2009;30:477–494.
  • Fink HA, Ewing SK, Ensrud KE, Barrett-Connor E, Taylor BC, Cauley JA, Orwoll ES. Association of testosterone and estradiol deficiency with osteoporosis and rapid bone loss in older men. J Clin Endocrinol Metab 2006;91:3908–3915.
  • Drummond ES, Harvey AR, Martins RN. Androgens and Alzheimer's disease. Curr Opin Endocrinol Diabetes Obes 2009;16:254–259.
  • Makhlouf AA, Mohamed MA, Seftel AD, Neiderberger C. Hypogonadism is associated with overt depression symptoms in men with erectile dysfunction. Int J Impot Res 2008;20:157–161.
  • Srinivas-Shankar U, Roberts SA, Connolly MJ, O'Connell MD, Adams JE, Oldham JA, Wu FC. Effects of testosterone on muscle strength, physical function, body composition, and quality of life in intermediate-frail and frail elderly men: a randomized, double-blind, placebo-controlled study. J Clin Endocrinol Metab 2010;95:639–650.
  • Shores MM, Matsumoto AM, Sloan KL, Kivlahan DR. Low serum testosterone and mortality in male veterans. Arch Intern Med 2006;166:1660–1665.
  • Heufelder A, Saad F, Bunck M, Gooren L. Fifty-two-week treatment with diet and exercise plus transdermal testosterone reverses the metabolic syndrome and improves glycemic control in men with newly diagnosed type 2 diabetes and subnormal plasma testosterone. J Androl 2009;30:726–733.
  • Mathur A, Malkin C, Saeed B, Muthusamy R, Jones T, Channer K. Long-term benefits of testosterone replacement therapy on angina threshold and atheroma in men. Eur J Endocrinol/Eur Federation Endocrine Soc 2009;161:443–449.
  • Heinemann LAJ, Zimmermann T, Vermeulen A, Thiel C, Hummel W. A new ‘aging males' symptoms’ (AMS) rating scale. Aging Male 1999;2:105–114.
  • Heinemann LA, Moore C, Dinger JC, Stoehr D. Sensitivity as outcome measure of androgen replacement: the AMS scale. Health Qual Life Outcomes 2006;4:23.
  • Behre HM, Heinemann L, Morales A, Pexman-Fieth C. Rationale, design and methods of the ESPRIT study: energy, sexual desire and body proportions with androgel, testosterone 1% gel therapy, in hypogonadal men. Aging Male 2008;11:101–106.
  • Morley JE, Charlton E, Patrick P, Kaiser FE, Cadeau P, McCready D, Perry HM. Validation of a screening questionnaire for androgen deficiency in aging males. Metabolism 2000;49:1239–1242.
  • Myon E, Martin N, Taieb C, Heinemann LA. Experiences with the French aging males' symptoms (AMS) scale. Aging Male 2005;8:184–189.
  • Yasuda M, Furuya K, Yoshii T, Ide H, Muto S, Horie S. Low testosterone level of middle-aged Japanese men – the association between low testosterone levels and quality-of-life. J Men's Health Gender 2007;4:149–155.
  • Guay A, Seftel AD, Traish A. Hypogonadism in men with erectile dysfunction may be related to a host of chronic illnesses. Int J Impot Res 2010;22:9–19.
  • Carruthers M. The paradox dividing testosterone deficiency symptoms and androgen assays: a closer look at the cellular and molecular mechanisms of androgen action. J Sex Med 2008;5:998–1012.
  • Heinemann LA. Aging Males' Symptoms scale: a standardized instrument for the practice. J Endocrinol Invest 2005;28:34–38.
  • Carruthers M, Trinick TR, Jankowska E, Traish AM. Are the adverse effects of glitazones linked to induced testosterone deficiency? Cardiovasc Diabetol 2008;7:30.
  • Carruthers M. ADAM: androgen deficiency in the adult male – causes, diagnosis and treatment. London and New York: Taylor & Francis; 2004.
  • Smith KW, Feldman HA, McKinlay JB. Construction and field validation of a self-administered screener for testosterone deficiency (hypogonadism) in ageing men. Clin Endocrinol (Oxf) 2000;53:703–711.
  • The Institute of Public Health in Ireland. Second Report of the Irish Diabetes Prevalence Working Group. Belfast: The Institute of Public Health in Ireland; 2007.
  • Stanworth R, Jones T. Testosterone in obesity, metabolic syndrome and type 2 diabetes. Front Horm Res 2009;37:74–90.
  • Moore C, Huebler D, Zimmermann T, Heinemann LA, Saad F, Thai DM. The Aging Males' Symptoms scale (AMS) as outcome measure for treatment of androgen deficiency. Eur Urol 2004;46:80–87.
  • Werner AA. The male climacteric: report of two hundred and seventy-three cases. J Am Med Assoc 1946;132:188–194.
  • Zitzmann M, Faber S, Nieschlag E. Association of specific symptoms and metabolic risks with serum testosterone in older men. J Clin Endocrinol Metab 2006;91:4335–4343.
  • Morales A, Spevack M, Emerson L, Kuzmarov I, Casey R, Black A, Tremblay R. Adding to the controversy: pitfalls in the diagnosis of testosterone deficiency syndromes with questionnaires and biochemistry. Aging Male 2007;10:57–65.
  • T'Sjoen G, Feyen E, De Kuyper P, Comhaire F, Kaufman JM. Self-referred patients in an aging male clinic: much more than androgen deficiency alone. Aging Male 2003;6:157–165.
  • Morley JE, Perry HM, III, Kevorkian RT, Patrick P. Comparison of screening questionnaires for the diagnosis of hypogonadism. Maturitas 2006;53:424–429.
  • Miwa Y, Kaneda T, Yokoyama O. Correlation between the Aging Males' Symptoms Scale and sex steroids, gonadotropins, dehydroepiandrosterone sulfate, and growth hormone levels in ambulatory men. J Sex Med 2006;3:723–726.
  • Carruthers M, Trinick TR, Wheeler MJ. The validity of androgen assays. Aging Male 2007;10:165–172.
  • Black AM, Day AG, Morales A. The reliability of clinical and biochemical assessment in symptomatic late-onset hypogonadism: can a case be made for a 3-month therapeutic trial? BJU Int 2004;94:1066–1070.
  • Carruthers M. Time for international action on treating testosterone deficiency syndrome. Aging Male 2009;12:21–28.