Publication Cover
Archives of Physiology and Biochemistry
The Journal of Metabolic Diseases
Volume 121, 2015 - Issue 3
224
Views
9
CrossRef citations to date
0
Altmetric
Original Article

Lack of association between leptin, leptin receptor, adiponectin gene polymorphisms and epicardial adipose tissue, abdominal visceral fat volume and atherosclerotic burden in psoriasis patients

, , , , , , & show all
Pages 103-108 | Received 18 Dec 2014, Accepted 24 Feb 2015, Published online: 30 Jun 2015

References

  • Abdel Hay RM, Rashed LA. (2011). Association between the leptin gene 2548G/A polymorphism, the plasma leptin and the metabolic syndrome with psoriasis. Exp Dermatol, 20:715–9
  • Alexopoulos N, McLean DS, Janik M, et al. (2010). Epicardial adipose tissue and coronary artery plaque characteristics. Atherosclerosis, 210:150–4
  • Aly DG, Abdallah IY, Hanafy NS, et al. (2013). Elevated serum leptin levels in nonobese patients with psoriasis. J Drugs Dermatol, 12:e25–9
  • Arita Y, Kihara S, Ouchi N, et al. (1999). Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun, 257:79–83
  • Armstrong AW, Voyles SV, Armstrong EJ, et al. (2011). A tale of two plaques: Convergent mechanisms of T-cell-mediated inflammation in psoriasis and atherosclerosis. Exp Dermatol, 20:544–9
  • Balci A, Balci DD, Yonden Z, et al. (2010). Increased amount of visceral fat in patients with psoriasis contributes to metabolic syndrome. Dermatology, 220:32–7
  • Bays HE. (2009). ‘Sick fat’, metabolic disease, and atherosclerosis. Am J Med, 122:S26–37
  • Chen YJ, Wu CY, Shen JL, et al. (2008). Psoriasis independently associated with hyperleptinemia contributing to metabolic syndrome. Arch Dermatol, 144:1571–5
  • Comuzzie AG, Funahashi T, Sonnenberg G, et al. (2001). The genetic basis of plasma variation in adiponectin, a global endophenotype for obesity and the metabolic syndrome. J Clin Endocrinol Metab, 86:4321–5
  • Davidovici BB, Sattar N, Prinz J, et al. (2010). Psoriasis and systemic inflammatory diseases: Potential mechanistic links between skin disease and co-morbid conditions. J Invest Dermatol, 130:1785–96
  • Deng J, Liu Y, Yang M, et al. (2012). Leptin exacerbates collagen-induced arthritis via enhancement of Th17 cell response. Arthritis Rheum, 64:3564–73
  • Dirnagl U, Lauritzen M. (2010). Fighting publication bias: Introducing the Negative Results section. J Cereb Blood Flow Metab, 30:1263–4
  • Dwan K, Altman DG, Arnaiz JA, et al. (2008). Systematic review of the empirical evidence of study publication bias and outcome reporting bias. Plos One, 3:e3081
  • Farooqi IS, Wangensteen T, Collins S, et al. (2007). Clinical and molecular genetic spectrum of congenital deficiency of the leptin receptor. N Engl J Med, 356:237–47
  • García-Bermúdez M, González-Juanatey C, Rodríguez-Rodríguez L, et al. (2011). Lack of association between LEP rs2167270 (19 G > A) polymorphism and disease susceptibility and cardiovascular disease in patients with rheumatoid arthritis. Clin Exp Rheumatol, 29:293–8
  • Gerdes S, Rostami-Yazdi M, Mrowietz U. (2011). Adipokines and psoriasis. Exp Dermatol, 20:81–7
  • Gisondi P, Girolomoni G. (2009). Psoriasis and atherothrombotic diseases: Disease-specific and non-disease-specific risk factors. Semin Thromb Hemost, 35:313–24
  • Gustafson B. (2010). Adipose tissue, inflammation and atherosclerosis. J Atheroscler Thromb, 17:332–41
  • Horreau C, Pouplard C, Brenaut E, et al. (2013). Cardiovascular morbidity and mortality in psoriasis and psoriatic arthritis: A systematic literature review. J Eur Acad Dermatol Venereol, 27 Suppl 3:12–29
  • Hager J, Clement K, Francke S, et al. (1998). A polymorphism in the 5' untranslated region of the human ob gene is associated with low leptin levels. Int J Obes Relat Metab Disord, 22:200–205
  • Jansson PA, Pellme F, Hammarstedt A, et al. (2003). A novel cellular marker of insulin resistance and early atherosclerosis in humans is related to impaired fat cell differentiation and low adiponectin. FASEB J, 17:1434–40
  • Johnston A, Arnadottir S, Gudjonsson JE, et al. (2008). Obesity in psoriasis: Leptin and resistin as mediators of cutaneous inflammation. Br J Dermatol, 159:342–50
  • Kara N, Aydin F, Senturk N, et al. (2007). Lack of association between the G-2548A polymorphism of the leptin gene and psoriasis in a Turkish population. Int J Dermatol, 46:1271–4
  • Karpouzis A, Tripsianis G, Gatzidou E, et al. (2014). Assessment of Leptin Gene Polymorphism rs2060713 in Psoriasis Vulgaris. ISRN Dermatol, 2014:845272
