Mild thyroid hormone excess is associated with a decreased physical function in elderly men

References

• Schneider EL, Guralnik JM. The aging of America. Impact on health care costs. JAMA 1990;263:2335–2340.
   PubMed Web of Science ®Google Scholar
• Ceda GP, Dall’Aglio E, Maggio M, Lauretani F, Bandinelli S, Falzoi C, Grimaldi W, et al. Clinical implications of the reduced activity of the GH-IGF-I axis in older men. J Endocrinol Invest 2005;28:96–100.
   PubMedGoogle Scholar
• Valenti G, Denti L, Maggio M, Ceda G, Volpato S, Bandinelli S, Ceresini G, et al. Effect of DHEAS on skeletal muscle over the life span: the InCHIANTI study. J Gerontol A Biol Sci Med Sci 2004;59:466–472.
   PubMed Web of Science ®Google Scholar
• Ceresini G, Lauretani F, Maggio M, Ceda GP, Morganti S, Usberti E, Chezzi C, et al. Thyroid function abnormalities and cognitive impairment in elderly people: results of the Invecchiare in Chianti study. J Am Geriatr Soc 2009;57:89–93.
   PubMed Web of Science ®Google Scholar
• Biondi B, Cooper DS. The clinical significance of subclinical thyroid dysfunction. Endocr Rev 2008;29:76–131.
   PubMed Web of Science ®Google Scholar
• Brennan MD, Powell C, Kaufman KR, Sun PC, Bahn RS, Nair KS. The impact of overt and subclinical hyperthyroidism on skeletal muscle. Thyroid 2006;16:375–380.
   PubMed Web of Science ®Google Scholar
• Lauretani F, Russo CR, Bandinelli S, Bartali B, Cavazzini C, Di Iorio A, Corsi AM, et al. Age-associated changes in skeletal muscles and their effect on mobility: an operational diagnosis of sarcopenia. J Appl Physiol 2003;95:1851–1860.
   PubMed Web of Science ®Google Scholar
• Heeringa J, Hoogendoorn EH, van der Deure WM, Hofman A, Peeters RP, Hop WC, den Heijer M, et al. High-normal thyroid function and risk of atrial fibrillation: the Rotterdam study. Arch Intern Med 2008;168:2219–2224.
   Google Scholar
• Ferrucci L, Bandinelli S, Benvenuti E, Di Iorio A, Macchi C, Harris TB, Guralnik JM. Subsystems contributing to the decline in ability to walk: bridging the gap between epidemiology and geriatric practice in the InCHIANTI study. J Am Geriatr Soc 2000;48:1618–1625.
   PubMed Web of Science ®Google Scholar
• Schrager MA, Metter EJ, Simonsick E, Ble A, Bandinelli S, Lauretani F, Ferrucci L. Sarcopenic obesity and inflammation in the InCHIANTI study. J Appl Physiol 2007;102:919–925.
   PubMed Web of Science ®Google Scholar
• Bandinelli S, Benvenuti E, Del Lungo I, Baccini M, Benvenuti F, Di Iorio A, Ferrucci L. Measuring muscular strength of the lower limbs by hand-held dynamometer: a standard protocol. Aging (Milano) 1999;11:287–293.
   Google Scholar
• Rantanen T, Guralnik JM, Foley D, Masaki K, Leveille S, Curb JD, White L. Midlife hand grip strength as a predictor of old age disability. JAMA 1999;281:558–560.
   PubMed Web of Science ®Google Scholar
• Rantanen T, Masaki K, Foley D, Izmirlian G, White L, Guralnik JM. Grip strength changes over 27 yr in Japanese-American men. J Appl Physiol 1998;85:2047–2053.
   PubMed Web of Science ®Google Scholar
• Rittweger J, Beller G, Ehrig J, Jung C, Koch U, Ramolla J, Schmidt F, et al. Bone-muscle strength indices for the human lower leg. Bone 2000;27:319–326.
   PubMed Web of Science ®Google Scholar
• Guralnik JM, Simonsick EM, Ferrucci L, Glynn RJ, Berkman LF, Blazer DG, Scherr PA, Wallace RB. A short physical performance battery assessing lower extremity function: association with self-reported disability and prediction of mortality and nursing home admission. J Gerontol 1994;49:M85–M94.
   PubMedGoogle Scholar
• Lauretani F, Bandinelli S, Strotmeyer ES, Corsi AM, Di Iorio A, Guralnik JM, Ferrucci L. Erythropoietin and polyneuropathy in older persons. Mech Ageing Dev 2008;129:299–303.
   Google Scholar
• Lauretani F, Bandinelli S, Bartali B, Di Iorio A, Giacomini V, Corsi AM, Guralnik JM, Ferrucci L. Axonal degeneration affects muscle density in older men and women. Neurobiol Aging 2006;27:1145–1154.
