Age-associated development of inflammation in Wistar rats: Effects of caloric restriction

References

• Bartke A. (2007). Aging: all in the head? Cell Metab 6:153–4.
   PubMed Web of Science ®Google Scholar
• Carvalheira JB, Ribeiro EB, Araujo EP, Guimaraes RB, Telles MM, Torsoni M, Gontijo JA, Velloso LA, Saad MJ. (2003). Selective impairment of insulin signalling in the hypothalamus of obese Zucker rats. Diabetologia 46:1629–40.
   PubMed Web of Science ®Google Scholar
• Carvalho CR, Brenelli SL, Silva AC, Nunes AL, Velloso LA, Saad MJ. (1996). Effect of aging on insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of rats. Endocrinology 137:151–9.
   PubMed Web of Science ®Google Scholar
• De Souza CT, Araujo EP, Bordin S, Ashimine R, Zollner RL, Boschero AC, Saad MJ, Velloso LA. (2005). Consumption of a fat-rich diet activates a proinflammatory response and induces insulin resistance in the hypothalamus. Endocrinology 146:4192–9.
   PubMed Web of Science ®Google Scholar
• Einstein FH, Huffman DM, Fishman S, Jerschow E, Heo HJ, Atzmon G, Schechter C, Barzilai N, Muzumdar RH. (2010). Aging per se increases the susceptibility to free fatty acid–induced insulin resistance. J Gerontol A Biol Sci Med Sci 65:800–8.
   PubMed Web of Science ®Google Scholar
• Escrivá F, Agote M, Rubio E, Molero JC, Pascual-Leone AM, Andres A, Satrustegui J, Carrascosa JM. (1997). In vivo insulin-dependent glucose uptake of specific tissues is decreased during aging of mature Wistar rats. Endocrinology 138:49–54.
   PubMed Web of Science ®Google Scholar
• Escrivá F, Gavete ML, Fermin Y, Perez C, Gallardo N, Alvarez C, Andres A, Ros M, Carrascosa JM. (2007). Effect of age and moderate food restriction on insulin sensitivity in Wistar rats: role of adiposity. J Endocrinol 194:131–41.
   PubMed Web of Science ®Google Scholar
• Facchini FS, Hua N, Abbasi F, Reaven GM. (2001). Insulin resistance as a predictor of age-related diseases. J Clin Endocrinol Metab 86:3574–8.
   PubMed Web of Science ®Google Scholar
• Fernández, CM, Molto E, Gallardo N, del AA, Martinez C, Andres A, Ros M, Carrascosa JM, Arribas C. (2009). The expression of rat resistin isoforms is differentially regulated in visceral adipose tissues: effects of aging and food restriction. Metabolism 58:204–11.
   PubMed Web of Science ®Google Scholar
• Fernández-Galaz C, Fernández-Agullo T, Perez C, Peralta S, Arribas C, Andres A, Carrascosa JM, Ros M. (2002). Long-term food restriction prevents ageing-associated central leptin resistance in wistar rats. Diabetologia 45:997–1003.
   PubMed Web of Science ®Google Scholar
• Gallardo, N., Bonzón-Kukichenco, E, Moltó, E., Fernández-Agulló, T., Martinez, C., Ros, M., Carrascosa, J. M., and Andrés, A. (2008). Nuclear levels of ChREBP correlates with hepatic triglyceride accumulation in insulin-resistant old rats. Obesity 16:S262.
   Web of Science ®Google Scholar
• García-San Frutos M, Fernández-Agullo T, De Solis AJ, Andres A, Arribas C, Carrascosa JM, Ros M. (2007). Impaired central insulin response in aged Wistar rats: role of adiposity. Endocrinology 148:5238–47.
   PubMed Web of Science ®Google Scholar
• Heilbronn LK, Campbell LV. (2008). Adipose tissue macrophages, low grade inflammation and insulin resistance in human obesity. Curr Pharm Des 14:1225–30.
   PubMed Web of Science ®Google Scholar
• Hotamisligil GS, Shargill NS, Spiegelman BM. (1993). Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science 259:87–91.
   PubMed Web of Science ®Google Scholar
• Konner AC, Bruning JC. (2011). Toll-like receptors: linking inflammation to metabolism. Trends Endocrinol Metab 22:16–23.
   PubMed Web of Science ®Google Scholar
• Li P, Lu M, Nguyen MT, Bae EJ, Chapman J, Feng D, Hawkins M, Pessin JE, Sears DD, Nguyen AK, et al. (2010). Functional heterogeneity of CD11c-positive adipose tissue macrophages in diet-induced obese mice. J Biol Chem 285:15333–45.
