The importance of pro-inflammatory and anti-inflammatory cytokines in Pneumocystis jirovecii pneumonia

References

• Thomas CF Jr, Limper AH. Pneumocystis pneumonia. N Engl J Med 2004; 350: 2487–2498.
   PubMed Web of Science ®Google Scholar
• Sepkowitz KA. Opportunistic infections in patients with and patients without acquired immunodeficiency syndrome. Clin Inf Dis 2002; 34: 1098–1177.
   PubMed Web of Science ®Google Scholar
• Tasaka S, Tokuda H, Sakai F, et al. Comparisons of clinical radiological features of pneumocystis pneumonia between malignancy cases and acquired immunodeficiency syndrome cases: A multicenter study. Intern Med 2010; 49: 273–281.
   PubMed Web of Science ®Google Scholar
• Limper AH, Offord KP, Smith TF, Martin WJ 2nd. Pneumocystis carinii pneumonia: differences in lung parasite number and inflammation in patients with and without AIDS. Am Rev Respir Dis 1989; 140: 1204–1209.
   PubMed Web of Science ®Google Scholar
• Sepkowitz KA. Pneumocystis carinii pneumonia in patients without AIDS. Clin Inf Dis 17 1993; 17(Suppl. 2): S416–422.
   Google Scholar
• Benfield TL, Vestbo J, Junge J, et al. Prognostic value of interleukin-8 in AIDS-associated Pneumocystis carinii pneumonia. Am J Respir Crit Care Med 1995; 151: 1058–1062.
   PubMed Web of Science ®Google Scholar
• The National Institutes of Health-University of California Expert Panel for Corticosteroids as Adjunctive Therapy for Pneumocystis Pneumonia. Consensus statement on the use of corticosteroids as adjunctive therapy for Pneumocystis pneumonia in the Acquired Immunodeficiency Syndrome. N Engl J Med 1990; 323: 1500–1504.
   PubMed Web of Science ®Google Scholar
• Wright TW, Gigliotti F, Finkelstein JN, et al. Immune-mediated inflammation directly impairs pulmonary function, contributing to the pathogenesis of Pneumocystis carinii pneumonia. J Clin Invest 1999; 104: 1307–1317.
   PubMed Web of Science ®Google Scholar
• Gigliotti F, Wright TW. Immunogenesis of pneumocystis carinii pneumonia. Expert Rev Mol Med 2005; 7: 1–16.
   PubMedGoogle Scholar
• Perenboom RM, van Schijndel AC, Beckers P, et al. Cytokine profiles in bronchoalveolar lavage fluid and blood in HIV-seronegative patients with pneumocystis carinii pneumonia. Eur J Clin Invest 1996; 26: 159–166.
   Google Scholar
• Iriart X, Witkowski B, Courtais C, et al. Cellular and cytokine changes in the alveolar environment among immunocompromised patients during Pneumocystis Jirovecii infection. Med Mycol 2010; 48: 1075–1087.
   Web of Science ®Google Scholar
• Benfield TL, van Steenwijk R, Nielsen TL, et al. Interleukin-8 and eicosanoid production in the lung during moderate to severe pneumocystis carinii pneumonia in AIDS: a role of interleukin-8 in the pathogenesis of P. carinii pneumonia. Respir Med 1995; 89: 285–290.
   Google Scholar
• Benfield TL, Lundgren B, Shelhamer JH, Lundgren JD. Pneumocystis carinii major surface glycoprotein induces interleukin-8 and monocyte chemoattractant protein-1 release from a human alveolar epithelial cell line. Eur J Clin Invest 1999; 29(8): 717–722.
   Google Scholar
• Wang J, Gigliotti F, Bhagwat SP, Maggirwar SB, Wright TW. Pneumocystis stimulates MCP-1 production by alveolar epithelial cells through a JNK-dependent mechanism. Am J Physiol Lung Cell Mol Physiol 2007; 292: L1495–1505.
   Google Scholar
• Wright TW, Johnston CJ, Harmsen AG, Finkelstein JN. Analysis of cytokine mRNA profiles in the lungs of Pneumocystis carinii-infected mice. Am J Respir Cell Mol Biol 1997; 17: 491–500.
   PubMed Web of Science ®Google Scholar
• Wright TW, Johnston CJ, Harmsen AG, Finkelstein JN. Chemokine gene expression during Pneumocystis carinii-driven pulmonary inflammation. Infect Immun 1999; 67: 3452–3460.
   PubMedGoogle Scholar
• Moore KW, de Waal Malefyt R, Coffman RL, O’Garra A. Interleukin-10 and the interleukin-10 receptor. Ann Rev Immunol 2001; 19: 683–765.
   PubMed Web of Science ®Google Scholar
• Qureshi MH, Harmsen AG, Garvy BA. IL-10 modulates host response and lung damage induced by Pneumocystis carinii infection. J Immunol 2003; 170: 1002–1009.
   Google Scholar
• Ruan S, Tate C, Lee JJ, et al. Local delivery of the viral interleukin-10 gene suppresses tissue inflammation in murine pneumocystis carinii infection. Infect Immun 2002; 70: 6107–6113.
   Google Scholar
• Blobe GC, Schiemann WP, Lodish HF. Role of transforming growth factor beta in human disease. N Engl J Med 2000; 342: 1350–1358.
   PubMed Web of Science ®Google Scholar
• Letterio JJ, Roberts AB. Regulation of immune responses by TGF-beta. Ann Rev Immunol 1998; 16: 137–161.
   PubMed Web of Science ®Google Scholar
• Angelici E, Spezzano M, Vaccari S, et al. Urokinase plasminogen activator and TGF-β production in immunosuppressed patients with and without P. Jiroveci infection. Microb Pathog 2006; 41: 1–9.
   Google Scholar
• Ray CA, Lasbury ME, Durant PJ, et al. Transforming growth factor-β activation and signaling in the alveolar environment during Pneumocystis pneumonia. J Eukaryot Microbiol 2006; 53(Suppl. 1): S127–129.
   Google Scholar