572
Views
4
CrossRef citations to date
0
Altmetric
Research Article

A Kampo formula, saikokaryukotsuboreito, improves serum testosterone levels of castrated mice and its possible mechanism

, , , , &
Pages 17-21 | Received 17 Jul 2012, Accepted 30 Nov 2012, Published online: 22 Jan 2013

References

  • Gray A, Feldman HA, McKinlay JB, Longcope C. Age, disease, and changing sex hormone levels in middle-aged men: results of the Massachusetts Male Aging Study. J Clin Endocrinol Metab 1991;73:1016–25
  • Gray A, Berlin JA, McKinlay JB, Longcope C. An examination of research design effects on the association of testosterone and male aging: results of a meta-analysis. J Clin Epidemiol 1991;44:671–84
  • Feldman HA, Longcope C, Derby CA, et al. Age trends in the level of serum testosterone and other hormones in middle-aged men: longitudinal results from the Massachusetts male aging study. J Clin Endocrinol Metab 2002;87:589–98
  • Iwamoto T, Yanase T, Horie H, et al. Late-onset hypogonadism (LOH) and androgens: validity of the measurement of free testosterone levels in the diagnostic criteria in Japan. Int J Urol 2009;16:168–74
  • Cattabiani C, Basaria S, Ceda GP, et al. Relationship between testosterone deficiency and cardiovascular risk and mortality in adult men. J Endocrinol Invest 2012;35:104–20
  • Spark RF. Testosterone, diabetes mellitus, and the metabolic syndrome. Curr Urol Rep 2007;8:467–71
  • Amore M, Innamorati M, Costi S, et al. Partial androgen deficiency, depression, and testosterone supplementation in aging men. Int J Endocrinol 2012;2012:280724 doi: 10.1155/2012/280724
  • Morales A, Lunenfeld B. Investigation, treatment and monitoring of late-onset hypogonadism in males. Official recommendations of ISSAM. Aging Male 2002;5:74–86
  • Nigro N, Christ-Crain M. Testosterone treatment in the aging male: myth or reality? Swiss Med Wkly 2012;142:w13539. . doi: 10.44414/smw.2012.13539
  • Japan Kampo Medicines Manufactures Association. Actual use survey of Kampo formulae 2011 (in Japanese). Available from: http://www.nikkankyo.org/topix/news.html [last accessed 3 July 2012]
  • Tsujimura A, Takada S, Matsuoka Y, et al. Clinical trial of treatment with saikokaryukotsuboreito for eugonadal patients with late-inset hypogonadism-related symptoms. Aging Male 2008;11:95–9
  • Sugimoto K, Shigehara K, Izumi K, et al. Effect of combination of Saiko-ka-ryukotsu-borei-to with androgen replacement therapy for LOH syndrome. Jpn J Impot Res 2009;24:349–53
  • Tsujimura A, Miyagawa Y, Okuda H, et al. Change in cytokine levels after administration of saikokaryuukotsuboreito or testosterone in patients with symptoms of late-onset hypogonadism. Aging Male 2011;14:76–81
  • The Ministry of Health and Welfare. The guidebook of non-prescription Kampo formulae (in Japanese) (Edited by The Ministry of Health and Welfare). Tokyo: Yakugyo-jihosha Press; 1975
  • Hsu HY, Hsu CS. Commonly used Chinese herb formulas with illustrations. Long Beach (CA): Ohai Press (Oriental Healing Arts Institute); 1980
  • Alan C, Margaret H. Mammalian aromatases. Reproduction 2001;121:685–95
  • Karagiannis A, Harsoulis F. Gonadal dysfunction in systemic diseases. Eur J Endocrinol 2005;152:501–13
  • Leder BZ, Rohrer JL, Rubin SD, et al. Effects of aromatase inhibition in elderly men with low or borderline-low serum testosterone levels. J Clin Endocrinol Metab 2004;89:1174–80
  • de Boer H, Verschoor L, Ruinemans-Koerts J, Jansen M. Letrozole normalizes serum testosterone in severely obese men with hypogonadotropic hypogonadism. Diabetes Obes Metab 2005;7:211–15
  • Burnett-Bowie SA, Roupenian KC, Dere ME, et al. Effects of aromatase inhibition in hypogonadal older men: a randomized, double-blind, placebo-controlled trial. Clin Endocrinol (Oxf) 2009;70:116–23
  • Ito T, Murai S, Saito H, et al. Effect of Saiko-ka-ryukotsu-borei-to on the monoamine-related substances in several regions of mouse brain. Nihon Toyo Igaku Zasshi (Jpn J Orient Med) 1994;45:97–106
  • Hayes FJ, Seminara SB, Decruz S, et al. Aromatase inhibition in the human male reveals a hypothalamic site of estrogen feedback. J Clin Endocrinol Metab 2000;85:3027–35
  • Norimoto H, Yamaguchi H, Morimoto Y. Effects of anastrazole on serum testosterone and seminal vesicles weight in male mice with testosterone deficiency. The 8th European congress on Menopause; 2009 May 16–20; London, UK: Scientific Programme; 2009;49pp
  • Terasawa K. Evidence-based reconstruction of Kampo medicine: Part-III – how should Kampo be evaluated? Evid-Based Complement Alternat Med 2004;1:219–22

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.