  • Li RC, Krishnamoorthy P, DerOhannessian S, et al. (2014). Psoriasis is associated with decreased plasma adiponectin levels independently of cardiometabolic risk factors. Clin Exp Dermatol, 39:19–24
  • Li WD, Reed DR, Lee JH, et al. (1999). Sequence variants in the 5' flanking region of the leptin gene are associated with obesity in women. Ann Hum Genet, 63:227–34
  • Lu Y, Chen H, Nikamo P, et al. (2013). Association of cardiovascular and metabolic disease genes with psoriasis. J Invest Dermatol, 133:836–9
  • Mazurek T, Zhang L, Zalewski A, et al. (2003). Human epicardial adipose tissue is a source of inflammatory mediators. Circulation, 108:2460–66
  • Mehta NN, Azfar RS, Shin DB, et al. (2010). Patients with severe psoriasis are at increased risk of cardiovascular mortality: Cohort study using the General Practice Research Database. Eur Heart J, 31:1000–6
  • Menzaghi C, Trischitta V, Doria A. (2007). Genetic influences of adiponectin on insulin resistance, type 2 diabetes, and cardiovascular disease. Diabetes, 56:1198–209
  • Orlova EG, Shirshev SV. (2014). Role of leptin and ghrelin in induction of differentiation of IL-17-producing and T-regulatory cells. Bull Exp Biol Med, 156:819–22
  • Pajvani UB, Hawkins M, Combs TP, et al. (2004). Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivity. J Biol Chem, 279:12152–62
  • Paracchini V, Pedotti P, Taioli E. (2005). Genetics of leptin and obesity: A HuGE review. Am J Epidemiol, 162:101–14
  • Persson J, Lindberg K, Gustafsson TP, et al. (2010). Low plasma adiponectin concentration is associated with myocardial infarction in young individuals. J Intern Med, 268:194–205
  • Piatti P, Di Mario C, Monti LD, et al. (2003). Association of insulin resistance, hyperleptinemia, and impaired nitric oxide release with in-stent restenosis in patients undergoing coronary stenting. Circulation, 108:2074–81
  • Qi L, Doria A, Manson JE, et al. (2006). Adiponectin genetic variability, plasma adiponectin, and cardiovascular risk in patients with type 2 diabetes. Diabetes, 55:1512–16
  • Qi L, Li T, Rimm E, et al. (2005). The +276 polymorphism of the APM1 gene, plasma adiponectin concentration, and cardiovascular risk in diabetic men. Diabetes, 54:1607–10
  • Reich K. (2012). The concept of psoriasis as a systemic inflammation: Implications for disease management. J Eur Acad Dermatol Venereol, 26 Suppl 2:3–11
  • Robati RM, Partovi-Kia M, Haghighatkhah HR, et al. (2014). Increased serum leptin and resistin levels and increased carotid intima-media wall thickness in patients with psoriasis: Is psoriasis associated with atherosclerosis? J Am Acad Dermatol, 71:642–8
  • Rodríguez-Rodríguez L, García-Bermúdez M, González-Juanatey C, et al. (2011). Lack of association between ADIPOQ rs266729 and ADIPOQ rs1501299 polymorphisms and cardiovascular disease in rheumatoid arthritis patients. Tissue Antigens, 77:74–8
  • Senturk N, Aydin F, Birinci A, et al. (2008). Investigation for the leptin 1 and LEP G2548A gene polymorphism in psoriasis. Eur J Dermatol, 18:343–4
  • Shibata S, Saeki H, Tada Y, et al. (2009). Serum high molecular weight adiponectin levels are decreased in psoriasis patients. J Dermatol Sci, 55:62–3
  • Stofkova A. (2009). Leptin and adiponectin: From energy and metabolic dysbalance to inflammation and autoimmunity. Endocr Regul, 43:157–68
  • Takahashi H, Tsuji H, Takahashi I, et al. (2008). Plasma adiponectin and leptin levels in Japanese patients with psoriasis. Br J Dermatol, 159:1207–8
  • Tilg H, Moschen AR. (2006). Adipocytokines: Mediators linking adipose tissue, inflammation and immunity. Nat Rev Immunol, 6:772–83
  • Torres T, Bettencourt N, Mendonca D, et al. (2014a). Epicardial adipose tissue and coronary artery calcification in psoriasis patients. J Eur Acad Dermatol Venereol, 29:270--7
  • Torres T, Chiricozzi A, Chimenti S, et al. (2014b). Genetic markers for cardiovascular disease in psoriasis: The missing piece. Mol Diagn Ther, 18:93–5
  • Wang Y, Chen J, Zhao Y, et al. (2008). Psoriasis is associated with increased levels of serum leptin. Br J Dermatol, 158:1134–5
  • Yamauchi T, Kamon J, Minokoshi Y, et al. (2002). Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat Med, 8:1288–95
  • Zhu KJ, Zhang C, Li M, et al. (2013). Leptin levels in patients with psoriasis: A meta-analysis. Clin Exp Dermatol, 38:478–83

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.