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Ophthalmic Genetics Volume 37, 2016 - Issue 3
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Letters to the Journal

Genetic variants in complement pathway and ARMS2/HTRA1 genes and risk of age-related macular degeneration in a homogeneous population from central Greece

A. N. TsiloulisDepartment of Ophthalmology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larisa, GreeceCorrespondence[email protected]
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F. ZacharakiDepartment of Ophthalmology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larisa, GreeceView further author information
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M. G. KotoulaDepartment of Ophthalmology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larisa, GreeceView further author information
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D. Z. ChatzoulisDepartment of Ophthalmology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larisa, GreeceView further author information
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M. A. MorrisonDepartment of Ophthalmology and Visual Sciences, John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USAView further author information
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K. MayneDepartment of Ophthalmology and Visual Sciences, John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USAView further author information
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E. DardiotisDepartment of Neurology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larisa, GreeceView further author information
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I. L. StefanidisDepartment of Nephrology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larisa, GreeceView further author information
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P. AlmpanidouDepartment of Ophthalmology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larisa, GreeceView further author information
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M. M. DeAngelisDepartment of Ophthalmology and Visual Sciences, John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USAView further author information
&
E. E. TsironiDepartment of Ophthalmology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larisa, GreeceView further author information
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Pages 339-344 | Published online: 05 Feb 2016

References

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  • Francis PJ, Hamon SC, Ott J, et al. Polymorphisms in C2, CFB and C3 are associated with progression to advanced age related macular degeneration associated with visual loss. J Med Genet 2009;46:300–307.
  • Yang Z, Camp NJ, Sun H, et al. A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration. Science 2006;314:992–993.
  • Richardson AJ, Islam FA, Aung KZ, et al. An intergenic region between the tagSNP rs3793917 and rs11200638 in the HTRA1 gene indicates association with age-related macular degeneration. Invest Ophthalmol Vis Sci 2010;51:4932–4936.
  • Kaur I, Cantsilieris S, Katta S, et al. Association of the del443ins54 at the ARMS2 locus in Indian and Australian cohorts with age-related macular degeneration. Mol Vis 2013;19:822–828.
  • Fritsche LG, Chen W, Schu M, et al.; AMD Gene Consortium. Seven new loci associated with age-related macular degeneration. Nat Genet 2013;45:433–439.

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