   PubMed Web of Science ®Google Scholar
• Radloff LS The CES-D Scale: a self-report depression scale for research in the general population. Appl Psychol Meas 1977; 1:385–401
   Web of Science ®Google Scholar
• Pisani P, Faggiano F, Krogh V, Palli D, Vineis P, Berrino F. Relative validity and reproducibility of a food frequency dietary questionnaire for use in the Italian EPIC centres. Int J Epidemiol 1997;26 Suppl 1:S152–S160.
   PubMed Web of Science ®Google Scholar
• Guralnik JM, Fried LP, Simonsick EM, Kasper JD, Lafferty ME. The Women’s Health and Aging Study: Health and Social Characteristics of Older Women with Disability. Bethesda, MD, National Institute on Aging. NIH Publication 1995; No. 95 4009
   Google Scholar
• Bandinelli S, Lauretani F, Boscherini V, Gandi F, Pozzi M, Corsi AM, Bartali B, et al. A randomized, controlled trial of disability prevention in frail older patients screened in primary care: the FRASI study. Design and baseline evaluation. Aging Clin Exp Res 2006;18:359–366.
   Google Scholar
• Gussekloo J, van Exel E, de Craen AJ, Meinders AE, Frölich M, Westendorp RG. Thyroid status, disability and cognitive function, and survival in old age. JAMA 2004;292:2591–2599.
   PubMed Web of Science ®Google Scholar
• van den Beld AW, Visser TJ, Feelders RA, Grobbee DE, Lamberts SW. Thyroid hormone concentrations, disease, physical function, and mortality in elderly men. J Clin Endocrinol Metab 2005;90:6403–6409.
   PubMed Web of Science ®Google Scholar
• Videla LA, Sir T, Wolff C. Increased lipid peroxidation in hyperthyroid patients: suppression by propylthiouracil treatment. Free Radic Res Commun 1988;5:1–10.
   PubMed Web of Science ®Google Scholar
• Chan RS, Huey ED, Maecker HL, Cortopassi KM, Howard SA, Iyer AM, McIntosh LJ, et al. Endocrine modulators of necrotic neuron death. Brain Pathol 1996;6:481–491.
   Google Scholar
• Kinoshita K, Kawashima K, Kawashima Y, Fukuchi I, Yamamura M, Matsuoka Y. Effect of TA-0910, a novel thyrotropin-releasing hormone analog, on in vivo acetylcholine release and turnover in rat brain. Jpn J Pharmacol 1996;71:139–145.
   Google Scholar
• Kalmijn S, Mehta KM, Pols HA, Hofman A, Drexhage HA, Breteler MM. Subclinical hyperthyroidism and the risk of dementia. The Rotterdam study. Clin Endocrinol (Oxf) 2000;53:733–737.
   PubMed Web of Science ®Google Scholar
• Senovilla L, García-Sancho J, Villalobos C. Changes in expression of hypothalamic releasing hormone receptors in individual rat anterior pituitary cells during maturation, puberty and senescence. Endocrinology 2005;146:4627–4634.
   Google Scholar
• Gammage MD, Parle JV, Holder RL, Roberts LM, Hobbs FD, Wilson S, Sheppard MC, Franklyn JA. Association between serum free thyroxine concentration and atrial fibrillation. Arch Intern Med 2007;167:928–934.
   PubMedGoogle Scholar
• Müssig K, Leyhe T, Holzmüller S, Klein R, Weinert C, Saur R, Klingberg S, et al. Increased prevalence of antibodies to central nervous system tissue and gangliosides in Hashimoto’s thyroiditis compared to other thyroid illnesses. Psychoneuroendocrinology 2009;34:1252–1256.
   PubMedGoogle Scholar
• Kurne A, Aydin OF, Karabudak R. White matter alteration in a patient with Graves’ disease. J Child Neurol 2007;22:1128–1131.
   Google Scholar
• Aghini-Lombardi F, Antonangeli L, Pinchera A, Leoli F, Rago T, Bartolomei AM, Vitti P. Effect of iodized salt on thyroid volume of children living in an area previously characterized by moderate iodine deficiency. J Clin Endocrinol Metab 1997;82:1136–1139.
   Google Scholar
• Aghini Lombardi FA, Pinchera A, Antonangeli L, Rago T, Chiovato L, Bargagna S, Bertucelli B, et al. Mild iodine deficiency during fetal/neonatal life and neuropsychological impairment in Tuscany. J Endocrinol Invest 1995;18:57–62.
   Google Scholar
• Castaneda-Sceppa C, Price LL, Noel SE, Bassett Midle J, Falcon LM, Tucker KL. Physical function and health status in aging puerto rican adults: the Boston puerto rican health study. J Aging Health 2010;22:653–672.
   PubMed Web of Science ®Google Scholar
• Boelaert K, Torlinska B, Holder RL, Franklyn JA. Older subjects with hyperthyroidism present with a paucity of symptoms and signs: a large cross-sectional study. J Clin Endocrinol Metab 2010;95:2715–2726.
   PubMed Web of Science ®Google Scholar