15
Views
1
CrossRef citations to date
0
Altmetric
Research Article

Cyclophosphamide reduces dectin-1 expression in the lungs of naive and Aspergillus fumigatus-infected mice

, , , , &
Pages 303-309 | Received 14 May 2009, Accepted 18 Jun 2009, Published online: 08 Feb 2010

References

  • Latge JP.. Aspergillus fumigatus and aspergillosis. Clin Microbiol Rev 1999; 12: 310–50.
  • Soubani AO, Chandrasekar PH. The clinical spectrum of pulmonary aspergillosis. Chest 2002; 121: 1988–1999.
  • Kontoyiannis DP, Bodey GP. Invasive aspergillosis in 2002: an update. Eur J Clin Microbiol Infect Dis 2002; 21: 161–172.
  • Brown GD, Gordon S. Immune recognition of fungal beta-glucans. Cell Microbiol 2005; 7: 471–479.
  • van de Veerdonk FL, Kullberg BJ, van der Meer JW, Gow NA, Netea MG. Host-microbe interactions: innate pattern recognition of fungal pathogens. Curr Opin Microbiol 2008; 11: 305–312.
  • Suram S, Brown GD, Ghosh M, . Regulation of cytosolic phospholipase A2 activation and cyclooxygenase 2 expression in macrophages by the beta-glucan receptor. J Biol Chem 2006; 281: 5506–5514.
  • Brown GD, Gordon S. Immune recognition. A new receptor for beta-glucans. Nature 2001; 413: 36–37.
  • Brown GD. Dectin-1: a signalling non-TLR pattern-recognition receptor. Nat Rev Immunol 2006; 6: 33–43.
  • Ariizumi K, Shen GL, Shikano S, . Identification of a novel, dendritic cell-associated molecule, dectin-1, by subtractive cDNA cloning. J Biol Chem 2000; 275: 20157–20167.
  • Taylor PR, Brown GD, Reid DM. The beta-glucan receptor, dectin-1, is predominantly expressed on the surface of cells of the monocyte/macrophage and neutrophil lineages. J Immunol 2002; 169: 3876–3882.
  • Herre J, Gordon S, Brown GD. Dectin-1 and its role in the recognition of beta-glucans by macrophages. Mol Immunol 2004; 40: 869–876.
  • Kennedy AD, Willment JA, Dorward DW, . Dectin-1 promotes fungicidal activity of human neutrophils. Eur J Immunol 2007; 37: 467–478.
  • Steele C, Rapaka RR, Metz A, . The beta-glucan receptor dectin-1 recognizes specific morphologies of Aspergillus fumigatus. PLoS Pathog 2005; 1: e42–
  • Vallor AC, Kirkpatrick WR, Najvar LK, . Assessment of Aspergillus fumigatus burden in pulmonary tissue of guinea pigs by quantitative PCR, galactomannan enzyme immunoassay, and quantitative culture. Antimicrob Agents Chemother 2008; 52: 2593–2598.
  • Philippe B, Ibrahim-Granet O, Prevost MC, . Killing of Aspergillus fumigatus by alveolar macrophages is mediated by reactive oxidant intermediates. Infect Immun 2003; 71: 3034–3042.
  • Balloy V, Huerre M, Latge JP, Chignard M. Differences in patterns of infection and inflammation for corticosteroid treatment and chemotherapy in experimental invasive pulmonary aspergillosis. Infect Immun 2005; 73: 494–503.
  • Werner JL, Metz AE, Horn D, . Requisite role for the dectin-1 beta-glucan receptor in pulmonary defense against Aspergillus fumigatus. J Immunol 2009; 182: 4938–4946.
  • Klis FM, Mol P, Hellingwerf K, Brul S. Dynamics of cell wall structure in Saccharomyces cerevisiae. FEMS Microbiol Rev 2002; 26: 239–256.
  • Hohl TM, Van Epps HL, Rivera A, . Aspergillus fumigatus triggers inflammatory responses by stage-specific beta-glucan display. PLoS Pathog 2005; 1: e30–
  • Gantner BN, Simmons RM, Canavera SJ, Akira S, Underhill DM. Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2. J Exp Med 2003; 197: 1107–1117.
  • Brown GD, Herre J, Williams DL, . Dectin-1 mediates the biological effects of beta-glucans. J Exp Med 2003; 197: 1119–1124.
  • Luther K, Torosantucci A, Brakhage AA, Heesemann J, Ebel F. Phagocytosis of Aspergillus fumigatus conidia by murine macrophages involves recognition by the dectin-1 beta-glucan receptor and Toll-like receptor 2. Cell Microbiol 2007; 9: 368–381.
  • Steele C, Marrero L, Swain S, . Alveolar macrophage-mediated killing of Pneumocystis carinii f. sp. muris involves molecular recognition by the Dectin-1 beta-glucan receptor. J Exp Med 2003; 198: 1677–1688.
  • Gantner BN, Simmons RM, Underhill DM. Dectin-1 mediates macrophage recognition of Candida albicans yeast but not filaments. Embo J 2005; 24: 1277–1286.
  • Viriyakosol S, Fierer J, Brown GD, Kirkland TN. Innate immunity to the pathogenic fungus Coccidioides posadasii is dependent on Toll-like receptor 2 and Dectin-1. Infect Immun 2005; 73: 1553–1560.
  • Hunninghake GW, Fauci AS. Immunological reactivity of the lung. IV. Effect of cyclophosphamide on alveolar macrophage cytotoxic effector function. Clin Exp Immunol 1977; 27: 555–559.
  • Cooper JA, Jr, Merrill WW, Reynolds HY. Cyclophosphamide modulation of bronchoalveolar cellular populations and macrophage oxidative metabolism. Possible mechanisms of pulmonary pharmacotoxicity. Am Rev Respir Dis 1986; 134: 108–114.
  • Santosuosso M, Divangahi M, Zganiacz A, Xing Z. Reduced tissue macrophage population in the lung by anticancer agent cyclophosphamide: restoration by local granulocyte macrophage-colony-stimulating factor gene transfer. Blood 2002; 99: 1246–1252.
  • Bellocchio S, Montagnoli C, Bozza S, . The contribution of the Toll-like/IL-1 receptor superfamily to innate and adaptive immunity to fungal pathogens in vivo. J Immunol 2004; 172: 3059–3069.
  • Mehrad B, Strieter RM, Standiford TJ. Role of TNF-alpha in pulmonary host defense in murine invasive aspergillosis. J Immunol 1999; 162: 1633–1640.
  • Willment JA, Lin HH, Reid DM, . Dectin-1 expression and function are enhanced on alternatively activated and GM-CSF-treated macrophages and are negatively regulated by IL-10, dexamethasone, and lipopolysaccharide. J Immunol 2003; 171: 4569–4573.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.