   PubMed Web of Science ®Google Scholar
• Lowell BB, Shulman GI. (2005). Mitochondrial dysfunction and type 2 diabetes. Science 307:384–7.
   PubMed Web of Science ®Google Scholar
• Mootha VK, Lindgren CM, Eriksson KF, Subramanian A, Sihag S, Lehar J, Puigserver P, Carlsson E, Ridderstrale M, Laurila E, et al. (2003). PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet 34:267–273.
   PubMed Web of Science ®Google Scholar
• Morgan TE, Xie Z, Goldsmith S, Yoshida T, Lanzrein AS, Stone D, Rozovsky I, Perry G, Smith MA, Finch CE. (1999). The mosaic of brain glial hyperactivity during normal ageing and its attenuation by food restriction. Neuroscience 89:687–99.
   PubMed Web of Science ®Google Scholar
• Nakatani Y, Kaneto H, Kawamori D, Yoshiuchi K, Hatazaki M, Matsuoka TA, Ozawa K, Ogawa S, Hori M, Yamasaki Y, et al. (2005). Involvement of endoplasmic reticulum stress in insulin resistance and diabetes. J Biol Chem 280:847–51.
   PubMed Web of Science ®Google Scholar
• Narimiya M, Azhar S, Dolkas CB, Mondon CE, Sims C, Wright DW, Reaven GM. (1984). Insulin resistance in older rats. Am J Physiol 246:E397–E404
   PubMed Web of Science ®Google Scholar
• Nguyen MT, Favelyukis S, Nguyen AK, Reichart D, Scott PA, Jenn A, Liu-Bryan R, Glass CK, Neels JG, Olefsky JM. (2007). A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways. J Biol Chem 282:35279–92.
   PubMed Web of Science ®Google Scholar
• Olefsky JM, Glass CK. (2010). Macrophages, inflammation, and insulin resistance. Annu Rev Physiol 72:219–46.
   PubMed Web of Science ®Google Scholar
• Ozcan U, Cao Q, Yilmaz E, Lee AH, Iwakoshi NN, Ozdelen E, Tuncman G, Gorgun C, Glimcher LH, Hotamisligil GS. (2004). Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science 306:457–61.
   PubMed Web of Science ®Google Scholar
• Perez C, Fernández-Galaz C, Fernández-Agullo T, Arribas C, Andres A, Ros M, Carrascosa JM. (2004). Leptin impairs insulin signaling in rat adipocytes. Diabetes 53:347–53.
   PubMed Web of Science ®Google Scholar
• Petersen KF, Befroy D, Dufour S, Dziura J, Ariyan C, Rothman DL, DiPietro L, Cline GW, Shulman GI. (2003). Mitochondrial dysfunction in the elderly: possible role in insulin resistance. Science 300:1140–42.
   PubMed Web of Science ®Google Scholar
• Serrano R, Villar M, Gallardo N, Carrascosa JM, Martinez C, Andres A. (2009). The effect of aging on insulin signalling pathway is tissue dependent: central role of adipose tissue in the insulin resistance of aging. Mech Ageing Dev 130:189–97.
   PubMed Web of Science ®Google Scholar
• Shoelson SE, Lee J, Goldfine AB. (2006). Inflammation and insulin resistance. J Clin Invest 116:1793–801.
   PubMed Web of Science ®Google Scholar
• Wang P, Mariman E, Renes J, Keijer J. (2008). The secretory function of adipocytes in the physiology of white adipose tissue. J Cell Physiol 216:3–13.
   PubMed Web of Science ®Google Scholar
• Weisberg SP, Hunter D, Huber R, Lemieux J, Slaymaker S, Vaddi K, Charo I, Leibel RL, Ferrante AW Jr. (2006). CCR2 modulates inflammatory and metabolic effects of high–fat feeding. J Clin Invest 116:115–124.
   PubMed Web of Science ®Google Scholar
• Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AW Jr. (2003). Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 112:1796–808.
   PubMed Web of Science ®Google Scholar
• Yuan M, Konstantopoulos N, Lee J, Hansen L, Li ZW, Karin M, Shoelson SE. (2001). Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta. Science 293:1673–1677.
   PubMed Web of Science ®Google Scholar
• Zhu M, de CR, Anson RM, Ingram DK, Lane MA. (2005). Caloric restriction modulates insulin receptor signaling in liver and skeletal muscle of rat. Nutrition 21:378–388.
   PubMed Web of Science ®Google Scholar